Drug General Information (ID: DDIG87QPIK)
Drug Name			Vancomycin		Drug Info		Dobutamine		Drug Info
Drug Type		Small molecule				Small molecule
Therapeutic Class		Antiinfective Agents				Cardiotonic Agents
Structure

Mechanism of Vancomycin-Dobutamine Interaction (Severity Level: Moderate)
Increased renal excretion (Unspecific) Click to Show/Hide Mechanism Graph
Drug Name		Vancomycin				Dobutamine
Mechanism		Vancomycin				Enhance the renal clearance of vancomycin
Key Mechanism Factor 1
		Factor Name		Pharmacokinetics
		Factor Description		Alters the excretion of the drug, resulting in changes in the plasma concentration of the drug and affecting the pharmacological effects.
Mechanism Description		Increased renal excretion of Vancomycin caused by Dobutamine

Recommended Action
Management		Therapeutic drug monitoring of vancomycin serum levels is advisable during coadministration.

References
1	Cerner Multum, Inc. "UK Summary of Product Characteristics.".