Details of Drug

Details of Drug

 Drug General Information (ID: D0144)
  Drug Name
Baloxavir marboxil
  Drug Type Small molecule
  Drug Synonymous
UNII-505CXM6OHG; 505CXM6OHG; Xofluza (TN); Baloxavir marboxil [INN]; Baloxavir marboxil (JAN/INN); SCHEMBL20108731; EX-A1867; HY-109025; CS-0030527
    Click to Show/Hide
  Disease Class 1E30-1E32: Influenza
  Therapeutic Class Antiviral Agents
  Structure Could Not Find 2D Structure
3D Structure 2D Structure
  Formula C27H23F2N3O7S
  InChI 1S/C27H23F2N3O7S/c1-36-27(35)39-14-38-25-19(33)8-9-31-24(25)26(34)30-10-11-37-12-21(30)32(31)23-15-6-7-18(28)22(29)17(15)13-40-20-5-3-2-4-16(20)23/h2-9,21,23H,10-14H2,1H3/t21-,23+/m1/s1
  InChIKey RZVPBGBYGMDSBG-GGAORHGYSA-N
  Canonical SMILES COC(=O)OCOC1=C2C(=O)N3CCOCC3N(N2C=CC1=O)C4C5=C(CSC6=CC=CC=C46)C(=C(C=C5)F)F
  External Link
Pubchem ID 124081896
CAS Number 1985606-14-1
TTD ID D0O5AG
INTEDE ID DR0171
VARIDT ID DR00363

Drug-Drug Interaction Network
  Sunburst Graph
AM001  Affected gastrointestinal absorption
BM003  Complex formation
  Relation Graph
 Full list of drugs interacting with Baloxavir marboxil
      Affected gastrointestinal absorption
   Complex formation Drug Num:  33
Drug ID
 
Drug Name
 Formula Pubchem ID Severity Level Interaction Detail REF
D0049
 
Aluminum hydroxide
 
AlH3O3
 
10176082 
Moderate    Inter Info   
[1]
D0125
 
Attapulgite
 
Al2H29Mg2O15Si4-
 
56842194 
Moderate    Inter Info   
[1]
D0649
 
Ferrous fumarate
 
C4H2FeO4
 
6433164 
Moderate    Inter Info   
[1]
D0650
 
Ferrous gluconate
 
C12H22FeO14
 
23616740 
Moderate    Inter Info   
[1]
D1566
 
Tetraferric tricitrate decahydrate
 
C18H32Fe4O31
 
90478690 
Moderate    Inter Info   
[2], [1]
D1722
 
Zinc acetate
 
C4H6O4Zn
 
11192 
Moderate    Inter Info   
[1]
D0235
 
Calcium acetate
 
C4H6CaO4
 
6116 
Moderate    Inter Info   
[1]
D0236
 
Calcium carbonate
 
CCaO3
 
10112 
Moderate    Inter Info   
[1]
D0238
 
Calcium citrate
 
C12H10Ca3O14
 
13136 
Moderate    Inter Info   
[1]
D0239
 
Calcium glubionate anhydrous
 
C18H32CaO19
 
64776 
Moderate    Inter Info   
[2], [1]
D0241
 
Calcium gluconate
 
C12H22CaO14
 
9290 
Moderate    Inter Info   
[1]
D0242
 
Calcium glycerophosphate
 
C3H7CaO6P
 
120096 
Moderate    Inter Info   
[1]
D0243
 
Calcium lactate
 
C6H10CaO6
 
13144 
Moderate    Inter Info   
[1]
D0244
 
Calcium Phosphate
 
Ca3O8P2
 
24456 
Moderate    Inter Info   
[2], [1]
D0332
 
Chromium picolinate
 
C18H12CrN3O6
 
151932 
Moderate    Inter Info   
[1]
D0390
 
Copper gluconate
 
C12H22CuO14
 
10692 
Moderate    Inter Info   
[1]
D0651
 
Ferrous sulfate anhydrous
 
FeO4S
 
24393 
Moderate    Inter Info   
[2], [1]
D0847
 
Iron
 
Fe
 
23925 
Moderate    Inter Info   
[2], [1]
D0849
 
Iron protein succinylate
 
NA
 
NA
Moderate    Inter Info   
[1]
D0877
 
Kaolin
 
Al2H4O9Si2
 
56841936 
Moderate    Inter Info   
[1]
D0967
 
Magaldrate
 
AlHMgO5S+2
 
3086011 
Moderate    Inter Info   
[1]
D0968
 
Magnesium carbonate
 
CMgO3
 
11029 
Moderate    Inter Info   
[1]
D0969
 
Magnesium chloride
 
Cl2H12MgO6
 
643991 
Moderate    Inter Info   
[1]
D0970
 
Magnesium citrate
 
C12H10Mg3O14
 
6099959 
Moderate    Inter Info   
[1]
D0971
 
Magnesium gluconate
 
C12H22MgO14
 
11418570 
Moderate    Inter Info   
[1]
D0972
 
Magnesium glycinate
 
C4H8MgN2O4
 
84645 
Moderate    Inter Info   
[1]
D0973
 
Magnesium hydroxide
 
H2MgO2
 
14791 
Moderate    Inter Info   
[1]
D0974
 
Magnesium oxide
 
MgO
 
14792 
Moderate    Inter Info   
[1]
D0975
 
Magnesium sulfate
 
MgO4S
 
24083 
Moderate    Inter Info   
[1]
D1456
 
Selenium
 
Se
 
6326970 
Moderate    Inter Info   
[1]
D1511
 
Sucralfate
 
C12H54Al9O55S8
 
121494085 
Moderate    Inter Info   
[1]
D1724
 
Zinc gluconate
 
C12H22O14Zn
 
443445 
Moderate    Inter Info   
[1]
D1725
 
Zinc sulfate
 
O4SZn
 
24424 
Moderate    Inter Info   
[1]
References
1 Product Information. Xofluza (baloxavir marboxil). Genentech, South San Francisco, CA.
2 Cerner Multum, Inc. "Australian Product Information.".