Drug General Information (ID: DDI4SWRZLI)
Drug Name			Carteolol		Drug Info		Tasimelteon		Drug Info
Drug Type		Small molecule				Small molecule
Therapeutic Class		Antihypertensive Agents				Anxiolytics/Sedatives/Hypnotics
Structure

Mechanism of Carteolol-Tasimelteon Interaction (Severity Level: Moderate)
Attenuated pharmacological effects (Unspecific) Click to Show/Hide Mechanism Graph
Drug Name		Carteolol				Tasimelteon
Mechanism		Reduce therapeutic efficacy of tasimelteon				Tasimelteon
Key Mechanism Factor 1
		Factor Name		Pharmacodynamics
		Factor Description		Reduced pharmacological effects leading to insufficient efficacy and/or treatment failure.
Mechanism Description		Attenuated pharmacological effects of  Carteolol when combined with Tasimelteon

Recommended Action
Management		Product labeling for tasimelteon suggests avoiding the nighttime administration of beta-blockers.

References
1	Product Information. Hetlioz (tasimelteon). Vanda Pharmaceuticals Inc, Rockville, MD.