Drug General Information (ID: DDIPJ80WAI)
Drug Name			Omeprazole		Drug Info		Isosorbide mononitrate		Drug Info
Drug Type		Small molecule				Small molecule
Therapeutic Class		Antiulcer Agents				Vasodilator Agents
Structure

Mechanism of Omeprazole-Isosorbide mononitrate Interaction (Severity Level: Minor)
Altered absorption (Unspecific) Click to Show/Hide Mechanism Graph
Drug Name		Omeprazole				Isosorbide mononitrate
Mechanism		Inhibit the drug delivery of oral nitrates				Oral nitrates
Key Mechanism Factor 1
		Factor Name		Pharmacokinetic
		Factor Description		Alters the absorption of the drug, leading to changes in the plasma concentration of the drug and affecting the pharmacological effects.
Mechanism Description		Altered absorption of Isosorbide mononitrate caused by Omeprazole

References
1	Kajinami K, Mabuchi H "Omeprazole and diminished antianginal drug delivery." Ann Intern Med 121 (1994): 385-6. [PMID: 8042836]