Drug General Information (ID: DDIQAXK6PC)
  Drug Name Cefixime Drug Info Nifedipine Drug Info
  Drug Type Small molecule Small molecule
  Therapeutic Class Antibiotics Analgesics
  Structure

 Mechanism of Cefixime-Nifedipine Interaction (Severity Level: Minor)
     Altered absorption (Unspecific) Click to Show/Hide Mechanism Graph
      Drug Name Cefixime Nifedipine
      Mechanism Absorption increased by nifedipine Nifedipine
      Key Mechanism Factor 1
Factor Name Pharmacokinetic
Factor Description Alters the absorption of the drug, leading to changes in the plasma concentration of the drug and affecting the pharmacological effects.
      Mechanism Description
  • Altered absorption of Cefixime caused by Nifedipine 

References
1 Duverne C, Bouten A, Deslandes A "Modification of cefixime bioavailabity by nifedipine in humans: involvement of the dipeptide carrier system." Antimicrob Agents Chemother 36 (1992): 2462-7. [PMID: 1489189]