Drug General Information (ID: D0145)
  Drug Name
Balsalazide
  Drug Type Small molecule
  Drug Synonymous
Balsalazida; Balsalazido; Balsalazidum; Colazal; Balsalazida [Spanish]; Balsalazide Disodium; Balsalazido [Spanish]; Balsalazidum [Latin]; Balsalazide (INN); Balsalazide [INN:BAN]; Colazal (TN); Colazide (TN); (3Z)-3-[[4-(2-carboxyethylcarbamoyl)phenyl]hydrazinylidene]-6-oxocyclohexa-1,4-diene-1-carboxylic acid; (E)-5-((4-(((2-Carboxyethyl)amino)carbonyl)phenyl)azo)-2-hydroxybenzoic acid; (E)-5-({p-[(2-carboxyethyl)carbamoyl]phenyl}azo)-2-salicylic acid; 3-(2-{4-[(2-carboxyethyl)carbamoyl]phenyl}hydrazinylidene)-6-oxocyclohexa-1,4-diene-1-carboxylic acid; 5-[(E)-{4-[(2-carboxyethyl)carbamoyl]phenyl}diazenyl]-2-hydroxybenzoic acid; 5-[4-(2-carboxy-ethylcarbamoyl)-phenylazo]-2-hydroxy-benzoic acid
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  Disease Class DD72: Indeterminate colitis
  Therapeutic Class Antiinflammatory Agents
  Structure Could Not Find 2D Structure
3D Structure 2D Structure
  Formula C17H15N3O6
  InChI 1S/C17H15N3O6/c21-14-6-5-12(9-13(14)17(25)26)20-19-11-3-1-10(2-4-11)16(24)18-8-7-15(22)23/h1-6,9,21H,7-8H2,(H,18,24)(H,22,23)(H,25,26)
  InChIKey IPOKCKJONYRRHP-UHFFFAOYSA-N
  Canonical SMILES C1=CC(=CC=C1C(=O)NCCC(=O)O)N=NC2=CC(=C(C=C2)O)C(=O)O
  External Link
Pubchem ID 54585
CAS Number 80573-04-2
CHEBI ID 267413
TTD ID D0A6KR
INTEDE ID DR2414

Drug-Drug Interaction Network
  Sunburst Graph
AM004  Affected intra/extra-hepatic metabolism
AM005  Affected excretion pathways
AM006  Pharmacodynamic additive effects
AM007  Pharmacodynamic antagonistic effects
BM018  Non-CYP450 enzyme inhibition
BM027  Decreased renal excretion due to nephrotoxicity
BM064  Increased risk of hypoglycemia
BM072  Increased risk of nephrotoxicity
BM107  Attenuated pharmacological effects (Unspecific)
  Relation Graph
 Full list of drugs interacting with Balsalazide
      Affected intra/extra-hepatic metabolism
   Non-CYP450 enzyme inhibition Drug Num:  3
Drug ID
 
Drug Name
Formula Pubchem ID Severity Level Interaction Detail REF
D0136
 
Azathioprine
 
C9H7N7O2S
 
2265 
Moderate    Inter Info   
[24], [25], [26], [27], [28], [29], [30], [31]
D1007
 
Mercaptopurine
 
C5H4N4S
 
667490 
Moderate    Inter Info   
[24], [25], [26], [27], [28], [29], [30], [31]
D1589
 
Tioguanine
 
C5H5N5S
 
2723601 
Moderate    Inter Info   
[146], [28], [29]
      Affected excretion pathways
   Decreased renal excretion due to nephrotoxicity Drug Num:  6
Drug ID
 
Drug Name
Formula Pubchem ID Severity Level Interaction Detail REF
D0668
 
Flucytosine
 
C4H4FN3O
 
3366 
Moderate    Inter Info   
[35]
D1389
 
Remdesivir
 
C27H35N6O8P
 
121304016 
Moderate    Inter Info   
[137], [6], [138], [139], [140]
D1543
 
Telbivudine
 
C10H14N2O5
 
159269 
Moderate    Inter Info   
[141]
D0576
 
Entecavir
 
C12H15N5O3
 
135398508 
Moderate    Inter Info   
[143]
D1193
 
Oxaliplatin
 
C8H14N2O4Pt
 
9887053 
Moderate    Inter Info   
[144]
D1241
 
Pemetrexed
 
C20H21N5O6
 
135410875 
Moderate    Inter Info   
[145]
      Pharmacodynamic additive effects
   Increased risk of hypoglycemia Drug Num:  8
Drug ID
 
Drug Name
Formula Pubchem ID Severity Level Interaction Detail REF
D0728
 
Glipizide
 
C21H27N5O4S
 
3478 
Moderate    Inter Info   
[36], [37], [38], [39], [40], [41], [42], [43], [44], [45], [46], [47], [48], [49], [50], [51], [52], [53], [54], [55], [56], [57], [58], [59], [60], [61], [62], [63], [64], [65], [66], [67], [68], [69], [70], [71], [72], [73], [74], [75], [76], [77], [78], [79], [80], [81], [82], [83], [84], [85], [86], [87], [88], [89], [90], [91], [92], [93], [94], [95], [96], [97], [98], [99], [100], [101], [102], [103], [104], [105], [106], [107], [108], [109], [110], [111], [112], [113], [114], [115], [116], [117], [118], [119], [120], [121], [122], [123], [124], [125], [126], [127], [128], [129], [130], [131], [132], [133], [134], [135], [136]
D0730
 
Glyburide
 
C23H28ClN3O5S
 
3488 
Moderate    Inter Info   
[36], [37], [38], [39], [40], [41], [42], [43], [44], [45], [46], [47], [48], [49], [50], [51], [52], [53], [54], [55], [56], [57], [58], [59], [60], [61], [62], [63], [64], [65], [66], [67], [68], [69], [70], [71], [72], [73], [74], [75], [76], [77], [78], [79], [80], [81], [82], [83], [84], [85], [86], [87], [88], [89], [90], [91], [92], [93], [94], [95], [96], [97], [98], [99], [100], [101], [102], [103], [104], [105], [106], [107], [108], [109], [110], [111], [112], [113], [114], [115], [116], [117], [118], [119], [120], [121], [122], [123], [124], [125], [126], [127], [128], [129], [130], [131], [132], [133], [134], [135], [136]
D1603
 
Tolbutamide
 
C12H18N2O3S
 
5505 
Moderate    Inter Info   
[36], [37], [38], [39], [40], [41], [42], [43], [44], [45], [46], [47], [48], [49], [50], [51], [52], [53], [54], [55], [56], [57], [58], [59], [60], [61], [62], [63], [64], [65], [66], [67], [68], [69], [70], [71], [72], [73], [74], [75], [76], [77], [78], [79], [80], [81], [82], [83], [84], [85], [86], [87], [88], [89], [90], [91], [92], [93], [94], [95], [96], [97], [98], [99], [100], [101], [102], [103], [104], [105], [106], [107], [108], [109], [110], [111], [112], [113], [114], [115], [116], [117], [118], [119], [120], [121], [122], [123], [124], [125], [126], [127], [128], [129], [130], [131], [132], [133], [134], [135], [136]
D0325
 
Chlorpropamide
 
C10H13ClN2O3S
 
2727 
Moderate    Inter Info   
[36], [37], [38], [39], [40], [41], [42], [43], [44], [45], [46], [47], [48], [49], [50], [51], [52], [53], [54], [55], [56], [57], [58], [59], [60], [61], [62], [63], [64], [65], [66], [67], [68], [69], [70], [71], [72], [73], [74], [75], [76], [77], [78], [79], [80], [81], [82], [83], [84], [85], [86], [87], [88], [89], [90], [91], [92], [93], [94], [95], [96], [97], [98], [99], [100], [101], [102], [103], [104], [105], [106], [107], [108], [109], [110], [111], [112], [113], [114], [115], [116], [117], [118], [119], [120], [121], [122], [123], [124], [125], [126], [127], [128], [129], [130], [131], [132], [133], [134], [135], [136]
D0727
 
Glimepiride
 
C24H34N4O5S
 
3476 
Moderate    Inter Info   
[36], [37], [38], [39], [40], [41], [42], [43], [44], [45], [46], [47], [48], [49], [50], [51], [52], [53], [54], [55], [56], [57], [58], [59], [60], [61], [62], [63], [64], [65], [66], [67], [68], [69], [70], [71], [72], [73], [74], [75], [76], [77], [78], [79], [80], [81], [82], [83], [84], [85], [86], [87], [88], [89], [90], [91], [92], [93], [94], [95], [96], [97], [98], [99], [100], [101], [102], [103], [104], [105], [106], [107], [108], [109], [110], [111], [112], [113], [114], [115], [116], [117], [118], [119], [120], [121], [122], [123], [124], [125], [126], [127], [128], [129], [130], [131], [132], [133], [134], [135], [136]
D1112
 
Nateglinide
 
C19H27NO3
 
5311309 
Moderate    Inter Info   
[36], [37], [38], [39], [40], [41], [42], [43], [44], [45], [46], [47], [48], [49], [50], [51], [52], [53], [54], [55], [56], [57], [58], [59], [60], [61], [62], [63], [64], [65], [66], [67], [68], [69], [70], [71], [72], [73], [74], [75], [76], [77], [78], [79], [80], [81], [82], [83], [84], [85], [86], [87], [88], [89], [90], [91], [92], [93], [94], [95], [96], [97], [98], [99], [100], [101], [102], [103], [104], [105], [106], [107], [108], [109], [110], [111], [112], [113], [114], [115], [116], [117], [118], [119], [120], [121], [122], [123], [124], [125], [126], [127], [128], [129], [130], [131], [132], [133], [134], [135], [136]
D1392
 
Repaglinide
 
C27H36N2O4
 
65981 
Moderate    Inter Info   
[36], [37], [38], [39], [40], [41], [42], [43], [44], [45], [46], [47], [48], [49], [50], [51], [52], [53], [54], [55], [56], [57], [58], [59], [60], [61], [62], [63], [64], [65], [66], [67], [68], [69], [70], [71], [72], [73], [74], [75], [76], [77], [78], [79], [80], [81], [82], [83], [84], [85], [86], [87], [88], [89], [90], [91], [92], [93], [94], [95], [96], [97], [98], [99], [100], [101], [102], [103], [104], [105], [106], [107], [108], [109], [110], [111], [112], [113], [114], [115], [116], [117], [118], [119], [120], [121], [122], [123], [124], [125], [126], [127], [128], [129], [130], [131], [132], [133], [134], [135], [136]
D1601
 
Tolazamide
 
C14H21N3O3S
 
5503 
Moderate    Inter Info   
[36], [37], [38], [39], [40], [41], [42], [43], [44], [45], [46], [47], [48], [49], [50], [51], [52], [53], [54], [55], [56], [57], [58], [59], [60], [61], [62], [63], [64], [65], [66], [67], [68], [69], [70], [71], [72], [73], [74], [75], [76], [77], [78], [79], [80], [81], [82], [83], [84], [85], [86], [87], [88], [89], [90], [91], [92], [93], [94], [95], [96], [97], [98], [99], [100], [101], [102], [103], [104], [105], [106], [107], [108], [109], [110], [111], [112], [113], [114], [115], [116], [117], [118], [119], [120], [121], [122], [123], [124], [125], [126], [127], [128], [129], [130], [131], [132], [133], [134], [135], [136]
   Increased risk of nephrotoxicity Drug Num:  73
Drug ID
 
Drug Name
Formula Pubchem ID Severity Level Interaction Detail REF
D0432
 
Deferasirox
 
C21H15N3O4
 
214348 
Major    Inter Info   
[1], [2]
D0761
 
Human botulinum neurotoxin A/B immune globulin
 
NA
 
NA
Major    Inter Info   
[3], [4], [5]
D0763
 
Human cytomegalovirus immune globulin
 
NA
 
NA
Major    Inter Info   
[3], [4], [5]
D0768
 
Human Rho(D) immune globulin
 
NA
 
NA
Major    Inter Info   
[3], [4], [5]
D0805
 
Inotersen
 
C230H318N69O121P19S19
 
121492004 
Major    Inter Info   
[6], [7]
D0831
 
Iodipamide
 
C20H14I6N2O6
 
3739 
Major    Inter Info   
[8], [9], [10], [11], [12], [13], [14]
D0832
 
Iodixanol
 
C35H44I6N6O15
 
3724 
Major    Inter Info   
[8], [9], [10], [11], [12], [13], [14]
D0833
 
Iohexol
 
C19H26I3N3O9
 
3730 
Major    Inter Info   
[8], [9], [10], [11], [12], [13], [14]
D0834
 
Iopamidol
 
C17H22I3N3O8
 
65492 
Major    Inter Info   
[8], [9], [10], [11], [12], [13], [14]
D0836
 
Iopromide
 
C18H24I3N3O8
 
3736 
Major    Inter Info   
[8], [9], [10], [11], [12], [13], [14]
D0837
 
Iothalamic acid
 
C11H9I3N2O4
 
3737 
Major    Inter Info   
[10], [11], [12]
D0838
 
Ioversol
 
C18H24I3N3O9
 
3741 
Major    Inter Info   
[8], [9], [10], [11], [12], [13], [14]
D0839
 
Ioxilan
 
C18H24I3N3O8
 
3743 
Major    Inter Info   
[8], [9], [10], [11], [12], [13], [14]
D0335
 
Cidofovir
 
C8H14N3O6P
 
60613 
Major    Inter Info   
[15]
D0472
 
Diatrizoate
 
C11H9I3N2O4
 
2140 
Major    Inter Info   
[8], [9], [10], [11], [12], [13], [14]
D0765
 
Human immunoglobulin G (intravenous)
 
NA
 
NA
Major    Inter Info   
[3], [4], [5]
D1476
 
Sirolimus
 
C51H79NO13
 
5284616 
Major    Inter Info   
[16], [17], [18]
D1526
 
Tacrolimus
 
C44H69NO12
 
445643 
Major    Inter Info   
[16], [17], [18]
D0022
 
Acyclovir
 
C8H11N5O3
 
135398513 
Moderate    Inter Info   
[19], [20], [21], [22]
D0056
 
Amikacin
 
C22H43N5O13
 
37768 
Moderate    Inter Info   
[19], [20], [21], [22]
D0075
 
Amphotericin B
 
C47H73NO17
 
5280965 
Moderate    Inter Info   
[19], [20], [21], [22]
D0076
 
Amphotericin B (cholesteryl sulfate)
 
C47H73NO17
 
5280965 
Moderate    Inter Info   
[20], [21], [22]
D0077
 
Amphotericin B (lipid complex)
 
C47H73NO17
 
5280965 
Moderate    Inter Info   
[20], [21], [22]
D0078
 
Amphotericin B (liposomal)
 
C47H73NO17
 
5280965 
Moderate    Inter Info   
[20], [21], [22]
D0142
 
Bacitracin
 
C66H103N17O16S
 
10909430 
Moderate    Inter Info   
[19], [20], [21], [22]
D0383
 
Colistimethate
 
C58H105N16O28S5-5
 
70789202 
Moderate    Inter Info   
[19], [20], [21], [22]
D0623
 
Etidronic acid
 
C2H8O7P2
 
3305 
Moderate    Inter Info   
[32], [33], [34]
D0709
 
Gallium nitrate
 
GaN3O9
 
61635 
Moderate    Inter Info   
[19], [20], [21], [22]
D0724
 
Givosiran
 
C78H139N11O30
 
119058042 
Moderate    Inter Info   
[19], [20], [21], [22]
D0829
 
Iobenguane (I-131)
 
C8H10IN3
 
60860 
Moderate    Inter Info   
[20], [21], [22]
D0876
 
Kanamycin
 
C18H36N4O11
 
6032 
Moderate    Inter Info   
[19], [20], [21], [22]
D0940
 
Lithium carbonate
 
CLi2O3
 
11125 
Moderate    Inter Info   
[20], [21], [22]
D0964
 
Lutetium Lu 177 dotatate
 
C65H87LuN14O19S2
 
76966897 
Moderate    Inter Info   
[19], [20], [21], [22]
D1030
 
Methoxyflurane
 
C3H4Cl2F2O
 
4116 
Moderate    Inter Info   
[19], [20], [21], [22]
D1091
 
Moxetumomab Pasudotox
 
NA
 
NA
Moderate    Inter Info   
[19], [20], [21], [22]
D1304
 
Plazomicin
 
C25H48N6O10
 
42613186 
Moderate    Inter Info   
[19], [20], [21], [22]
D1442
 
Salsalate
 
C14H10O5
 
5161 
Moderate    Inter Info   
[19], [20], [21], [22]
D1507
 
Streptomycin
 
C21H39N7O12
 
19649 
Moderate    Inter Info   
[19], [20], [21], [22]
D1542
 
Telavancin
 
C80H106Cl2N11O27P
 
3081362 
Moderate    Inter Info   
[19], [20], [21], [22]
D1549
 
Temsirolimus
 
C56H87NO16
 
6918289 
Moderate    Inter Info   
[19], [20], [21], [22]
D0210
 
Bromfenac
 
C15H12BrNO3
 
60726 
Moderate    Inter Info   
[19], [20], [21], [22]
D0252
 
Capreomycin
 
C50H88N28O15
 
3000502 
Moderate    Inter Info   
[19], [20], [21], [22]
D0298
 
Celecoxib
 
C17H14F3N3O2S
 
2662 
Moderate    Inter Info   
[19], [20], [21], [22]
D0344
 
Cisplatin
 
Cl2H6N2Pt
 
5702198 
Moderate    Inter Info   
[19], [20], [21], [22]
D0357
 
Clofarabine
 
C10H11ClFN5O3
 
119182 
Moderate    Inter Info   
[142]
D0476
 
Diclofenac
 
C14H11Cl2NO2
 
3033 
Moderate    Inter Info   
[19], [20], [21], [22]
D0489
 
Diflunisal
 
C13H8F2O3
 
3059 
Moderate    Inter Info   
[19], [20], [21], [22]
D0624
 
Etodolac
 
C17H21NO3
 
3308 
Moderate    Inter Info   
[19], [20], [21], [22]
D0645
 
Fenoprofen
 
C15H14O3
 
3342 
Moderate    Inter Info   
[19], [20], [21], [22]
D0680
 
Flurbiprofen
 
C15H13FO2
 
3394 
Moderate    Inter Info   
[19], [20], [21], [22]
D0694
 
Foscarnet
 
CH3O5P
 
3415 
Moderate    Inter Info   
[19], [20], [21], [22]
D0800
 
Indomethacin
 
C19H16ClNO4
 
3715 
Moderate    Inter Info   
[19], [20], [21], [22]
D0881
 
Ketoprofen
 
C16H14O3
 
3825 
Moderate    Inter Info   
[19], [20], [21], [22]
D0882
 
Ketorolac
 
C15H13NO3
 
3826 
Moderate    Inter Info   
[19], [20], [21], [22]
D0988
 
Meclofenamic acid
 
C14H11Cl2NO2
 
4037 
Moderate    Inter Info   
[20], [21], [22]
D0995
 
Meloxicam
 
C14H13N3O4S2
 
54677470 
Moderate    Inter Info   
[19], [20], [21], [22]
D1025
 
Methotrexate
 
C20H22N8O5
 
126941 
Moderate    Inter Info   
[19], [20], [21], [22]
D1097
 
Nabumetone
 
C15H16O2
 
4409 
Moderate    Inter Info   
[19], [20], [21], [22]
D1109
 
Naproxen
 
C14H14O3
 
156391 
Moderate    Inter Info   
[19], [20], [21], [22]
D1120
 
Neomycin
 
C23H46N6O13
 
8378 
Moderate    Inter Info   
[19], [20], [21], [22]
D1126
 
Netilmicin
 
C21H41N5O7
 
441306 
Moderate    Inter Info   
[19], [20], [21], [22]
D1196
 
Oxaprozin
 
C18H15NO3
 
4614 
Moderate    Inter Info   
[19], [20], [21], [22]
D1217
 
Pamidronic acid
 
C3H11NO7P2
 
4674 
Moderate    Inter Info   
[32], [33], [34]
D1246
 
Pentamidine
 
C19H24N4O2
 
4735 
Moderate    Inter Info   
[19], [20], [21], [22]
D1274
 
Phenylbutazone
 
C19H20N2O2
 
4781 
Moderate    Inter Info   
[19], [20], [21], [22]
D1300
 
Piroxicam
 
C15H13N3O4S
 
54676228 
Moderate    Inter Info   
[19], [20], [21], [22]
D1310
 
Polymyxin B
 
C56H98N16O13
 
49800004 
Moderate    Inter Info   
[19], [20], [21], [22]
D1520
 
Sulindac
 
C20H17FO3S
 
1548887 
Moderate    Inter Info   
[19], [20], [21], [22]
D1606
 
Tolmetin
 
C15H15NO3
 
5509 
Moderate    Inter Info   
[19], [20], [21], [22]
D1672
 
Valaciclovir
 
C13H20N6O4
 
135398742 
Moderate    Inter Info   
[20], [21], [22]
D1674
 
Valdecoxib
 
C16H14N2O3S
 
119607 
Moderate    Inter Info   
[19], [20], [21], [22]
D1680
 
Vancomycin
 
C66H75Cl2N9O24
 
14969 
Moderate    Inter Info   
[19], [20], [21], [22]
D1727
 
Zoledronic acid
 
C5H10N2O7P2
 
68740 
Moderate    Inter Info   
[147], [148], [149], [33], [150], [151], [152], [153], [154], [155], [34], [156]
      Pharmacodynamic antagonistic effects
   Attenuated pharmacological effects (Unspecific) Drug Num:  46
Drug ID
 
Drug Name
Formula Pubchem ID Severity Level Interaction Detail REF
D0079
 
Ampicillin
 
C16H19N3O4S
 
6249 
Moderate    Inter Info   
[23]
D0139
 
Azithromycin
 
C38H72N2O12
 
447043 
Moderate    Inter Info   
[23]
D0073
 
Amoxicillin
 
C16H19N3O5S
 
33613 
Moderate    Inter Info   
[23]
D0141
 
Bacampicillin
 
C21H27N3O7S
 
441397 
Moderate    Inter Info   
[23]
D0272
 
Cefadroxil
 
C16H17N3O5S
 
47965 
Moderate    Inter Info   
[23]
D0288
 
Cefpodoxime
 
C15H17N5O6S2
 
6335986 
Moderate    Inter Info   
[23]
D0289
 
Cefprozil
 
C18H19N3O5S
 
5281006 
Moderate    Inter Info   
[23]
D0290
 
Cefradine
 
C16H19N3O4S
 
38103 
Moderate    Inter Info   
[23]
D0293
 
Ceftibuten
 
C15H14N4O6S2
 
5282242 
Moderate    Inter Info   
[23]
D0297
 
Cefuroxime
 
C16H16N4O8S
 
5479529 
Moderate    Inter Info   
[23]
D0349
 
Clarithromycin
 
C38H69NO13
 
84029 
Moderate    Inter Info   
[23]
D0354
 
Clindamycin
 
C18H33ClN2O5S
 
446598 
Moderate    Inter Info   
[23]
D0369
 
Cloxacillin
 
C19H18ClN3O5S
 
6098 
Moderate    Inter Info   
[23]
D0438
 
Delafloxacin
 
C18H12ClF3N4O4
 
487101 
Moderate    Inter Info   
[23]
D0712
 
Gatifloxacin
 
C19H22FN3O4
 
5379 
Moderate    Inter Info   
[23]
D0919
 
Levofloxacin
 
C18H20FN3O4
 
149096 
Moderate    Inter Info   
[23]
D0931
 
Lincomycin
 
C18H34N2O6S
 
3000540 
Moderate    Inter Info   
[23]
D1070
 
Minocycline
 
C23H27N3O7
 
54675783 
Moderate    Inter Info   
[23]
D1155
 
Norfloxacin
 
C16H18FN3O3
 
4539 
Moderate    Inter Info   
[23]
D1165
 
Ofloxacin
 
C18H20FN3O4
 
4583 
Moderate    Inter Info   
[23]
D1499
 
Sparfloxacin
 
C19H22F2N4O3
 
60464 
Moderate    Inter Info   
[23]
D1516
 
Sulfamethoxazole
 
C10H11N3O3S
 
5329 
Moderate    Inter Info   
[23]
D0257
 
Carbenicillin
 
C17H18N2O6S
 
20824 
Moderate    Inter Info   
[23]
D0271
 
Cefaclor
 
C15H14ClN3O4S
 
51039 
Moderate    Inter Info   
[23]
D0277
 
Cefdinir
 
C14H13N5O5S2
 
6915944 
Moderate    Inter Info   
[23]
D0301
 
Cephalexin
 
C16H17N3O4S
 
27447 
Moderate    Inter Info   
[23]
D0313
 
Chloramphenicol
 
C11H12Cl2N2O5
 
5959 
Moderate    Inter Info   
[23]
D0340
 
Cinoxacin
 
C12H10N2O5
 
2762 
Moderate    Inter Info   
[23]
D0341
 
Ciprofloxacin
 
C17H18FN3O3
 
2764 
Moderate    Inter Info   
[23]
D0350
 
Clavulanic acid
 
C8H9NO5
 
5280980 
Moderate    Inter Info   
[23]
D0480
 
Dicloxacillin
 
C19H17Cl2N3O5S
 
18381 
Moderate    Inter Info   
[23]
D0530
 
Doxycycline
 
C22H24N2O8
 
54671203 
Moderate    Inter Info   
[23]
D0573
 
Enoxacin
 
C15H17FN4O3
 
3229 
Moderate    Inter Info   
[23]
D0597
 
Erythromycin
 
C37H67NO13
 
12560 
Moderate    Inter Info   
[23]
D0740
 
Grepafloxacin
 
C19H22FN3O3
 
72474 
Moderate    Inter Info   
[23]
D0943
 
Lomefloxacin
 
C17H19F2N3O3
 
3948 
Moderate    Inter Info   
[23]
D1092
 
Moxifloxacin
 
C21H24FN3O4
 
152946 
Moderate    Inter Info   
[23]
D1102
 
Nalidixic acid
 
C12H12N2O3
 
4421 
Moderate    Inter Info   
[23]
D1145
 
Nitrofurantoin
 
C8H6N4O5
 
6604200 
Moderate    Inter Info   
[23]
D1268
 
Phenoxymethylpenicillin
 
C16H18N2O5S
 
6869 
Moderate    Inter Info   
[23]
D1513
 
Sulfadiazine
 
C10H10N4O2S
 
5215 
Moderate    Inter Info   
[23]
D1515
 
Sulfamethizole
 
C9H10N4O2S2
 
5328 
Moderate    Inter Info   
[23]
D1519
 
Sulfisoxazole
 
C11H13N3O3S
 
5344 
Moderate    Inter Info   
[23]
D1564
 
Tetracycline
 
C22H24N2O8
 
54675776 
Moderate    Inter Info   
[23]
D1645
 
Trimethoprim
 
C14H18N4O3
 
5578 
Moderate    Inter Info   
[23]
D1657
 
Trovafloxacin
 
C20H15F3N4O3
 
62959 
Moderate    Inter Info   
[23]
References
1 Product Information. Exjade (deferasirox). Novartis Pharmaceuticals, East Hanover, NJ.
2 Rafat C, Fakhouri F, Ribeil JA, Delarue R, Le Quintrec M "Fanconi Syndrome Due to Deferasirox." Am J Kidney Dis (2009):. [PMID: 19493602]
3 Guo X, Nzerue C "How to prevent, recognize, and treat drug-induced nephrotoxicity.".
4 Centers for Disease Control and Prevention (CDC). Renal insufficiency and failure associated with immune globulin intravenous therapy--United States, 1985-1998.?MMWR Morb Mortal Wkly Rep. 1999;48(24):518-521. [PMID: 10401909]
5 Product Information. BabyBIG (botulism immune globulin). FFF Enterprises, Temecula, CA.
6 Cerner Multum, Inc. "UK Summary of Product Characteristics.".
7 Product Information. Tegsedi (inotersen). Akcea Therapeutics, Cambridge, MA.
8 Wong GT, Lee EY, Irwin MG. Contrast induced nephropathy in vascular surgery.?Br J Anaesth. 2016;117 Suppl 2:ii63-ii73. [PMID: 27566809]
9 Bennett WM, Porter GA "Nephrotoxicity of common drugs used by urologists." Urol Clin North Am 17 (1990): 145-56. [PMID: 2407013]
10 Bentley ML, Corwin HL, Dasta J "Drug-induced acute kidney injury in the critically ill adult: recognition and prevention strategies." Crit Care Med 38(6 Suppl) (2010): S169-74. [PMID: 20502171]
11 Dubrovskaya Y, Prasad N, Lee Y, Esaian D, Figueroa DA, Tam VH "Risk factors for nephrotoxicity onset associated with polymyxin B therapy." J Antimicrob Chemother 70 (2015): 1903-7. [PMID: 25652747]
12 Kellum JA, Leblanc M, Venkataraman R "Acute renal failure." BMJ Clin Evid 9 (2008): 2001. [PMID: 19445797]
13 Marcos LA, Camins BC, Ritchie DJ, Casabar E, Warren DK "Acute renal insufficiency during telavancin therapy in clinical practice." J Antimicrob Chemother 67 (2012): 723-6. [PMID: 22174040]
14 van den Berk G, Tonino S, de Fijter C, Smit W, Schultz MJ "Bench-to-bedside review: Preventative measures for contrast-induced nephropathy in critically ill patients." Crit Care 9 (2005): 361-70. [PMID: 16137385]
15 Product Information. Vistide (cidofovir). Gilead Sciences, Foster City, CA.
16 Product Information. Prograf (tacrolimus). Fujisawa, Deerfield, IL.
17 Product Information. Rapamune (sirolimus) Wyeth-Ayerst Laboratories, Philadelphia, PA.
18 Sheiner PA, Mor E, Chodoff L, Glabman S, Emre S, Schwartz ME, Miller CM "Acute renal, failure associated with the use of ibuprofen in two liver transplant recipients on FK506." Transplantation 57 (1994): 1132-3. [PMID: 7513099]
19 Novis BH, Korzets Z, Chen P, Bernheim J "Nephrotic syndrome after treatment with 5-aminosalicylic acid." Br Med J (Clin Res Ed) 296 (1988): 1442. [PMID: 3132281]
20 Product Information. Canasa (mesalamine (5-aminosalicylic acid)). Axcan Scandipharm Inc, Birmingham, AL.
21 Product Information. Lialda (mesalamine (5-aminosalicylic acid)). Shire US Inc, Florence, KY.
22 Schreiber S. Hamling J, Zehnter E, et al "Renal tubular dysfunction in patients with inflammatory bowel disease treated with aminosalicylate." Gut 40 (1997): 761-6. [PMID: 9245930]
23 Product Information. Colazal (balsalazide) Salix Pharmaceuticals, Palo Alto, CA.
24 Lewis LD, Benin A, Szumlanski CL, et al. "Olsalazine and 6-mercaptopurine-related bone marrow suppression: a possible drug-drug interaction." Clin Pharmacol Ther 62 (1997): 464-75. [PMID: 9357398]
25 Lewis LD, Benin A, Szumlanski CL, Otterness DM, Lennard L, Weinshilboum RM, Nierenberg DW "Olsalazine and 6-mercaptopurine-related bone marrow suppression: A possible drug-drug interaction (Vol 62, pg 464, 1997)." Clin Pharmacol Ther 67 (2000): 431. [PMID: 9357398]
26 Lowry PW, Franklin CL, Weaver AL, et al. "Leucopenia resulting from a drug interaction between azathioprine or 6-mercaptopurine and mesalamine, sulphasalazine, or balsalazide." Gut 49 (2001): 656-64. [PMID: 11600468]
27 Lowry PW, Szumlanski CL, Weinshilboum RM, Sandborn WJ "Balsalazide and azathiprine or 6-mercaptopurine: evidence for a potentially serious drug interaction [letter comment." Gastroenterology 116 (1999): 1505-6. [PMID: 10391741]
28 Product Information. Imuran (azathioprine). Glaxo Wellcome, Research Triangle Park, NC.
29 Product Information. Purinethol (mercaptopurine). Glaxo Wellcome, Research Triangle Pk, NC.
30 Product Information. Tabloid (thioguanine). Prasco Laboratories, Cincinnati, OH.
31 Szumlanski CL, Weinshilboum RM "Sulphasalazine inhibition of thiopurine methyltransferase: possible mechanism for interaction with 6-mercaptopurine and azathioprine." Br J Clin Pharmacol 39 (1995): 456-9. [PMID: 7640156]
32 Chang JT, Green L, Beitz J "Renal failure with the use of zoledronic acid." N Engl J Med 349 (2003): 1676-9 discussion 1676-9. [PMID: 14573746]
33 Kanis JA, Preston CJ, Yates AJ, Percival RC, Mundy KI, Russell RG "Effects of intravenous diphosphonates on renal function." Lancet 1 (1983): 1328. [PMID: 6134112]
34 Product Information. Zometa (zoledronic acid). Novartis Pharmaceuticals, East Hanover, NJ.
35 Product Information. Ancobon (flucytosine). Roche Laboratories, Nutley, NJ.
36 Abad S, Moachon L, Blanche P, Bavoux F, Sicard D, Salmon-Ceron D "Possible interaction between glicazide, fluconazole and sulfamethoxazole resulting in severe hypoglycaemia." Br J Clin Pharmacol 52 (2001): 456-7. [PMID: 11678792]
37 Ahmad S "Drug interaction induces hypoglycemia." J Fam Pract 40 (1995): 540-1. [PMID: 7775905]
38 Ahmad S "Gemfibrozil: interaction with glyburide." South Med J 84 (1991): 102. [PMID: 1898783]
39 Aleyassine H, Gardiner RJ "Dual action of antidepressant drugs (MAO inhibitors) on insulin release." Endocrinology 96 (1975): 702-10. [PMID: 1090438]
40 Aleyassine H, Lee SH "Inhibition of insulin release by substrates and inhibitors of monoamine oxidase." Am J Physiol 222 (1972): 565-9. [PMID: 5022664]
41 Almirall J, Montoliu J, Torras A, Revert L "Propoxyphene-induced hypoglycemia in a patient with chronic renal failure." Nephron 53 (1989): 273-5. [PMID: 2797348]
42 Arauz-Pacheco C, Ramirez LC, Rios JM, Raskin P "Hypoglycemia induced by angiotensin-converting enzyme inhibitors in patients with non-insulin-dependent diabetes receiving sulfonylurea therapy." Am J Med 89 (1990): 811-3. [PMID: 2123605]
43 Asplund K, Wiholm BE, Lithner F "Glibenclamide-associated hypoglycaemia: a report on 57 cases." Diabetologia 24 (1983): 412-7. [PMID: 6411511]
44 Baciewicz AM, Swafford WB Jr "Hypoglycemia induced by the interaction of chlorpropamide and co-trimoxazole." Drug Intell Clin Pharm 18 (1984): 309-10. [PMID: 6609055]
45 Barbato M "Another problem with Kinidin." Med J Aust 141 (1984): 685. [PMID: 6436654]
46 Baron SH "Salicylates as hypoglycemic agents." Diabetes Care 5 (1982): 64-71. [PMID: 6754304]
47 Cacoub P, Deray G, Baumelou A, Grimaldi A, Soubrie C, Jacobs C "Disopyramide-induced hypoglycemia: case report and review of the literature." Fundam Clin Pharmacol 3 (1989): 527-35. [PMID: 2691378]
48 Cattaneo AG, Caviezel F, Pozza G "Pharmacological interaction between tolbutamide and acetylsalicylic acid: study on insulin secretion in man." Int J Clin Pharmacol Ther Toxicol 28 (1990): 229-34. [PMID: 2198232]
49 Christensen LK, Hansen JM, Kristensen M "Sulphaphenazole-induced hypoglycemic attacks in tolbutamide-treated diabetics." Lancet 2 (1963): 1298-301. [PMID: 14071924]
50 Cooper AJ, Ashcroft G "Potentiation of insulin hypoglycaemia by M.A.O.I. antidepressant drugs." Lancet 1 (1966): 407-9. [PMID: 4159787]
51 Croxson MS, Shaw DW, Henley PG, Gabriel HDLL "Disopyramide-induced hypoglycaemia and increased serum insulin." N Z Med J July (1987): 407-8. [PMID: 3330586]
52 Darcy PF, Griffin JP "Interactions with drugs used in the treatment of depressive illness." Adverse Drug React Toxicol Rev 14 (1995): 211-31. [PMID: 8845455]
53 Daubresse JC, Daigneux D, Bruwier M, Luyckx A, Lefebvre PJ "Clofibrate and diabetes control in patients treated with oral hypoglycaemic agents." Br J Clin Pharmacol 7 (1979): 599-603. [PMID: 380614]
54 Daubresse JC, Luyckx AS, Lefebvre PJ "Potentiation of hypoglycemic effect of sulfonylureas by clofibrate." N Engl J Med 294 (1976): 613. [PMID: 1246250]
55 David DS, Steere AC Jr, Pi-Sunyer XF, Sakai S, Clark SB "Aspirin-induced hypoglycaemia in a patient on haemodialysis." Lancet 2 (1971): 1092-3. [PMID: 4106934]
56 Davis TM, Karbwang J, Looareesuwan S, et al "Comparative effects of quinine and quinidine on glucose metabolism in healthy volunteers." Br J Clin Pharmacol 30 (1990): 397-403. [PMID: 2223418]
57 de Salcedo I, Gorringe AL, Silva JL, Santos JA "Gemfibrozil in a group of diabetics." Proc R Soc Med 69 (1976): 64-70. [PMID: 1019155]
58 Deeg MA, Lipkin EW "Hypoglycemia associated with the use of fluoxetine." West J Med 164 (1996): 262-3. [PMID: 8775944]
59 Diwan PV, Sastry MS, Satyanarayana NV "Potentiation of hypoglycemic response of glibenclamide by piroxicam in rats and humans." Indian J Exp Biol 30 (1992): 317-9. [PMID: 1459600]
60 Feher MD, Amiel S "ACE inhibitors and hypoglycaemia." Lancet 346 (1995): 125-6. [PMID: 7603199]
61 Feldman JM, Chapman B "Monoamine oxidase inhibitors: nature of their interaction with rabbit pancreatic islets to alter insulin secretion." Diabetologia 11 (1975): 487-94. [PMID: 1107123]
62 Ferrari C, Fressati S, Romussi M, et al. "Effects of short-term clofibrate administration on glucose tolerance and insulin secretion in patients with chemical diabetes or hypertriglyceridemia." Metabolism 26 (1977): 129-39. [PMID: 834147]
63 Ferriere M, Lachkar H, Richard JL, Bringer J, Orsetti A, Mirouze J "Captopril and insulin sensitivity." Ann Intern Med 102 (1985): 134-5. [PMID: 3881067]
64 Field JB, Ohta M, Boyle C, Remer A "Potentiation of acetohexamide hypoglycemia by phenylbutazone." N Engl J Med 277 (1967): 889-94. [PMID: 6061822]
65 Fogari R, Zoppi A, Corradi L, Pierangelo L, Mugellini A, Lusardi P "Comparative effects of lisinopril and losartan on insulin sensitivity in the treatment of non diabetic hypertension." Br J Clin Pharmacol 46 (1998): 467-71. [PMID: 9833600]
66 Giugliano D, Ceriello A, Saccomanno F, et al "Effects of salicylate, tolbutamide, and prostaglandin E2 on insulin responses to glucose in noninsulin-dependent diabetes mellitus." J Clin Endocrinol Metab 61 (1985): 160-6. [PMID: 3923028]
67 Goldberg IJ, Brown LK, Rayfield EJ "Disopyramide (norpace)-induced hypoglycemia." Am J Med 69 (1980): 463-6. [PMID: 6998294]
68 Harris EL "Adverse reactions to oral antidiabetic agents." Br Med J 3 (1971): 29-30. [PMID: 5091891]
69 Harrison LC, King-Roach A, Martin FI, Melick RA "The effect of fenfluramine on insulin binding and on basal and insulin-stimulated oxidation of 1-C-glucose by human adipose tissue." Postgrad Med J 51 Suppl 1 (1975): 110-4. [PMID: 1219664]
70 Hartmann D, Korn A, Komjati M, Heinz G, Haefelfinger P, Defoin R, Waldhausl WK "Lack of effect of tenoxicam on dynamic responses to concurrent oral doses of glucose and glibenclamide." Br J Clin Pharmacol 30 (1990): 245-52. [PMID: 2119677]
71 Hayashi S, Horie M, Tsuura Y, Ishida H, Okada Y, Seino Y, Sasayama S "Disopyramide blocks pancreatic ATP-sensitive K+ channels and enhances insulin release." Am J Physiol 265 (1993): c337-42. [PMID: 8368263]
72 Hekimsoy Z, Biberoglu S, Comlekci A, Tarhan O, Mermut C, Biberoglu K "Trimethoprim/sulfamethoxazole-induced hypoglycemia in a malnourished patient with severe infection." Eur J Endocrinol 136 (1997): 3046. [PMID: 9100556]
73 Hellman B "Potentiating effects of drugs on the binding of glibenclamide to pancreatic beta cells." Metabolism 23 (1974): 839-46. [PMID: 4212254]
74 Herings RMC, Deboer A, Stricker BHC, Leufkens HGM, Porsius A "Hypoglycaemia associated with use of inhibitors of angiotensin converting enzyme." Lancet 345 (1995): 1195-8. [PMID: 7739305]
75 Hundal RS, Petersen KF, Mayerson AB, et al "Mechanism by which high-dose aspirin improves glucose metabolism in type 2 diabetes." J Clin Invest 109 (2002): 1321-6. [PMID: 12021247]
76 Iida H, Morita T, Suzuki E, Iwasawa K, Toyooka T, Nakajima T "Hypoglycemia induced by interaction between clarithromycin and disopyramide." Jpn Heart J 40 (1999): 91-6. [PMID: 10370402]
77 Johnson J, Dobmeier M "Symptomatic hypoglycemia secondary to a glipizide-trimethoprim/sulfamethoxazole drug interaction." DICP 24 (1990): 250-1. [PMID: 2316232]
78 Johnson JA, Kappel JE, Sharif MN "Hypoglycemia secondary to trimethoprim/sulfamethoxazole administration in a renal transplant patient." Ann Pharmacother 27 (1993): 304-6. [PMID: 8453166]
79 Konttinen A, Kuisma I, Ralli R, Pohjola S, Ojala K "The effect of gemfibrozil on serum lipids in diabetic patients." Ann Clin Res 11 (1979): 240-5. [PMID: 398183]
80 Kradjan WA, Witt DM, Opheim KE, Wood FC "Lack of interaction between glipizide and co-trimoxazole." J Clin Pharmacol 34 (1994): 997-1002. [PMID: 7836551]
81 Kubacka RT, Antla EJ, Juhl RP, Welshman IR "Effects of aspirin and ibuprofen on the pharmacokinetics and pharmacodynamics of glyburide in healthy subjects." Ann Pharmacother 30 (1996): 20-6. [PMID: 8773160]
82 Lozada A, Dujovne CA "Drug interactions with fibric acids." Pharmacol Ther 63 (1994): 163-76. [PMID: 7809177]
83 Lumholtz B, Siersbaek-Nielsen K, Skovsted L, Kampmann J, Hansen JM "Sulfamethizole-induced inhibition of diphenylhydantoin, tolbutamide, and warfarin metabolism." Clin Pharmacol Ther 17 (1975): 731-4. [PMID: 1139863]
84 Morris AD, Newton RW, Boyle DI, et al. "ACE inhibitor use is associated with hospitalization for severe hypoglycemia in patients with diabetes." Diabetes Care 20 (1997): 1363-7. [PMID: 9283780]
85 Morrison PJ, Rogers HJ, Spector RG, Bradbrook ID, John VA "Effect of pirprofen on glibenclamide kinetics and response." Br J Clin Pharmacol 14 (1982): 123-6. [PMID: 6809024]
86 Murakami K, Nambu S, Koh H, Kobayashi M, Shigeta Y "Clofibrate enhances the affinity of insulin receptors in non-insulin dependent diabetes mellitus." Br J Clin Pharmacol 17 (1984): 89-91. [PMID: 6362704]
87 Nakabayashi H, Ito T, Igawa T, Hiraiwa Y, Imamura T, Seta T, Kawato M, Usukura N, Takeda R "Disopyramide induces insulin secretion and plasma glucose diminution: studies using the in situ canine pancreas." Metabolism 38 (1989): 179-83. [PMID: 2643753]
88 Nappi JM, Dhanani S, Lovejoy JR, VanderArk C "Severe hypoglycemia associated with disopyramide." West J Med 138 (1983): 95-7. [PMID: 6404062]
89 Niemi M, Backman JT, Neuvonen M, Laitila J, Neuvonen PJ, Kivisto KT "Effects of fluconazole and fluvoxamine on the pharmacokinetics and pharmacodynamics of glimepiride." Clin Pharmacol Ther 69 (2001): 194-200. [PMID: 11309547]
90 Nikkila EA, Ylikahri R, Huttunen JK "Gemfibrozil: effect on serum lipids, lipoproteins, postheparin plasma lipase activities and glucose tolerance in primary hypertriglyceridaemia." Proc R Soc Med 69 (1976): 58-63. [PMID: 190608]
91 Paolisso G, Balbi V, Gambardella A, Varricchio G, Tortoriello R, Saccomanno F, Amato L, Varricchio M "Lisinopril administration improves insulin action in aged patients with hypertension." J Hum Hypertens 9 (1995): 541-6. [PMID: 7562882]
92 Pestell RG, Crock PA, Ward GM, Alford FP, Best JD "Fenfluramine increases insulin action in patients with NIDDM." Diabetes Care 12 (1989): 252-8. [PMID: 2495916]
93 Petitpierre B, Perrin L, Rudhardt M, et al "Behaviour of chlorpropamide in renal insufficiency and under the effect of associated drug therapy." Int J Clin Pharmacol 6 (1972): 120-4. [PMID: 4638970]
94 Phillips AF, Matty PJ, Porte PJ, Raye JR "Inhibition of glucose-induced insulin secretion by indomethacin and sodium salicylate in the fetal lamb." Am J Obstet Gynecol 148 (1984): 481-7. [PMID: 6364813]
95 Phillips RE, Looareesuwan S, White NJ, et al "Hypoglycaemia and antimalarial drugs: quinidine and release of insulin." Br Med J 292 (1986): 1319-21. [PMID: 3085830]
96 Pollak PT, Mukherjee SD, Fraser AD "Sertraline-induced hypoglycemia." Ann Pharmacother 35 (2001): 1371-4. [PMID: 11724085]
97 Pond SM, Birkett DJ, Wade DN "Mechanisms of inhibition of tolbutamide metabolism: phenylbutazone, oxyphenbutazone, sulfaphenazole." Clin Pharmacol Ther 22 (1977): 573-9. [PMID: 913025]
98 Prince RL, Larkins RG, Alford FP "The effect of acetylsalicylic acid on plasma glucose and the response of glucose regulatory hormones to intravenous glucose and arginine in insulin treated diabetics and normal subjects." Metabolism 30 (1981): 293-8. [PMID: 7010074]
99 Product Information. Amaryl (glimepiride). Hoechst Marion-Roussel Inc, Kansas City, MO.
100 Product Information. Apidra (insulin glulisine). Aventis Pharmaceuticals, Bridgewater, NJ.
101 Product Information. Diabeta (glyburide). Hoechst Marion-Roussel Inc, Kansas City, MO.
102 Product Information. Diabinese (chlorpropamide). Pfizer US Pharmaceuticals, New York, NY.
103 Product Information. Dymelor (acetohexamide) Lilly, Eli and Company, Indianapolis, IN.
104 Product Information. Glucotrol (glipizide). Pfizer US Pharmaceuticals, New York, NY.
105 Product Information. Increlex (mecasermin). Tercica Inc, Brisbane, CA.
106 Product Information. Micronase (glyburide). Pharmacia and Upjohn, Kalamazoo, MI.
107 Product Information. Orinase (tolbutamide) Pharmacia and Upjohn, Kalamazoo, MI.
108 Product Information. Prandin (repaglinide). Novo Nordisk Pharmaceuticals Inc, Princeton, NJ.
109 Product Information. Starlix (nateglinide) Novartis Pharmaceuticals, East Hanover, NJ.
110 Product Information. Tolinase (tolazamide) Pharmacia and Upjohn, Kalamazoo, MI.
111 Quevedo SF, Krauss DS, Chazan JA, et al "Fasting hypoglycemia secondary to disopyramide therapy." JAMA 245 (1981): 2424. [PMID: 6785461]
112 Ravic M, Johnston A, Turner P "Clinical pharmacological studies of some possible interactions of lornoxicam with other drugs." Postgrad Med J 66 (1990): s30-4. [PMID: 2126624]
113 Richardson T, Foster J, Mawer GE "Enhancement by sodium salicylate of the blood glucose lowering effect of chlorpropamide-drug interaction or summation of similar effects." Br J Clin Pharmacol 22 (1986): 43-8. [PMID: 3527244]
114 Rubin M, Zakheim B, Pitchumoni C "Disopyramide-induced profound hypoglycemia." N Y State J Med July,Aug,S (1983): 1057-8. [PMID: 6579404]
115 Salmela PI, Sotaniemi EA, Viikari J, et al "Fenfluramine therapy in non-insulin-dependent diabetic patients effects on body weight, glucose homeostasis, serum lipoproteins, and antipyrine metabolism." Diabetes Care 4 (1981): 535-40. [PMID: 6751729]
116 Sawka AM, Burgart V, Zimmerman D "Loss of awareness of hypoglycemia temporally associated with selective serotonin reuptake inhibitors." Diabetes Care 24 (2001): 1845-6. [PMID: 11574457]
117 Semel JD, Wortham E, Karl DM "Fasting hypoglycemia associated with disopyramide." Am Heart J 106 (1983): 1160-1. [PMID: 6356848]
118 Shah SJ, Bhandarkar SD, Satoskar RS "Drug interaction between chlorpropamide and non-steroidal anti-flammatory drugs, ibuprofen and phenylbutazone." Int J Clin Pharmacol Ther Toxicol 22 (1984): 470-2. [PMID: 6500764]
119 Sievenpiper JL, Arnason JT, Leiter LA, Vuksan V "Variable effects of American ginseng: a batch of American ginseng (Panax quinquefolius L.) with a depressed ginsenoside profile does not affect postprandial glycemia." Eur J Clin Nutr 57 (2003): 243-8. [PMID: 12571655]
120 Sjoberg S, Wiholm BE, Gunnarsson R, Emilsson H, Thunberg E, Christenson I, Ostman J "Lack of pharmacokinetic interaction between glibenclamide and trimethoprim-sulphamethoxazole." Diabet Med 4 (1987): 245-7. [PMID: 2956028]
121 Slade IH, and Iosefa RN "Fatal hypoglycemic coma from the use of tolbutamide in elderly patients: report of two cases." J Am Geriatr Soc 15 (1967): 948-50. [PMID: 6046558]
122 Sone H, Takahashi A, Yamada N "Ibuprofen-related hypoglycemia in a patient receiving sulfonylurea." Ann Intern Med 134 (2001): 344. [PMID: 11182854]
123 Storlien LH, Thorburn AW, Smythe GA, Jenkins AB, Chisholm DJ, Kraegen EW "Effect of d-fenfluramine on basal glucose turnover and fat-feeding-induced insulin resistance in rats." Diabetes 38 (1989): 499-503. [PMID: 2647557]
124 Strathman I, Schubert EN, Cohen A, Nitzberg DM "Hypoglycemia in patients receiving disopyramide phosphate." Drug Intell Clin Pharm 17 (1983): 635-8. [PMID: 6413187]
125 Tannenbaum H, Anderson LG, Soeldner JS "Phenylbutazone-tolbutamide drug interaction." N Engl J Med 290 (1974): 344. [PMID: 4809290]
126 Tran PO, Gleason CE, Robertson RP "Inhibition of interleukin-1beta-induced COX-2 and EP3 gene expression by sodium salicylate enhances pancreatic islet beta-cell function." Diabetes 51 (2002): 1772-8. [PMID: 12031964]
127 Tremaine LM, Wilner KD, Preskorn SH "A study of the potential effect of sertraline on the pharmacokinetics and protein binding of tolbutamide." Clin Pharmacokinet 32(Suppl 1) (1997): 31-36. [PMID: 9068933]
128 Turtle JR, Burgess JA "Hypoglycemic action of fenfluramine in diabetes mellitus." Diabetes 22 (1973): 858-67. [PMID: 4749404]
129 Verdy M, Charbonneau L, Verdy I, Belanger R, Bolte E, Chiasson JL "Fenfluramine in the treatment of non-insulin-dependent diabetics: hypoglycemic versus anorectic effect." Int J Obes 7 (1983): 289-97. [PMID: 6629637]
130 Vuksan V, Sievenpiper JL, Koo VY, et al "American ginseng (Panax quinquefolius L) reduces postprandial glycemia in nondiabetic subjects and subjects with type 2 diabetes mellitus." Arch Intern Med 160 (2000): 1009-13. [PMID: 10761967]
131 Vuksan V, Stavro MP, Sievenpiper JL, et al "Similar postprandial glycemic reductions with escalation of dose and administration time of American ginseng in type 2 diabetes." Diabetes Care 23 (2000): 1221-6. [PMID: 10977009]
132 Whitcroft IA, Thomas JM, Rawsthorne A, et al "Effects of alpha and beta adrenoceptor blocking drugs and ACE inhibitors on long term glucose and lipid control in hypertensive non-insulin dependent diabetics." Horm Metab Res Suppl 22 (1990): 42-6. [PMID: 1975246]
133 Wiederholt IC, Genco M, Foley JM "Recurrent episodes of hypoglycemia induced by propoxyphene." Neurology 17 (1967): 703-6. [PMID: 6067489]
134 Wing LM, Miners JO "Cotrimoxazole as an inhibitor of oxidative drug metabolism: effects of trimethoprim and sulphamethoxazole separately and combined on tolbutamide disposition." Br J Clin Pharmacol 20 (1985): 482-5. [PMID: 3878154]
135 World Health Organization "WHO Public Assessment Reports (WHOPARs).".
136 Wu B, Sato T, Kiyosue T, Arita M "Blockade of 2,4-dinitrophenol induced ATP sensitive potassium current in guinea pig ventricular myocytes by class I antiarrhythmic drugs." Cardiovasc Res 26 (1992): 1095-101. [PMID: 1291087]
137 Cerner Multum, Inc. "Australian Product Information.".
138 European Medicines Agency "Summary on compassionate use. Remdesivir Gilead.".
139 Gilead Sciences, Inc "About Remdesivir.".
140 US Food and Drug Administration "Fact sheet for health care providers emergency use authorization (EUA) of remdesivir (GS-5734TM)".
141 Product Information. Tyzeka (telbivudine). IDEC Pharmaceuticals Corporation, San Diego, CA.
142 Product Information. Clolar (clofarabine). sanofi-aventis, Bridgewater, NJ.
143 Product Information. Baraclude (entecavir). Bristol-Myers Squibb, Princeton, NJ.
144 Product Information. Eloxatin (oxaliplatin). Sanofi Winthrop Pharmaceuticals, New York, NY.
145 Product Information. Alimta (pemetrexed). Lilly, Eli and Company, Indianapolis, IN.
146 Lowry PW, Szumlanski CL, Weinshilboum RM, Sandborn WJ "Balsalazide and azathiprine or 6-mercaptopurine: evidence for a potentially serious drug interaction [letter comment." Gastroenterology 116 (1999): 1505-6. [PMID: 10391741]
147 Banerjee D, Asif A, Striker L, Preston RA, Bourgoignie JJ, Roth D "Short-term, high-dose pamidronate-induced acute tubular necrosis: The postulated mechanisms of bisphosphonate nephrotoxicity." Am J Kidney Dis 41 (2003): E18. [PMID: 12778436]
148 Chang JT, Green L, Beitz J "Renal failure with the use of zoledronic acid." N Engl J Med 349 (2003): 1676-9 discussion 1676-9. [PMID: 14573746]
149 Janssen Van Doorn K, Neyns B, Van Der Niepen P, Verbeelen D "Pamidronate-related nephrotoxicity (tubulointerstitial nephritis) in a patient with osteolytic bone metastases." Nephron 89 (2001): 467-8. [PMID: 11721169]
150 Lockridge L, Papac RJ, Perazella MA "Pamidronate-associated nephrotoxicity in a patient with Langerhans's histiocytosis." Am J Kidney Dis 40 (2002): E2. [PMID: 12087588]
151 Markowitz GS, Fine PL, Stack JI, et al. "Toxic acute tubular necrosis following treatment with zoledronate (Zometa)." Kidney Int 64 (2003): 281-289. [PMID: 12787420]
152 Osullivan TL, Akbari A, Cadnapaphornchai P "Acute renal failure associated with the administration of parenteral etidronate." Ren Fail 16 (1994): 767-73. [PMID: 7899588]
153 Product Information. Aredia (pamidronate). Novartis Pharmaceuticals, East Hanover, NJ.
154 Product Information. Boniva (ibandronate). Roche Laboratories, Nutley, NJ.
155 Product Information. Ostac (clodronate). Hoffmann-La Roche Limited, Mississauga, IA.
156 Zazgornik J, Grafinger P, Biesenbach G, Hubmann R, Fridrik M "Acute renal failure and alendronate." Nephrol Dial Transplant 12 (1997): 2797-8. [PMID: 9430905]