Drug General Information (ID: DDIPG6RSY5)
Drug Name			Cetuximab		Drug Info		Fluorouracil		Drug Info
Drug Type		Monoclonal antibody				Small molecule
Therapeutic Class		Antineoplastics				Immunosuppressive Agents

Mechanism of Cetuximab-Fluorouracil Interaction (Severity Level: Moderate)
Increased risk of other adverse reactions (Unspecific) Click to Show/Hide Mechanism Graph
Drug Name		Cetuximab				Fluorouracil
Mechanism		Risk of myocardial ischemia				Risk of myocardial ischemia
Key Mechanism Factor 1
		Factor Name		Adverse reactions
		Factor Description		An adverse reaction is an unexpected negative reaction to a medication or treatment that happens even when it's used correctly.
Mechanism Description		Increased risk of adverse reactions by the combination of Cetuximab and Fluorouracil

Recommended Action
Management		Patients who are receiving combination treatment with cetuximab and other antineoplastic drugs should be monitored for adverse effects.

References
1	Cerner Multum, Inc. "Australian Product Information.".
2	Cerner Multum, Inc. "UK Summary of Product Characteristics.".
3	EMEA. European Medicines Agency "EPARs. European Union Public Assessment Reports.".