Drug General Information (ID: DDIOCM2UIE)
Drug Name			Iron		Drug Info		Ferric derisomaltose		Drug Info
Drug Type		Small molecule				Small molecule
Therapeutic Class		Iron Supplement				Iron Supplement
Structure

Mechanism of Iron-Ferric derisomaltose Interaction (Severity Level: Moderate)
Altered absorption (Unspecific) Click to Show/Hide Mechanism Graph
Drug Name		Iron				Ferric derisomaltose
Mechanism		Iron oral				Alters iron absorption
Key Mechanism Factor 1
		Factor Name		Pharmacokinetic
		Factor Description		Alters the absorption of the drug, leading to changes in the plasma concentration of the drug and affecting the pharmacological effects.
Mechanism Description		Altered absorption of Iron caused by Ferric derisomaltose

Recommended Action
Management		Parenteral iron preparations should not be administered concomitantly with oral iron preparations. Patients should wait at least 5 days after stopping parenteral iron therapy before taking oral iron supplements.

References
1	Product Information. Feraheme (ferumoxytol). Alza Pharmaceuticals, Mountain View, CA.
2	Product Information. INFeD (iron dextran). Schein Pharmaceuticals Inc, Florham Park, NJ.
3	Product Information. Venofer (iron sucrose) American Regent Laboratories Inc, Shirley, NY.