Drug General Information (ID: DDIKBSIGWY)
Drug Name			Pentostatin		Drug Info		Fludarabine		Drug Info
Drug Type		Small molecule				Small molecule
Therapeutic Class		Antineoplastics				Antineoplastics
Structure

Mechanism of Pentostatin-Fludarabine Interaction (Severity Level: Major)
Increased risk of other adverse reactions (Unspecific) Click to Show/Hide Mechanism Graph
Drug Name		Pentostatin				Fludarabine
Mechanism		Pulmonary toxicity				Pulmonary toxicity
Key Mechanism Factor 1
		Factor Name		Adverse reactions
		Factor Description		An adverse reaction is an unexpected negative reaction to a medication or treatment that happens even when it's used correctly.
Mechanism Description		Increased risk of adverse reactions by the combination of Pentostatin and Fludarabine

Recommended Action
Management		Concurrent use should be avoided.

References
1	Cerner Multum, Inc. "Australian Product Information.".
2	Cerner Multum, Inc. "UK Summary of Product Characteristics.".
3	Canadian Pharmacists Association "e-CPS."