Details of Drug

Details of Drug

 Drug General Information (ID: D1898)
  Drug Name
Tazobactam
  Drug Type Small molecule
  Drug Synonymous
TAZ; CL298741; YTR830H; CL-298741; Piprataz (TN); YTR-830H; Tazobactam (JAN/USAN/INN); (2S,3S,5R)-3-methyl-4,4,7-trioxo-3-(triazol-1-ylmethyl)-4; (2S,3S,5R)-3-methyl-7-oxo-3-(1H-1,2,3-triazol-1-ylmethyl)-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid 4,4-dioxide
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  Disease Class 1A00-1C4Z: Bacterial infection
  Therapeutic Class Antiinfective Agents
  Structure Could Not Find 2D Structure
3D Structure 2D Structure
  Formula C10H12N4O5S
  InChI 1S/C10H12N4O5S/c1-10(5-13-3-2-11-12-13)8(9(16)17)14-6(15)4-7(14)20(10,18)19/h2-3,7-8H,4-5H2,1H3,(H,16,17)/t7-,8+,10+/m1/s1
  InChIKey LPQZKKCYTLCDGQ-WEDXCCLWSA-N
  Canonical SMILES CC1(C(N2C(S1(=O)=O)CC2=O)C(=O)O)CN3C=CN=N3
  External Link
Pubchem ID 123630
CAS Number CAS 89786-04-9
CHEBI ID CHEBI:9421
TTD ID D0QQ7D
INTEDE ID DR2453

Drug-Drug Interaction Network
  Sunburst Graph
AM002  Affected cellular transport
AM005  Affected excretion pathways
BM012  Competitive inhibition of transporters
BM028  Competitive inhibition of renal tubular secretion
  Relation Graph
 Full list of drugs interacting with Tazobactam
      Affected cellular transport
   Competitive inhibition of transporters Drug Num:  1
Drug ID
 
Drug Name
 Formula Pubchem ID Severity Level Interaction Detail REF
D1341
 
Probenecid
 
C13H19NO4S
 
4911 
Moderate    Inter Info   
[2], [3]
      Affected excretion pathways
   Competitive inhibition of renal tubular secretion Drug Num:  1
Drug ID
 
Drug Name
 Formula Pubchem ID Severity Level Interaction Detail REF
D0576
 
Entecavir
 
C12H15N5O3
 
135398508 
Moderate    Inter Info   
[1]
References
1 Product Information. Baraclude (entecavir). Bristol-Myers Squibb, Princeton, NJ.
2 Product Information. Zosyn (piperacillin-tazobactam). Lederle Laboratories, Wayne, NJ.
3 Product Information. Zerbaxa (ceftolozane-tazobactam). Cubist Pharmaceuticals Inc, Lexington, MA.