Drug General Information (ID: DDIXCTJDRP)
Drug Name			Fludeoxyglucose (18F)		Drug Info		Insulin degludec		Drug Info
Drug Type		Small molecule				Hormones
Therapeutic Class		Diagnostic Radiopharmaceuticals				Insulin/Antidiabetic Agents
Structure

Mechanism of Fludeoxyglucose (18F)-Insulin degludec Interaction (Severity Level: Moderate)
Interference of cell/tissue uptake Click to Show/Hide Mechanism Graph
Drug Name		Fludeoxyglucose (18F)				Insulin degludec
Mechanism		Fludeoxyglucose F18				Effect fludeoxyglucose F18 diagnostic test results
Key Mechanism Factor 1
		Factor Name		Pharmacokinetics
		Factor Description		Alters the distribution of the drug, leading to changes in the plasma concentration of the drug and affecting the pharmacological effects.
Mechanism Description		Interference of cell/tissue uptake of Fludeoxyglucose (18F) by Insulin degludec

Recommended Action
Management		Clinicians should be aware of possible diagnostic interference associated with the following medications: colony-stimulating factors may increase uptake in spleen and bone marrow glucose-induced hyperglycemia may interfere with uptake dopamine and insulin may decrease myocardial and tumor cell uptake laxative-induced intestinal muscle activity and/or irritation may increase intestinal uptake.

References
1	Cerner Multum, Inc. "Australian Product Information.".
2	Multum Information Services, Inc. Expert Review Panel.
3	Product Information. Metamucil (psyllium). Procter and Gamble Pharmaceutic, Cincinnati, OH.