Drug General Information (ID: DDIXCFQPKG)
  Drug Name Gemcitabine Drug Info Etoposide Drug Info
  Drug Type Small molecule Small molecule
  Therapeutic Class Antineoplastics Antineoplastics
  Structure

 Mechanism of Gemcitabine-Etoposide Interaction (Severity Level: Minor)
     Additive immunosuppressive effects Click to Show/Hide Mechanism Graph
Could Not Find 2D Structure
      Drug Name Gemcitabine Etoposide
      Mechanism Immunosuppressive effects Immunosuppressive effects
      Key Mechanism Factor 1
Factor Name Immunosuppressive effects
Factor Description Immunosuppression is when your immune system is not functioning as it should. The immune system is made up of cells, tissues and organs that help the body fight off infections. If the immune system is suppressed, an infection that your body was able to control may become serious or even fatal.
      Mechanism Description
  • Additive immunosuppressive effects by the combination of Gemcitabine and Etoposide 

References
1 Sacristan JA, Kennedy-Martin T, Rosell R, Cardenal F, Anton A, Lomas M, Alberola V, Massuti B, Carrato A, Minshall M. Economic evaluation in a randomized phase III clinical trial comparing gemcitabine/cisplatin and etoposide/cisplatin in non-small cell lung cancer. Lung Cancer. 2000 May;28(2):97-107.