Details of Drug

Drug General Information (ID: D1880)
Drug Name	Rimexolone (ophthalmic)
Drug Type	Small molecule
Drug Synonymous	Rimexolone (sustained release intra-articular steroid suspension, Plexis, arthritis) Click to Show/Hide
Disease Class	FA20: Rheumatoid arthritis
Therapeutic Class	Ophthalmic Steroids
Structure
Structure	3D Structure		2D Structure
Formula	C24H34O3
InChI	1S/C24H34O3/c1-6-20(27)24(5)14(2)11-18-17-8-7-15-12-16(25)9-10-22(15,3)21(17)19(26)13-23(18,24)4/h9-10,12,14,17-19,21,26H,6-8,11,13H2,1-5H3/t14-,17+,18+,19+,21-,22+,23+,24-/m1/s1
InChIKey	QTTRZHGPGKRAFB-OOKHYKNYSA-N
Canonical SMILES	CCC(=O)C1(C(CC2C1(CC(C3C2CCC4=CC(=O)C=CC34C)O)C)C)C
External Link
	Pubchem ID	5311412
	CAS Number	CAS 49697-38-3
	CHEBI ID	CHEBI:135566
	TTD ID	D0D2TN
	INTEDE ID	DR1426

Drug-Drug Interaction Network
Sunburst Graph		Legend Information AM007 Pharmacodynamic antagonistic effects BM100 Antagonize the effect of vaccine/toxoid
Relation Graph

Full list of drugs interacting with Rimexolone (ophthalmic)
Pharmacodynamic antagonistic effects
	Antagonize the effect of vaccine/toxoid					Drug Num: 1
Drug ID		Drug Name	Formula	Pubchem ID	Severity Level		Interaction Detail	REF
D1890		Smallpox (Vaccinia) Vaccine, Live	NA	NA	Major		Inter Info	[1], [2], [3]

References
1	CDC. Centers for Disease Control and Prevention/ "Recommendations of the advisory committtee on immunization practices (ACIP): use of vaccines and immune globulins in persons with altered immunocompetence." MMWR Morb Mortal Wkly Rep 42(RR-04) (1993): 1-18. [PMID: 20300058]
2	Product Information. Dryvax (smallpox vaccine). Wyeth-Ayerst Laboratories, Philadelphia, PA.
3	CDC. Centers for Disease Control and Prevention "Clinical guidance for smallpox vaccine use in a postevent vaccination program.".