Details of Drug Interaction

Details of Drug-Drug Interaction

 Drug General Information (ID: DDIZS5WLCF)
  Drug Name Rivastigmine Drug Info Rapacuronium Drug Info
  Drug Type Small molecule Small molecule
  Therapeutic Class Cholinesterase Inhibitors Neuromuscular Blocking Agents
  Structure

 Mechanism of Rivastigmine-Rapacuronium Interaction (Severity Level: Minor)
     Additive neuromuscular blocking effects Click to Show/Hide Mechanism Graph
Could Not Find 2D Structure
      Drug Name Rivastigmine Rapacuronium
      Mechanism Neuromuscular blocking effects Neuromuscular blocking agent
Neuronal acetylcholine receptor  Antagonist
      Key Mechanism Factor 1
Factor Name Neuronal acetylcholine receptor Structure Sequence
Protein Family Ligand-gated ion channel (TC 1.A.9) family
Protein Function
After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane.
    Click to Show/Hide
      Mechanism Description
  • Additive neuromuscular blocking effects by the combination of Rivastigmine and Rapacuronium 

References
1 Product Information. Exelon (rivastigmine) Novartis Pharmaceuticals, East Hanover, NJ.