Drug General Information (ID: DDIT1G2A45)
Drug Name			Felodipine		Drug Info		Aminophylline		Drug Info
Drug Type		Small molecule				Small molecule
Therapeutic Class		Antihypertensive Agents				Bronchodilators
Structure

Mechanism of Felodipine-Aminophylline Interaction (Severity Level: Minor)
Altered absorption (Unspecific) Click to Show/Hide Mechanism Graph
Drug Name		Felodipine				Aminophylline
Mechanism		Decrease the absorption of methylxanthine				Methylxanthine
Key Mechanism Factor 1
		Factor Name		Pharmacokinetic
		Factor Description		Alters the absorption of the drug, leading to changes in the plasma concentration of the drug and affecting the pharmacological effects.
Mechanism Description		Altered absorption of Aminophylline caused by Felodipine

References
1	Bratel T, Billing B, Dahlqvist R "Felodipine reduces the absorption of theophylline in man." Eur J Clin Pharmacol 36 (1989): 481-5. [PMID: 2753066]
2	Upton RA "Pharmacokinetic interactions between theophylline and other medication (Part II)." Clin Pharmacokinet 20 (1991): 135-50. [PMID: 1709398]