Drug General Information (ID: DDI0QIT6SL)
  Drug Name Sulfadoxine Drug Info Aminobenzoic acid Drug Info
  Drug Type Small molecule Small molecule
  Therapeutic Class Antimalarial Agents Vitamins
  Structure

 Mechanism of Sulfadoxine-Aminobenzoic acid Interaction (Severity Level: Major)
     Attenuated pharmacological effects (Unspecific) Click to Show/Hide Mechanism Graph
      Drug Name Sulfadoxine Aminobenzoic acid
      Mechanism Sulfonamides Antagonize the antibacterial effects of sulfonamides
      Key Mechanism Factor 1
Factor Name Pharmacodynamics
Factor Description Reduced pharmacological effects leading to insufficient efficacy and/or treatment failure.
      Mechanism Description
  • Attenuated pharmacological effects of  Sulfadoxine when combined with Aminobenzoic acid 

Recommended Action
      Management The manufacturer considers concomitant use contraindicated.

References
1 Product Information. Potaba (potassium aminobenzoate). Glenwood Inc, Englewood, NJ.