Drug General Information (ID: DDI4AD0OEL)
Drug Name			Meticillin		Drug Info		Vibrio cholerae CVD 103-HgR strain live antigen (live)		Drug Info
Drug Type		Small molecule				Vaccine
Therapeutic Class		Antibiotics				Vaccines

Mechanism of Meticillin-Vibrio cholerae CVD 103-HgR strain live antigen (live) Interaction (Severity Level: Major)
Antagonize the effect of vaccine/toxoid Click to Show/Hide Mechanism Graph
Drug Name		Meticillin				Vibrio cholerae CVD 103-HgR strain live antigen (live)
Mechanism		Impairs immunomodulatory bacterial infective agent				Immunomodulatory infective agent
Key Mechanism Factor 1
		Factor Name		Vaccine/toxoid
		Factor Description		The beneficial effects of the vaccine/toxinoid may be reduced, leading to a diminished or suboptimal immune response.
Mechanism Description		Antagonize the effect of Vibrio cholerae CVD 103-HgR strain live antigen (live) when combined with Meticillin

Recommended Action
Management		Live, attenuated cholera vaccine should not be administered during or for at least 14 days after treatment with systemic antibiotics.

References
1	Product Information. Vaxchora (cholera vaccine, live). PaxVax, Miami, FL.