Drug General Information (ID: DDI531Z7TV)
Drug Name			Diclofenac (ophthalmic)		Drug Info		Loteprednol (ophthalmic)		Drug Info
Drug Type		Small molecule				Small molecule
Therapeutic Class		Nsaids/Analgesics				Ophthalmic Steroids
Structure

Mechanism of Diclofenac (ophthalmic)-Loteprednol (ophthalmic) Interaction (Severity Level: Moderate)
Increased risk of other adverse reactions (Unspecific) Click to Show/Hide Mechanism Graph
Drug Name		Diclofenac (ophthalmic)				Loteprednol (ophthalmic)
Mechanism		Slow/delay healing				Slow/delay healing
Key Mechanism Factor 1
		Factor Name		Adverse reactions
		Factor Description		An adverse reaction is an unexpected negative reaction to a medication or treatment that happens even when it's used correctly.
Mechanism Description		Increased risk of adverse reactions by the combination of Diclofenac (ophthalmic) and Loteprednol (ophthalmic)

Recommended Action
Management		The use of ophthalmic NSAIDs in combination with ophthalmic corticosteroids should be avoided unless benefits outweigh the potential risks.

References
1	Product Information. Acular (ketorolac). Allergan Inc, Irvine, CA.
2	Product Information. Nevanac (nepafenac ophthalmic). Alcon Laboratories Inc, Fort Worth, TX.
3	Product Information. Xibrom (bromfenac ophthalmic). ISTA Pharmaceuticals, Irvine, CA.