Drug General Information (ID: DDIRPH36Z5)
Drug Name			Laronidase		Drug Info		Chloroquine		Drug Info
Drug Type		Protein/peptide				Small molecule
Therapeutic Class		Lysosomal Enzymes				Antimalarial Agents

Mechanism of Laronidase-Chloroquine Interaction (Severity Level: Minor)
Interference of cell/tissue uptake Click to Show/Hide Mechanism Graph
Drug Name		Laronidase				Chloroquine
Mechanism		Laronidase				Interference with the intracellular uptake of laronidase
Key Mechanism Factor 1
		Factor Name		Pharmacokinetics
		Factor Description		Alters the distribution of the drug, leading to changes in the plasma concentration of the drug and affecting the pharmacological effects.
Mechanism Description		Interference of cell/tissue uptake of Laronidase by Chloroquine

References
1	Canadian Pharmacists Association.
2	Cerner Multum, Inc. "UK Summary of Product Characteristics.".
3	EMEA. European Medicines Agency "EPARs. European Union Public Assessment Reports.".