Drug General Information (ID: DDI0R1DG92)
Drug Name			Bleomycin		Drug Info		Brentuximab vedotin		Drug Info
Drug Type		Small molecule				Monoclonal antibody
Therapeutic Class		Antineoplastics				Antineoplastics

Mechanism of Bleomycin-Brentuximab vedotin Interaction (Severity Level: Major)
Increased risk of other adverse reactions (Unspecific) Click to Show/Hide Mechanism Graph
Drug Name		Bleomycin				Brentuximab vedotin
Mechanism		Pulmonary toxicity				Pulmonary toxicity
Key Mechanism Factor 1
		Factor Name		Adverse reactions
		Factor Description		An adverse reaction is an unexpected negative reaction to a medication or treatment that happens even when it's used correctly.
Mechanism Description		Increased risk of adverse reactions by the combination of Bleomycin and Brentuximab vedotin

Recommended Action
Management		Concomitant use of brentuximab and bleomycin is considered contraindicated.

References
1	Product Information. Adcetris (brentuximab vedotin). Seattle Genetics Inc, Bothell, WA.