Details of Drug

Drug General Information (ID: D1861)
Drug Name	Pegvaliase
Drug Type	Protein/peptide
Drug Synonymous	BMN 165; Pegvaliase [INN]; UNII-N6UAH27EUV; N6UAH27EUV Click to Show/Hide
Disease Class	5C50: Metabolism inborn error
Therapeutic Class	Metabolic Agents
Structure
Structure	3D Structure		2D Structure
Formula	C15H30N2O5
InChI	1S/C15H30N2O5/c1-21-11-12-22-10-6-2-3-8-14(18)17-9-5-4-7-13(16)15(19)20/h13H,2-12,16H2,1H3,(H,17,18)(H,19,20)/t13-/m0/s1
InChIKey	NPOCDVAOUKODSQ-ZDUSSCGKSA-N
Canonical SMILES	COCCOCCCCCC(=O)NCCCCC(C(=O)O)N
External Link
	Pubchem ID	86278362
	CAS Number	CAS 1585984-95-7
	TTD ID	D0T8HZ

Drug-Drug Interaction Network
Sunburst Graph		Legend Information AM006 Pharmacodynamic additive effects BM048 Increased risk of angioedema/anaphylactoid reactions
Relation Graph

Full list of drugs interacting with Pegvaliase
Pharmacodynamic additive effects
	Increased risk of angioedema/anaphylactoid reactions					Drug Num: 16
Drug ID		Drug Name	Formula	Pubchem ID	Severity Level		Interaction Detail	REF
D0090		Antihemophilic factor, human recombinant	NA	NA	Moderate		Inter Info	[1]
D0304		Certolizumab pegol	NA	NA	Moderate		Inter Info	[1]
D0529		Doxorubicin (liposomal)	C27H29NO11	31703	Moderate		Inter Info	[1]
D0990		Medroxyprogesterone acetate	C24H34O4	6279	Moderate		Inter Info	[1]
D1104		Naloxegol	C34H53NO11	56959087	Moderate		Inter Info	[1]
D1858		Pegademase	NA	NA	Moderate		Inter Info	[1]
D1859		Pegaptanib (ophthalmic)	C22H44N3O10P	56603655	Moderate		Inter Info	[1]
D1234		Pegaspargase	C14H19NO	436058	Moderate		Inter Info	[1]
D1235		Pegfilgrastim	C27H46N4O19	70683024	Moderate		Inter Info	[1]
D1236		Peginesatide	NA	NA	Moderate		Inter Info	[1]
D1237		Peginterferon alfa-2a	NA	NA	Moderate		Inter Info	[1]
D1238		Peginterferon alfa-2b	NA	NA	Moderate		Inter Info	[1]
D1239		Peginterferon beta-1a	NA	NA	Moderate		Inter Info	[1]
D1860		Pegloticase	NA	NA	Moderate		Inter Info	[1]
D0371		Coagulation Factor IX Human	NA	NA	Moderate		Inter Info	[1]
D1862		Pegvisomant	NA	NA	Moderate		Inter Info	[1]

References
1	Product Information. Palynziq (pegvaliase). BioMarin Pharmaceutical Inc, Novato, CA.