Drug General Information (ID: DDIC5F7JHZ)
  Drug Name Triamterene Drug Info Danaparoid Drug Info
  Drug Type Small molecule Small molecule
  Therapeutic Class Diuretics Anticoagulants

 Mechanism of Triamterene-Danaparoid Interaction (Severity Level: Moderate)
     Increased risk of hyperkalemia Click to Show/Hide Mechanism Graph
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      Drug Name Triamterene Danaparoid
      Mechanism Hyperkalemia Hyperkalemia
      Key Mechanism Factor 1
Factor Name Hyperkalemia
Factor Description Hyperkalemia is a condition in which the level of potassium in the blood is higher than normal. While mild cases may not produce symptoms, severe hyperkalemia can lead to fatal arrhythmias if left untreated.
      Mechanism Description
  • Increased risk of hyperkalemia by the combination of Triamterene and Danaparoid 

Recommended Action
      Management Caution is advised if potassium-sparing diuretics are used with heparin or low molecular weight heparin. Serum potassium levels and renal function should be checked regularly.

References
1 Cerner Multum, Inc. "UK Summary of Product Characteristics.".
2 Cerner Multum, Inc. "Australian Product Information.".
3 Agencia Espaola de Medicamentos y Productos Sanitarios Healthcare "Centro de informacion online de medicamentos de la AEMPS - CIMA.".