Details of Drug

Details of Drug

 Drug General Information (ID: D1859)
  Drug Name
Pegaptanib (ophthalmic)
  Drug Type Aptamer
  Drug Synonymous
Macugen (TN); Pegaptanib Octasodium; Pegaptanib sodium; EYE 001; NX 1838; NX1838
    Click to Show/Hide
  Disease Class 9B71: Retinopathy
  Therapeutic Class Antiangiogenic Agents
  Structure Could Not Find 2D Structure
3D Structure 2D Structure
  Formula C22H44N3O10P
  InChI InChI=1S/C22H44N3O10P/c1-31-15-17-33-21(27)24-13-9-7-11-19(25-22(28)34-18-16-32-2)20(26)23-12-8-5-4-6-10-14-35-36(3,29)30/h19H,4-18H2,1-3H3,(H,23,26)(H,24,27)(H,25,28)(H,29,30)/t19-/m0/s1
  InChIKey WLCZTRVUXYALDD-IBGZPJMESA-N
  Canonical SMILES COCCOC(=O)NCCCCC(C(=O)NCCCCCCCOP(=O)(C)O)NC(=O)OCCOC
  External Link
Pubchem ID 56603655
TTD ID D0UF9W

Drug-Drug Interaction Network
  Sunburst Graph
AM006  Pharmacodynamic additive effects
AM007  Pharmacodynamic antagonistic effects
BM048  Increased risk of angioedema/anaphylactoid reactions
BM107  Attenuated pharmacological effects (Unspecific)
  Relation Graph
 Full list of drugs interacting with Pegaptanib (ophthalmic)
      Pharmacodynamic additive effects
   Increased risk of angioedema/anaphylactoid reactions Drug Num:  1
Drug ID
 
Drug Name
 Formula Pubchem ID Severity Level Interaction Detail REF
D1861
 
Pegvaliase
 
C15H30N2O5
 
86278362 
Moderate    Inter Info   
[2]
      Pharmacodynamic antagonistic effects
   Attenuated pharmacological effects (Unspecific) Drug Num:  1
Drug ID
 
Drug Name
 Formula Pubchem ID Severity Level Interaction Detail REF
D1860
 
Pegloticase
 
NA
 
NA
Moderate    Inter Info   
[1]
References
1 Product Information. Krystexxa (pegloticase). Savient Pharmaceuticals, East Brunswick, NJ.
2 Product Information. Palynziq (pegvaliase). BioMarin Pharmaceutical Inc, Novato, CA.