Drug General Information (ID: DDIG6VZPU2)
Drug Name			Melphalan		Drug Info		Zinc gluconate		Drug Info
Drug Type		Small molecule				Small molecule
Therapeutic Class		Antineoplastics				Minerals And Electrolytes
Structure

Mechanism of Melphalan-Zinc gluconate Interaction (Severity Level: Minor)
Antagonize the effects of immunosuppressants Click to Show/Hide Mechanism Graph
Drug Name		Melphalan				Zinc gluconate
Mechanism		Immunosuppressive effects				Agents that are thought to have immunostimulant properties
Key Mechanism Factor 1
		Factor Name		Pharmacodynamics
		Factor Description		Reduced pharmacological effects leading to insufficient efficacy and/or treatment failure.
Mechanism Description		Antagonize the effect of Melphalan when combined with Zinc gluconate

References
1	Izzo AA, Ernst E "Interactions between herbal medicines and prescribed drugs: a systematic review." Drugs 61 (2001): 2163-75. [PMID: 11772128]
2	Miller LG "Herbal medicinals: selected clinical considerations focusing on known or potential drug-herb interactions." Arch Intern Med 158 (1998): 2200-11. [PMID: 9818800]
3	Pepping J "Echinacea." Am J Health Syst Pharm 56 (1999): 121-2