Drug General Information (ID: DDIT09X1ZN)
Drug Name			Polyethylene glycol (3350 with electrolytes)		Drug Info		Fludeoxyglucose (18F)		Drug Info
Drug Type		Small molecule				Small molecule
Therapeutic Class		Laxatives				Diagnostic Radiopharmaceuticals
Structure

Mechanism of Polyethylene glycol (3350 with electrolytes)-Fludeoxyglucose (18F) Interaction (Severity Level: Moderate)
Interference of cell/tissue uptake Click to Show/Hide Mechanism Graph
Drug Name		Polyethylene glycol (3350 with electrolytes)				Fludeoxyglucose (18F)
Mechanism		Effect fludeoxyglucose F18 diagnostic test results				Fludeoxyglucose F18
Key Mechanism Factor 1
		Factor Name		Pharmacokinetics
		Factor Description		Alters the distribution of the drug, leading to changes in the plasma concentration of the drug and affecting the pharmacological effects.
Mechanism Description		Interference of cell/tissue uptake of Fludeoxyglucose (18F) by Polyethylene glycol (3350 with electrolytes)

Recommended Action
Management		Clinicians should be aware of possible diagnostic interference associated with the following medications: colony-stimulating factors may increase uptake in spleen and bone marrow glucose-induced hyperglycemia may interfere with uptake dopamine and insulin may decrease myocardial and tumor cell uptake laxative-induced intestinal muscle activity and/or irritation may increase intestinal uptake.

References
1	Cerner Multum, Inc. "Australian Product Information.".
2	Multum Information Services, Inc. Expert Review Panel.
3	Product Information. Metamucil (psyllium). Procter and Gamble Pharmaceutic, Cincinnati, OH.