Drug General Information (ID: DDIUYD1732)
Drug Name			Sotalol		Drug Info		Tetrofosmin		Drug Info
Drug Type		Small molecule				Small molecule
Therapeutic Class		Antiarrhythmic Agents				Diagnostic Agents
Structure

Mechanism of Sotalol-Tetrofosmin Interaction (Severity Level: Moderate)
Attenuated pharmacological effects (Unspecific) Click to Show/Hide Mechanism Graph
Drug Name		Sotalol				Tetrofosmin
Mechanism		Interfere with the diagnostic effect of tetrofosmin due to influence myocardial function and blood flow				Tetrofosmin
Key Mechanism Factor 1
		Factor Name		Pharmacodynamics
		Factor Description		Reduced pharmacological effects leading to insufficient efficacy and/or treatment failure.
Mechanism Description		Attenuated pharmacological effects of  Tetrofosmin when combined with Sotalol

Recommended Action
Management		Clinicians should consider concomitant medications that may influence myocardial function and blood flow when assessing images.

References
1	Product Information. Myoview (tetrofosmin). GE Healthcare, Princeton, NJ.