| Mechanism of Dexlansoprazole-Raltegravir Interaction
(Severity Level: Minor)
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Altered gastric pH
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| Drug Name |
Dexlansoprazole |
Raltegravir |
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Mechanism
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Gastric alkalinizer |
Gastric pH sensitive |
| Key Mechanism Factor 1 |
| Factor Name |
Gastric pH |
| Factor Description |
The normal pH range of gastric acid is between 1.5 and 3.5 and is highly acidic, consisting mainly of hydrochloric acid. Changes in the pH of the stomach can alter the absorption of drugs. |
| Mechanism Description |
- Decreased absorption of Raltegravir due to altered gastric pH caused by Dexlansoprazole
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