Drug General Information (ID: DDIBVY2ZTO)
Drug Name			Raloxifene		Drug Info		Diazoxide		Drug Info
Drug Type		Small molecule				Small molecule
Therapeutic Class		Hormones/Antineoplastics				Antihypertensive Agents
Structure

Mechanism of Raloxifene-Diazoxide Interaction (Severity Level: Minor)
Competitive binding of plasma proteins Click to Show/Hide Mechanism Graph
Drug Name		Raloxifene				Diazoxide
Mechanism		Competition for plasma protein binding sites				Competition for plasma protein binding sites
Key Mechanism Factor 1
		Factor Name		Plasma protein binding
		Factor Description		Plasma protein binding refers to the degree of binding of a drug to proteins in the blood, and the lower the degree of binding, the more efficiently the drug can cross cell membranes or diffuse. Plasma protein binding alters the distribution and therapeutic characteristics of the drugs.
Mechanism Description		Increased plasma concentration of Diazoxide and Raloxifene due to competitive binding of plasma proteins

References
1	Product Information. Evista (raloxifene). Lilly, Eli and Company, Indianapolis, IN.