Drug General Information (ID: DDINJK0SBH)
Drug Name			Calcifediol		Drug Info		Mineral oil		Drug Info
Drug Type		Small molecule				Small molecule
Therapeutic Class		Vitamins				Laxatives

Mechanism of Calcifediol-Mineral oil Interaction (Severity Level: Moderate)
Altered Fat-soluble drugs absorption Click to Show/Hide Mechanism Graph
Drug Name		Calcifediol				Mineral oil
Mechanism		Fat-soluble agent				Decrease fat-soluble agent absorption
Key Mechanism Factor 1
		Factor Name		Pharmacokinetic
		Factor Description		Alters the absorption of the drug, leading to changes in the plasma concentration of the drug and affecting the pharmacological effects.
Mechanism Description		Decreased absorption of Calcifediol caused by Mineral oil

Recommended Action
Management		Consider either separating the doses by at least 3 hours, substituting mineral oil with alternative therapy or using parenteral vitamin D.

References
1	Product Information. Hectorol (doxercalciferol) Genzyme Corporation, Cambridge, MA.