Details of Drug | MecDDI

Drug General Information (ID: D0060)
Drug Name		Aminocaproic acid
Drug Type		Small molecule
Drug Synonymous		6-Aminohexanoic acid; 6-aminohexanoic acid; 6-Aminocaproic acid; aminocaproic acid; 60-32-2; amicar; Epsikapron; Caprocid; Capramol; Epsamon; EACA; Caprolisin; Acepramin; Hemocaprol; Epsicapron; Respramin; Amikar; EPSILON-AMINOCAPROIC ACID; Hexanoic acid, 6-amino-; Epsilcapramin; Aminokapron; Caplamin; Acepramine; Capracid; Hemopar; Ipsilon; Afibrin; Atsemin; Hepin; Epsilon S; Aminocaproic; Capralense; epsilon-Leucine; EACS; epsilon-Norleucine; epsilcapramine; 6-Amino-n-hexanoic acid; omega-Aminocaproic acid; epsilon-Aminohexanoic acid; 6-amino-hexanoic acid; ACS; Amicar; Aminocaproate; Capranol; Caproamin; Epsicaprom; Epsilcapramine; Hemopar;Hepin; Acide aminocaproique; Acide aminocaproique [French]; Acide aminocaproque; Acido aminocaproico; Acidum aminocaproicum; Acidum aminocaproicum [Latin]; Aminocaproic Acid In Plastic Container; Aminocaproic Acids; Aminohexanoic acid; Eaca kabi; Epsilon Aminocaproic Acid; A 7824; CL 10304; CY 116; CY116; JD 177; Acide aminocaproique [INN-French]; Acido aminocaproico [DCIT,Spanish]; Acido aminocaproico [INN-Spanish]; Acidum aminocaproicum [INN-Latin]; Amicar (TN); Aminocaproic acid (USP); CL-10304; CY-116; Epsilon-Ahx; Epsilon-Aminocaproic acid; Epsilon-Aminocapronsaeure; Epsilon-Aminohexanoic acid; Epsilon-Leucine; Epsilon-Norleucine; Epsilon-aminocaproate; Epsilon-aminocapronzuur; Fullevir (TN); Kyselina omega-aminokapronova; Kyselina omega-aminokapronova [Czech]; Omega-Aminocaproic acid; Omega-Aminohexanoic acid; S04-0132; Acid, 6-Aminocaproic; Acid, 6-Aminohexanoic; Acid, epsilon-Aminocaproic; Aminocaproic acid (USP/INN); Aminocaproic acid [USAN:BAN:INN]; Aminocaproic acid [USAN:INN:BAN]; Epsilon-Aminocaproic acid (JAN); HEXANOIC ACID,6-AMINO; Epsilon-Amino-n-caproic acid; Epsilon-Amino-n-hexanoic acid; Amicar, A-amino caproic acid, A-Ahx, 6-aminohexanoic acid, Aminocaproic acid; 6 Aminocaproic Acid; 6 Aminohexanoic Acid; 6-amino-n-caproate; 6-amino-n-caproic acid; 6-aminohexanoate; 6-Amino Hexanoic Acid Click to Show/Hide
Disease Class		GA20-GA21: Bleeding disorder; NE81: Procedure injury
Therapeutic Class		Antifibrinolytic Agents
Structure
Structure		3D Structure				2D Structure
Formula		C6H13NO2
InChI		1S/C6H13NO2/c7-5-3-1-2-4-6(8)9/h1-5,7H2,(H,8,9)
InChIKey		SLXKOJJOQWFEFD-UHFFFAOYSA-N
Canonical SMILES		C(CCC(=O)O)CCN
External Link
		Pubchem ID		564
		CAS Number		60-32-2
		CHEBI ID		16586
		TTD ID		D0FD0H
		VARIDT ID		DR01014

Drug-Drug Interaction Network
Sunburst Graph		Legend Information AM006 Pharmacodynamic additive effects AM007 Pharmacodynamic antagonistic effects BM047 Additive thrombogenic effects BM085 Antagonize the effect of antithrombotic agents
Relation Graph

Full list of drugs interacting with Aminocaproic acid
Pharmacodynamic additive effects
					Additive thrombogenic effects																																																																Drug Num: 4
Drug ID															Drug Name															Formula															Pubchem ID															Severity Level															Interaction Detail													REF
D1740															Anti-inhibitor coagulant complex															NA															NA															Major															Inter Info													[1], [2], [3]
D0261															Carfilzomib															C40H57N5O7															11556711															Major															Inter Info													[4], [5], [6]
D0633															Factor IX Complex (Human)															NA															NA															Major															Inter Info													[1], [2], [3]
D1626															Tretinoin															C20H28O2															444795															Major															Inter Info													[7], [1], [8]
Pharmacodynamic antagonistic effects
					Antagonize the effect of antithrombotic agents																																																																Drug Num: 6
Drug ID															Drug Name															Formula															Pubchem ID															Severity Level															Interaction Detail													REF
D0047															Alteplase															NA															NA															Moderate															Inter Info													[1], [2], [9]
D0088															Anistreplase															NA															NA															Moderate															Inter Info													[1], [2], [9]
D1395															Reteplase															NA															NA															Moderate															Inter Info													[1], [2], [9]
D1506															Streptokinase															C11H19NO2															9815560															Moderate															Inter Info													[1], [2], [9]
D1550															Tenecteplase															NA															NA															Moderate															Inter Info													[1], [2], [9]
D1669															Urokinase															NA															NA															Moderate															Inter Info													[1], [2], [9]

References
1	Product Information. LYSTEDA (tranexamic acid). Xanodyne Pharmaceuticals Inc, Newport, KY.
2	Product Information. Cyklokapron (tranexamic acid). Pharmacia and Upjohn, Kalamazoo, MI.
3	Product Information. Amicar (aminocaproic acid). Immunex Corporation, Seattle, WA.
4	Cerner Multum, Inc. "Australian Product Information.".
5	Product Information. Kyprolis (carfilzomib). Onyx Pharmaceuticals Inc, South San Francisco, CA.
6	Cerner Multum, Inc. "UK Summary of Product Characteristics.".
7	Product Information. Vesanoid (tretinoin). Roche Laboratories, Nutley, NJ.
8	Hashimoto S, Koike T, Tatewaki W, et al. "Fatal thromboembolism in acute promyelocytic leukemia during all-trans retinoic acid therapy combined with antifibrinolytic therapy for prophylaxis of hemorrhage." Leukemia 8 (1994): 1113-5.[PMID: 8035603]
9	Product Information. Trasylol (aprotinin). Bayer, West Haven, CT.