Details of Drug

Drug General Information (ID: D1841)
Drug Name	Medrysone (ophthalmic)
Drug Type	Small molecule
Drug Synonymous	Hydroxymesterone; Medrifar; Medritonic; Medrocort; Visudrisone; Medrysone (USAN); U-8471; (6S,8S,9S,10R,11S,13S,14S,17S)-17-acetyl-11-hydroxy-6,10,13-trimethyl-1,2,6,7,8,9,11,12,14,15,16,17-dodecahydrocyclopenta[a]phenanthren-3-one; 11.beta.-Hydroxy-6.alpha.-methylpregn-4-ene-3,20-dione; 11.beta.-Hydroxy-6.alpha.-methylprogesterone; 11beta-Hydroxy-6alpha-methyl-4-pregnene-3,20-dione; 11beta-Hydroxy-6alpha-methylpregn-4-ene-3,20-dione; 6.alpha.-Methyl-11.beta.-hydroxyprogesterone Click to Show/Hide
Disease Class	9A02: Eyelid inflammatory disorder
Therapeutic Class	Topical Glucocorticoids
Structure
Structure	3D Structure		2D Structure
Formula	C22H32O3
InChI	1S/C22H32O3/c1-12-9-15-17-6-5-16(13(2)23)22(17,4)11-19(25)20(15)21(3)8-7-14(24)10-18(12)21/h10,12,15-17,19-20,25H,5-9,11H2,1-4H3/t12-,15-,16+,17-,19-,20+,21-,22+/m0/s1
InChIKey	GZENKSODFLBBHQ-ILSZZQPISA-N
Canonical SMILES	CC1CC2C3CCC(C3(CC(C2C4(C1=CC(=O)CC4)C)O)C)C(=O)C
External Link
	Pubchem ID	247839
	CAS Number	CAS 2668-66-8
	CHEBI ID	CHEBI:34829
	TTD ID	D04SFH
	INTEDE ID	DR1013

Drug-Drug Interaction Network
Sunburst Graph		Legend Information AM007 Pharmacodynamic antagonistic effects BM100 Antagonize the effect of vaccine/toxoid
Relation Graph

Full list of drugs interacting with Medrysone (ophthalmic)
Pharmacodynamic antagonistic effects
	Antagonize the effect of vaccine/toxoid					Drug Num: 1
Drug ID		Drug Name	Formula	Pubchem ID	Severity Level		Interaction Detail	REF
D1890		Smallpox (Vaccinia) Vaccine, Live	NA	NA	Major		Inter Info	[1], [2], [3]

References
1	CDC. Centers for Disease Control and Prevention/ "Recommendations of the advisory committtee on immunization practices (ACIP): use of vaccines and immune globulins in persons with altered immunocompetence." MMWR Morb Mortal Wkly Rep 42(RR-04) (1993): 1-18. [PMID: 20300058]
2	Product Information. Dryvax (smallpox vaccine). Wyeth-Ayerst Laboratories, Philadelphia, PA.
3	CDC. Centers for Disease Control and Prevention "Clinical guidance for smallpox vaccine use in a postevent vaccination program.".