Drug General Information (ID: DDII1LSUWG)
Drug Name			Cetuximab		Drug Info		Oxaliplatin		Drug Info
Drug Type		Monoclonal antibody				Small molecule
Therapeutic Class		Antineoplastics				Antineoplastics

Mechanism of Cetuximab-Oxaliplatin Interaction (Severity Level: Moderate)
Additive immunosuppressive effects Click to Show/Hide Mechanism Graph
Drug Name		Cetuximab				Oxaliplatin
Mechanism		Myelosuppressive effects				Myelosuppressive effects
Key Mechanism Factor 1
		Factor Name		Immunosuppressive effects
		Factor Description		Immunosuppression is when your immune system is not functioning as it should. The immune system is made up of cells, tissues and organs that help the body fight off infections. If the immune system is suppressed, an infection that your body was able to control may become serious or even fatal.
Mechanism Description		Additive immunosuppressive effects by the combination of Cetuximab and Oxaliplatin

Recommended Action
Management		Caution is advised if cetuximab is used in combination with platinum-based chemotherapy. Patients should be monitored closely for hematologic abnormalities and infections.

References
1	Cerner Multum, Inc. "Australian Product Information.".
2	Cerner Multum, Inc. "UK Summary of Product Characteristics.".