Drug General Information (ID: DDI5IZT903)
Drug Name			Ciprofloxacin		Drug Info		Metoclopramide		Drug Info
Drug Type		Small molecule				Small molecule
Therapeutic Class		Quinolones/Antibiotics				Antiemetics
Structure

Mechanism of Ciprofloxacin-Metoclopramide Interaction (Severity Level: Minor)
Altered gastrointestinal dynamics Click to Show/Hide Mechanism Graph
Drug Name		Ciprofloxacin				Metoclopramide
Mechanism		Absorption is influenced by gastrointestinal motility				Increase gastrointestinal motility
Key Mechanism Factor 1
		Factor Name		Gastrointestinal Motility
		Factor Description		Gastrointestinal motility is an important factor in determining the absorption of orally administered drugs, and it controls the residence time of the drug in the digestive tract.
Mechanism Description		Altered absorption of Ciprofloxacin due to GI dynamics variation caused by Metoclopramide

References
1	Product Information. Cipro (ciprofloxacin). Bayer, West Haven, CT.