Details of Drug

Details of Drug

 Drug General Information (ID: D1852)
  Drug Name
Oxybuprocaine (ophthalmic)
  Drug Type Small molecule
  Drug Synonymous
Benoxil; Benoxinate; Butoxyaminobenzoyldiethylaminoethanol; Butoxyprocaine; Conjucain; Dorsacain; Novescine; Novesinol; Oxibuprocaina; Oxibuprocainum; Oxibuprokain; Oxybucaine; Oxybuprocainum; Oxyriprocaine; Prescaina; Benoxinate hydrochloride; Monofree oxybuprocaine; Oxybuprocaine HCL; Oxybuprocaine hydrochloride; S 749;Monofree oxybuprocaine (TN); Novesin (TN); Novesine (TN); Oxibuprocaina [INN-Spanish]; Oxybuprocaine (INN); Oxybuprocaine [INN:BAN]; Oxybuprocainum [INN-Latin]; Diethylaminoethyl-4-amino-3-butoxybenzoate; BENZOIC ACID, 4-AMINO-3-BUTOXY-, 2-(DIETHYLAMINO)ETHYL ESTER; Benzoic acid, 4-amino-3-butoxy-, 2-(diethylamino)ethyl ester (7CI,8CI,9CI); 2-(Diethylamino)ethyl 4-amino-3-butoxybenzoate; 2-(diethylamino)ethyl 4-amino-3-n-butoxybenzoate; 2-Diethylaminoethyl 4-amino-3-butoxybenzoate; 3-Butoxy-4-aminobenzoic acid 2-(diethylamino)ethyl ester; 3-Butoxy-4-aminobenzoic acid 2-diethylaminoethyl ester; 4-Amino-3-butoxy-2-(diethylamino)ethyl ester benzoic acid; 4-Amino-3-butoxy-benzoic acid 2-diethylamino-ethyl ester; 4-Amino-3-butoxybenzoic acid 2-(diethylamino)ethyl ester; 4-Amino-3-butoxybenzoicacid 2-diethylaminoethyl ester; 4-Amino-3-n-butoxy-benzoesaeure-diaethylaminoaethylester; 4-Amino-3-n-butoxy-benzoesaeure-diaethylaminoaethylester [German]
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  Disease Class 9A76-9A78: Corneal disease
  Therapeutic Class Anesthetics
  Structure Could Not Find 2D Structure
3D Structure 2D Structure
  Formula C17H28N2O3
  InChI 1S/C17H28N2O3/c1-4-7-11-21-16-13-14(8-9-15(16)18)17(20)22-12-10-19(5-2)6-3/h8-9,13H,4-7,10-12,18H2,1-3H3
  InChIKey CMHHMUWAYWTMGS-UHFFFAOYSA-N
  Canonical SMILES CCCCOC1=C(C=CC(=C1)C(=O)OCCN(CC)CC)N
  External Link
Pubchem ID 4633
CAS Number CAS 99-43-4
CHEBI ID CHEBI:309594
TTD ID D0H2SY

Drug-Drug Interaction Network
  Sunburst Graph
AM006  Pharmacodynamic additive effects
BM071  Increased risk of methemoglobinemia
  Relation Graph
 Full list of drugs interacting with Oxybuprocaine (ophthalmic)
      Pharmacodynamic additive effects
   Increased risk of methemoglobinemia Drug Num:  35
Drug ID
 
Drug Name
 Formula Pubchem ID Severity Level Interaction Detail REF
D0011
 
Acetaminophen
 
C8H9NO2
 
1983 
Moderate    Inter Info   
[1], [2], [3]
D0065
 
Aminosalicylic acid
 
C7H7NO3
 
4649 
Moderate    Inter Info   
[1], [2], [3]
D0218
 
Bupivacaine
 
C18H28N2O
 
2474 
Moderate    Inter Info   
[1], [2], [3]
D1752
 
Bupivacaine (liposome)
 
C18H28N2O
 
2474 
Moderate    Inter Info   
[1], [2], [3]
D0320
 
Chloroquine
 
C18H26ClN3
 
2719 
Moderate    Inter Info   
[1], [2], [3]
D0419
 
Dapsone
 
C12H12N2O2S
 
2955 
Moderate    Inter Info   
[1], [2], [3]
D0420
 
Dapsone (topical)
 
C12H12N2O2S
 
2955 
Moderate    Inter Info   
[1], [2], [3]
D0682
 
Flutamide
 
C11H11F3N2O3
 
3397 
Moderate    Inter Info   
[1], [2], [3]
D0861
 
Isosorbide dinitrate
 
C6H8N2O8
 
6883 
Moderate    Inter Info   
[1], [2], [3]
D0927
 
Lidocaine
 
C14H22N2O
 
3676 
Moderate    Inter Info   
[1], [2], [3]
D1144
 
Nitric Oxide
 
NO
 
145068 
Moderate    Inter Info   
[1], [2], [3]
D1146
 
Nitroglycerin
 
C3H5N3O9
 
4510 
Moderate    Inter Info   
[1], [2], [3]
D1147
 
Nitroprusside
 
C5FeN6O
 
11953891 
Moderate    Inter Info   
[1], [2], [3]
D0083
 
Amyl Nitrite
 
C5H11NO2
 
10026 
Moderate    Inter Info   
[1], [2], [3]
D0110
 
Articaine
 
C13H20N2O3S
 
32170 
Moderate    Inter Info   
[1], [2], [3]
D0319
 
Chloroprocaine
 
C13H19ClN2O2
 
8612 
Moderate    Inter Info   
[1], [2], [3]
D0622
 
Etidocaine
 
C17H28N2O
 
37497 
Moderate    Inter Info   
[1], [2], [3]
D0860
 
Isosorbide
 
C6H10O4
 
12597 
Moderate    Inter Info   
[1], [2], [3]
D0862
 
Isosorbide mononitrate
 
C6H9NO6
 
27661 
Moderate    Inter Info   
[1], [2], [3]
D0916
 
Levobupivacaine
 
C18H28N2O
 
92253 
Moderate    Inter Info   
[1], [2], [3]
D1004
 
Mepivacaine
 
C15H22N2O
 
4062 
Moderate    Inter Info   
[1], [2], [3]
D1261
 
Phenazopyridine
 
C11H11N5
 
4756 
Moderate    Inter Info   
[1], [2], [3]
D1265
 
Phenobarbital
 
C12H12N2O3
 
4763 
Moderate    Inter Info   
[1], [2], [3]
D1339
 
Primaquine
 
C15H21N3O
 
4908 
Moderate    Inter Info   
[1], [2], [3]
D1468
 
Silver nitrate (ophthalmic)
 
AgNO3
 
24470 
Moderate    Inter Info   
[1], [2], [3]
D1469
 
Silver nitrate (topical)
 
AgNO3
 
24470 
Moderate    Inter Info   
[1], [2], [3]
D1470
 
Silver sulfadiazine (topical)
 
C10H9AgN4O2S
 
441244 
Moderate    Inter Info   
[1], [2], [3]
D1530
 
Tafenoquine
 
C24H28F3N3O3
 
115358 
Moderate    Inter Info   
[1], [2], [3]
D1561
 
Tetracaine
 
C15H24N2O2
 
5411 
Moderate    Inter Info   
[1], [2], [3]
D1283
 
Phenytoin
 
C15H12N2O2
 
1775 
Moderate    Inter Info   
[1], [2], [3]
D1344
 
Procaine
 
C13H20N2O2
 
4914 
Moderate    Inter Info   
[1], [2], [3]
D1386
 
Rasburicase
 
NA
 
NA
Moderate    Inter Info   
[1], [2], [3]
D1428
 
Ropivacaine
 
C17H26N2O
 
175805 
Moderate    Inter Info   
[1], [2], [3]
D1515
 
Sulfamethizole
 
C9H10N4O2S2
 
5328 
Moderate    Inter Info   
[1], [2], [3]
D1519
 
Sulfisoxazole
 
C11H13N3O3S
 
5344 
Moderate    Inter Info   
[1], [2], [3]
References
1 Cerner Multum, Inc. "UK Summary of Product Characteristics.".
2 Guay J "Methemoglobinemia related to local anesthetics: a summary of 242 episodes." Anesth Analg 108 (2009): 837-45. [PMID: 19224791]
3 Product Information. Hurricaine (benzocaine topical). Beutlich, Waukegan, IL.