Drug General Information (ID: DDIK268IYJ)
Drug Name			Hydrocortisone		Drug Info		Vilanterol		Drug Info
Drug Type		Small molecule				Small molecule
Therapeutic Class		Antiinflammatory Agents				Bronchodilators
Structure

Mechanism of Hydrocortisone-Vilanterol Interaction (Severity Level: Minor)
Increased risk of hypokalemia Click to Show/Hide Mechanism Graph
Drug Name		Hydrocortisone				Vilanterol
Mechanism		Hypokalemia				Hypokalemia
Key Mechanism Factor 1
		Factor Name		Hypokalemia
		Factor Description		Hypokalemia is a condition in which the amount of potassium in your blood is lower than normal. If you are mildly hypokalemic, you may not have any signs or symptoms, but severe hypokalemia may have the following symptoms: fatigue, constipation, frequent or heavy urination, muscle cramps or skin tingling, muscle weakness, and a fast or irregular heartbeat.
Mechanism Description		Increased risk of hypokalemia by the combination of Hydrocortisone and Vilanterol

References
1	Cerner Multum, Inc. "Australian Product Information.".
2	Cerner Multum, Inc. "UK Summary of Product Characteristics.".
3	Product Information. Foradil (formoterol) Novartis Pharmaceuticals, East Hanover, NJ.