Details of Drug-Drug Interaction
| Drug General Information (ID: DDIZJSN3A2) | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Drug Name | Oxazepam | Drug Info | Teduglutide | Drug Info | |||||
| Drug Type | Small molecule | Small molecule | |||||||
| Therapeutic Class | Anxiolytics/Sedatives/Hypnotics | Gi Agents | |||||||
| Structure | |||||||||
| Mechanism of Oxazepam-Teduglutide Interaction (Severity Level: Moderate) | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Altered absorption (Unspecific) Click to Show/Hide Mechanism Graph | |||||||||
| Drug Name | Oxazepam | Teduglutide | |||||||
| Mechanism | Absorption increased by teduglutide | Teduglutide | |||||||
| Key Mechanism Factor 1 | |||||||||
| Factor Name | Pharmacokinetic | ||||||||
| Factor Description | Alters the absorption of the drug, leading to changes in the plasma concentration of the drug and affecting the pharmacological effects. | ||||||||
| Mechanism Description |
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| Recommended Action | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Management | Monitor patients receiving concomitant oral drugs requiring titration or with a narrow therapeutic index for adverse reactions due to potential increased absorption. The dose of the concomitant drug may need to be reduced. | ||||||||
| References | |||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | Product Information. Gattex (teduglutide). NPS Pharmaceuticals, Bedminster, NJ. | ||||||||||||||||||