Drug General Information (ID: DDIE4IT13P)
  Drug Name Bacitracin Drug Info Vibrio cholerae CVD 103-HgR strain live antigen (live) Drug Info
  Drug Type Small molecule Vaccine
  Therapeutic Class Antibiotics Vaccines

 Mechanism of Bacitracin-Vibrio cholerae CVD 103-HgR strain live antigen (live) Interaction (Severity Level: Major)
     Antagonize the effect of vaccine/toxoid Click to Show/Hide Mechanism Graph
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      Drug Name Bacitracin Vibrio cholerae CVD 103-HgR strain live antigen (live)
      Mechanism Impairs immunomodulatory bacterial infective agent Immunomodulatory infective agent
      Key Mechanism Factor 1
Factor Name Vaccine/toxoid
Factor Description The beneficial effects of the vaccine/toxinoid may be reduced, leading to a diminished or suboptimal immune response.
      Mechanism Description
  • Antagonize the effect of Vibrio cholerae CVD 103-HgR strain live antigen (live) when combined with Bacitracin 

Recommended Action
      Management Live, attenuated cholera vaccine should not be administered during or for at least 14 days after treatment with systemic antibiotics.

References
1 Product Information. Vaxchora (cholera vaccine, live). PaxVax, Miami, FL.