Drug General Information (ID: DDIDLIKXFN)
Drug Name			Bromfenac (ophthalmic)		Drug Info		Acetylcholine		Drug Info
Drug Type		Small molecule				Small molecule
Therapeutic Class		Antiinflammatory Agents				Cardiovascular Agents
Structure

Mechanism of Bromfenac (ophthalmic)-Acetylcholine Interaction (Severity Level: Minor)
Antagonize the effect of cholinergic agents Click to Show/Hide Mechanism Graph
Drug Name		Bromfenac (ophthalmic)				Acetylcholine
Mechanism		Antagonize the miotic activity of acetylcholine				Acetylcholine
Key Mechanism Factor 1
		Factor Name		Cholinergic agents
		Factor Description		The beneficial effects of cholinergic drugs may be reduced, such as reduced efficacy in the treatment of Alzheimer's disease and exacerbation of symptoms in the treatment of myasthenia gravis.
Mechanism Description		Antagonize the effect of Bromfenac (ophthalmic) when combined with Acetylcholine

References
1	Product Information. Nevanac (nepafenac ophthalmic). Alcon Laboratories Inc, Fort Worth, TX.
2	Holmes JM, Jay WM "The effect of preoperative flurbiprofen on miosis produced by acetylcholine during cataract surgery." Am J Ophthalmol 111 (1991): 735-8