Details of Drug

Details of Drug

 Drug General Information (ID: D1815)
  Drug Name
Icosapent
  Drug Type Small molecule
  Drug Synonymous
Eicosapentaenoic acid|Timnodonic acid|Icosapent|10417-94-4|Icosapentaenoic acid|EPA|cis-5,8,11,14,17-Eicosapentaenoic acid|5,8,11,14,17-EICOSAPENTAENOIC ACID|(5Z,8Z,11Z,14Z,17Z)-icosa-5,8,11,14,17-pentaenoic acid|Icosapento|Icosapentum|5Z,8Z,11Z,14Z,17Z-Eicosapentaenoic acid|(all-Z)-5,8,11,14,17-Eicosapentaenoic acid|UNII-AAN7QOV9EA|eicosapentaenoate|(5Z,8Z,11Z,14Z,17Z)-5,8,11,14,17-eicosapentaenoic acid|Icosapent [INN]|(5Z,8Z,11Z,14Z,17Z)-Eicosapentaenoic acid|5,8,11,14,17-Icosapentaenoic acid|CCRIS 3279|AAN7QOV9EA|(5Z,8Z,11Z,14Z,17Z)-Icosapentaenoic acid|Omega-3-Carboxylic Acids|CHEMBL460026|(5Z,8Z,11Z,14Z,17Z)-Eicosapentaenoate|all-cis-5,8,11,14,17-icosapentaenoic acid|CHEBI:28364|all-cis-icosa-5,8,11,14,17-pentaenoic acid|Icosapent (INN)|cis-Delta(5,8,11,14,17)-eicosapentaenoic acid|5,8,11,14,17-Eicosapentaenoic acid, (all-Z)-|Icosapentaenoate|(all-Z)-delta5,8,11,14,17-Eicosapentaenoic acid|C20:5n-3,6,9,12,15|MFCD00065716|cis-5,8,11,14,17-EPA|NCGC00161344-03|EICOSAPENTAENOIC ACID (20:5 n-3)|all-cis-5,8,11,14,17-eicosapentaenoic acid|Miraxion|Eicosapentanoic acid|Eye Q|Eye-Q|5,8,11,14,17-Eicosapentaenoic acid, (5Z,8Z,11Z,14Z,17Z)-|EPA [drug]|Icosapentum [INN-Latin]|Icosapento [INN-Spanish]|(5Z,8Z,11Z,14Z,17Z)-icosapentaenoate|Timnodonate|3gwx|FA 20:5|all cis-5,8,11,14,17-Eicosapentaenoic Acid|Ropufa 70|Incromega e 7010sr|all-cis-icosapentaenoate|all-cis-icosapentaenoic acid|DSSTox_CID_21023|DSSTox_RID_79612|DSSTox_GSID_41023|SCHEMBL20469|BSPBio_001328|EPA 45G|BML3-B01|GTPL3362|DTXSID9041023|HMS1361C10|HMS1791C10|HMS1989C10|HMS3402C10|HMS3649D19|All-cis-fatty acid 20:5 omega-3|HY-B0660|ZINC4474603|5,8,11,14,17-Icosapentaenoate|Eicosapentaenoic acid (c20:5 n3)|Tox21_111991|1755AH|5,8,11,14,17-Eicosapentaenoate|BDBM50242349|LMFA01030759|s6476|AKOS027470327|CCG-207957|CCG-208136|DB00159|cis-5,8,11,14,17-eicosapentaenoate|IDI1_033798|NCGC00161344-01|NCGC00161344-02|NCGC00161344-04|NCGC00161344-07|5Z,8Z,11Z,14Z,17Z-Eicosapentaenoate|AC-31072|AS-53730|C20:5 (n-3)|CAS-10417-94-4|E0441|5,8,11,14,17-Eicosapentaenoic acid (6CI)|all cis-5,8,11,14,17-Icosapentaenoic Acid|C06428|D08061|P16966|(all-cis)-5,8,11,14,17-Eicosapentaenoic acid|L001256|Q409990|SR-01000946647|J-001125|SR-01000946647-1|z,z,z,z,z-eicosa-5,8,11,14,17-pentaenoic acid|(Z,Z,Z,Z,Z)-5,8,11,14,17-eicosapentaenoic acid|BRD-K47192521-001-02-1|cis-5,8,11,14,17-Eicosapentaenoic acid, >=99%|7F8BF016-B146-4F72-A52E-B9298BA3A9AB|C20H30O2 (cis-5,8,11,14,17-eicosapentaenoic acid)|Eicosapentaenoic acid, 5,8,11,14,17-(Z,Z,Z,Z,Z)-|5,8,11,14,17-Eicosapentaenoic acid, (all-Z)- (8CI)|cis-5,8,11,14,17-Eicosapentaenoic acid, >=85%, liquid|UNII-317SQ4W8IJ component JAZBEHYOTPTENJ-JLNKQSITSA-N|UNII-71M78END5S component JAZBEHYOTPTENJ-JLNKQSITSA-N|UNII-9B22238JYI component JAZBEHYOTPTENJ-JLNKQSITSA-N|UNII-F85N2YHE4E component JAZBEHYOTPTENJ-JLNKQSITSA-N|cis-5,8,11,14,17-Eicosapentaenoic acid, analytical standard|Eicosa-5Z,8Z,11Z,14Z,17Z-pentaenoic Acid (20:5, n-3)|(5Z,8Z,11 Z,14Z,17Z)-icosa-5,8,11,14,17-pentaenoic acid|(5Z,8Z,11Z,14Z,17Z)-eicosa-5,8,11,14,17-pentaenoic acid|cis, cis, cis, cis, cis-eicosa-5,8,11,14,17-pentaenoic acid|5,8,11,14,17-Eicosapentaenoic acid, (5Z,8Z,11Z,14Z,17Z)- (9CI)|cis-5,8,11,14,17-Eicosapentaenoic acid, 500 mug/mL in ethanol, certified reference material
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  Disease Class 3B14: Inherited coagulation factor deficiency; 5C80: Hyper-lipoproteinaemia
  Therapeutic Class Dietary Supplement
  Structure Could Not Find 2D Structure
3D Structure 2D Structure
  Formula C20H30O2
  InChI 1S/C20H30O2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-20(21)22/h3-4,6-7,9-10,12-13,15-16H,2,5,8,11,14,17-19H2,1H3,(H,21,22)/b4-3-,7-6-,10-9-,13-12-,16-15-
  InChIKey JAZBEHYOTPTENJ-JLNKQSITSA-N
  Canonical SMILES CCC=CCC=CCC=CCC=CCC=CCCCC(=O)O
  External Link
Pubchem ID 446284
CAS Number CAS 10417-94-4
CHEBI ID CHEBI:28364
TTD ID D0G2MW
INTEDE ID DR1991

Drug-Drug Interaction Network
  Sunburst Graph
AM006  Pharmacodynamic additive effects
BM050  Increased risk of bleeding
  Relation Graph
 Full list of drugs interacting with Icosapent
      Pharmacodynamic additive effects
   Increased risk of bleeding Drug Num:  71
Drug ID
 
Drug Name
 Formula Pubchem ID Severity Level Interaction Detail REF
D0005
 
Abciximab
 
NA
 
NA
Moderate    Inter Info   
[1], [2], [3]
D0047
 
Alteplase
 
NA
 
NA
Moderate    Inter Info   
[1], [2], [3]
D0088
 
Anistreplase
 
NA
 
NA
Moderate    Inter Info   
[1], [2], [3]
D0189
 
Bivalirudin
 
C98H138N24O33
 
16129704 
Moderate    Inter Info   
[1], [2], [3]
D0537
 
Drotrecogin alfa
 
NA
 
NA
Moderate    Inter Info   
[1], [2], [3]
D0588
 
Eptifibatide
 
C35H49N11O9S2
 
448812 
Moderate    Inter Info   
[1], [2], [3]
D0017
 
Acetylsalicylic acid
 
C9H8O4
 
2244 
Moderate    Inter Info   
[1], [2], [3]
D0084
 
Anagrelide
 
C10H7Cl2N3O
 
135409400 
Moderate    Inter Info   
[1], [2], [3]
D0087
 
Anisindione
 
C16H12O3
 
2197 
Moderate    Inter Info   
[1], [2], [3]
D0092
 
Antithrombin Alfa
 
NA
 
NA
Moderate    Inter Info   
[1], [2], [3]
D0093
 
Antithrombin III human
 
NA
 
NA
Moderate    Inter Info   
[1], [2], [3]
D0096
 
Apixaban
 
C25H25N5O4
 
10182969 
Moderate    Inter Info   
[1], [2], [3]
D0102
 
Ardeparin
 
C26H42N2O37S5
 
772 
Moderate    Inter Info   
[1], [2], [3]
D0104
 
Argatroban
 
C23H36N6O5S
 
92722 
Moderate    Inter Info   
[1], [2], [3]
D0176
 
Betrixaban
 
C23H22ClN5O3
 
10275777 
Moderate    Inter Info   
[1], [2], [3]
D0210
 
Bromfenac
 
C15H12BrNO3
 
60726 
Moderate    Inter Info   
[1], [2], [3]
D0247
 
Cangrelor
 
C17H25Cl2F3N5O12P3S2
 
9854012 
Moderate    Inter Info   
[1], [2], [3]
D0250
 
Caplacizumab
 
NA
 
NA
Moderate    Inter Info   
[1], [2], [3]
D0336
 
Cilostazol
 
C20H27N5O2
 
2754 
Moderate    Inter Info   
[1], [2], [3]
D0364
 
Clopidogrel
 
C16H16ClNO2S
 
60606 
Moderate    Inter Info   
[1], [2], [3]
D0414
 
Dalteparin
 
C26H42N2O37S5
 
772 
Moderate    Inter Info   
[1], [2], [3]
D0415
 
Danaparoid
 
NA
 
NA
Moderate    Inter Info   
[1], [2], [3]
D0435
 
Defibrotide
 
C20H21N4O6P
 
135565962 
Moderate    Inter Info   
[1], [2], [3]
D0447
 
Desirudin
 
C287H440N80O110S6
 
16129703 
Moderate    Inter Info   
[1], [2], [3]
D0462
 
Dextran (-1)
 
C18H32O16
 
4125253 
Moderate    Inter Info   
[1], [2], [3]
D0463
 
Dextran (high molecular weight)
 
C18H32O16
 
4125253 
Moderate    Inter Info   
[1], [2], [3]
D0464
 
Dextran (low molecular weight)
 
C18H32O16
 
4125253 
Moderate    Inter Info   
[1], [2], [3]
D0476
 
Diclofenac
 
C14H11Cl2NO2
 
3033 
Moderate    Inter Info   
[1], [2], [3]
D0481
 
Dicoumarol
 
C19H12O6
 
54676038 
Moderate    Inter Info   
[1], [2], [3]
D0489
 
Diflunisal
 
C13H8F2O3
 
3059 
Moderate    Inter Info   
[1], [2], [3]
D0506
 
Dipyridamole
 
C24H40N8O4
 
3108 
Moderate    Inter Info   
[1], [2], [3]
D0551
 
Edoxaban
 
C24H30ClN7O4S
 
10280735 
Moderate    Inter Info   
[1], [2], [3]
D0574
 
Enoxaparin
 
C26H42N2O37S5
 
772 
Moderate    Inter Info   
[1], [2], [3]
D0586
 
Epoprostenol
 
C20H32O5
 
5282411 
Moderate    Inter Info   
[1], [2], [3]
D0624
 
Etodolac
 
C17H21NO3
 
3308 
Moderate    Inter Info   
[1], [2], [3]
D0638
 
Fedratinib
 
C27H36N6O3S
 
16722836 
Moderate    Inter Info   
[1], [2], [3]
D0645
 
Fenoprofen
 
C15H14O3
 
3342 
Moderate    Inter Info   
[1], [2], [3]
D0680
 
Flurbiprofen
 
C15H13FO2
 
3394 
Moderate    Inter Info   
[1], [2], [3]
D0690
 
Fondaparinux
 
C31H53N3O49S8
 
5282448 
Moderate    Inter Info   
[1], [2], [3]
D0753
 
Heparin
 
C26H42N2O37S5
 
772 
Moderate    Inter Info   
[1], [2], [3]
D0786
 
Ibuprofen
 
C13H18O2
 
3672 
Moderate    Inter Info   
[1], [2], [3]
D0792
 
Iloprost
 
C22H32O4
 
5311181 
Moderate    Inter Info   
[1], [2], [3]
D0800
 
Indomethacin
 
C19H16ClNO4
 
3715 
Moderate    Inter Info   
[1], [2], [3]
D0881
 
Ketoprofen
 
C16H14O3
 
3825 
Moderate    Inter Info   
[1], [2], [3]
D0882
 
Ketorolac
 
C15H13NO3
 
3826 
Moderate    Inter Info   
[1], [2], [3]
D0988
 
Meclofenamic acid
 
C14H11Cl2NO2
 
4037 
Moderate    Inter Info   
[1], [2], [3]
D0991
 
Mefenamic acid
 
C15H15NO2
 
4044 
Moderate    Inter Info   
[1], [2], [3]
D0995
 
Meloxicam
 
C14H13N3O4S2
 
54677470 
Moderate    Inter Info   
[1], [2], [3]
D1097
 
Nabumetone
 
C15H16O2
 
4409 
Moderate    Inter Info   
[1], [2], [3]
D1109
 
Naproxen
 
C14H14O3
 
156391 
Moderate    Inter Info   
[1], [2], [3]
D1196
 
Oxaprozin
 
C18H15NO3
 
4614 
Moderate    Inter Info   
[1], [2], [3]
D1251
 
Pentoxifylline
 
C13H18N4O3
 
4740 
Moderate    Inter Info   
[1], [2], [3]
D1274
 
Phenylbutazone
 
C19H20N2O2
 
4781 
Moderate    Inter Info   
[1], [2], [3]
D1300
 
Piroxicam
 
C15H13N3O4S
 
54676228 
Moderate    Inter Info   
[1], [2], [3]
D1328
 
Prasugrel
 
C20H20FNO3S
 
6918456 
Moderate    Inter Info   
[1], [2], [3]
D1417
 
Rivaroxaban
 
C19H18ClN3O5S
 
9875401 
Moderate    Inter Info   
[1], [2], [3]
D1518
 
Sulfinpyrazone
 
C23H20N2O3S
 
5342 
Moderate    Inter Info   
[1], [2], [3]
D1520
 
Sulindac
 
C20H17FO3S
 
1548887 
Moderate    Inter Info   
[1], [2], [3]
D1579
 
Ticagrelor
 
C23H28F2N6O4S
 
9871419 
Moderate    Inter Info   
[1], [2], [3]
D1581
 
Ticlopidine
 
C14H14ClNS
 
5472 
Moderate    Inter Info   
[1], [2], [3]
D1588
 
Tinzaparin
 
C26H42N2O37S5
 
772 
Moderate    Inter Info   
[1], [2], [3]
D1593
 
Tirofiban
 
C22H36N2O5S
 
60947 
Moderate    Inter Info   
[1], [2], [3]
D1606
 
Tolmetin
 
C15H15NO3
 
5509 
Moderate    Inter Info   
[1], [2], [3]
D1625
 
Treprostinil
 
C23H34O5
 
6918140 
Moderate    Inter Info   
[1], [2], [3]
D1705
 
Vorapaxar
 
C29H33FN2O4
 
10077130 
Moderate    Inter Info   
[1], [2], [3]
D1711
 
Warfarin
 
C19H16O4
 
54678486 
Moderate    Inter Info   
[1], [2], [3]
D0904
 
Lepirudin
 
C287H440N80O111S6
 
118856773 
Moderate    Inter Info   
[1], [2], [3]
D1395
 
Reteplase
 
NA
 
NA
Moderate    Inter Info   
[1], [2], [3]
D1506
 
Streptokinase
 
C11H19NO2
 
9815560 
Moderate    Inter Info   
[1], [2], [3]
D1550
 
Tenecteplase
 
NA
 
NA
Moderate    Inter Info   
[1], [2], [3]
D1669
 
Urokinase
 
NA
 
NA
Moderate    Inter Info   
[1], [2], [3]
References
1 Cerner Multum, Inc. "UK Summary of Product Characteristics.".
2 Li XL, Steiner M "Fish oil: a potent inhibitor of platelet adhesiveness." Blood 76 (1990): 938-45. [PMID: 2118400]
3 Product Information. Vascepa (icosapent). Amarin Pharmaceuticals Inc, Warren, NJ.