Details of Drug-Drug Interaction
| Drug General Information (ID: DDI9YDL5HV) | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Drug Name | Sargramostim | Drug Info | Fludeoxyglucose (18F) | Drug Info | |||||
| Drug Type | Protein/peptide | Small molecule | |||||||
| Therapeutic Class | Colony Stimulating Factors | Diagnostic Radiopharmaceuticals | |||||||
| Mechanism of Sargramostim-Fludeoxyglucose (18F) Interaction (Severity Level: Moderate) | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Interference of cell/tissue uptake Click to Show/Hide Mechanism Graph | |||||||||
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| Drug Name | Sargramostim | Fludeoxyglucose (18F) | |||||||
| Mechanism | Effect fludeoxyglucose F18 diagnostic test results | Fludeoxyglucose F18 | |||||||
| Key Mechanism Factor 1 | |||||||||
| Factor Name | Pharmacokinetics | ||||||||
| Factor Description | Alters the distribution of the drug, leading to changes in the plasma concentration of the drug and affecting the pharmacological effects. | ||||||||
| Mechanism Description |
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| Recommended Action | |||||||||
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| Management | Clinicians should be aware of possible diagnostic interference associated with the following medications: colony-stimulating factors may increase uptake in spleen and bone marrow glucose-induced hyperglycemia may interfere with uptake dopamine and insulin may decrease myocardial and tumor cell uptake laxative-induced intestinal muscle activity and/or irritation may increase intestinal uptake. | ||||||||