Details of Drug

Details of Drug

 Drug General Information (ID: D1802)
  Drug Name
Glucarpidase
  Drug Type Small molecule
  Drug Synonymous
Voraxaze (TN)
    Click to Show/Hide
  Therapeutic Class Antidotes
  Structure Could Not Find 2D Structure
3D Structure 2D Structure
  Formula Zn4+8
  InChI 1S/4Zn/q4*+2
  InChIKey LZQXMCNBQHANEY-UHFFFAOYSA-N
  Canonical SMILES [Zn+2].[Zn+2].[Zn+2].[Zn+2]
  External Link
Pubchem ID 21195079
TTD ID D0P4PZ

Drug-Drug Interaction Network
  Sunburst Graph
AM004  Affected intra/extra-hepatic metabolism
BM026  Increased metabolism (Unspecific)
  Relation Graph
 Full list of drugs interacting with Glucarpidase
      Affected intra/extra-hepatic metabolism
   Increased metabolism (Unspecific) Drug Num:  7
Drug ID
 
Drug Name
 Formula Pubchem ID Severity Level Interaction Detail REF
D1830
 
Leucovorin
 
C20H23N7O7
 
135403648 
Moderate    Inter Info   
[1]
D1241
 
Pemetrexed
 
C20H21N5O6
 
135410875 
Moderate    Inter Info   
[2], [1]
D1323
 
Pralatrexate
 
C23H23N7O5
 
148121 
Moderate    Inter Info   
[2], [1]
D1350
 
Proguanil
 
C11H16ClN5
 
6178111 
Moderate    Inter Info   
[2], [1]
D1366
 
Pyrimethamine
 
C12H13ClN4
 
4993 
Moderate    Inter Info   
[2], [1]
D1645
 
Trimethoprim
 
C14H18N4O3
 
5578 
Moderate    Inter Info   
[2], [1]
D1646
 
Trimetrexate
 
C19H23N5O3
 
5583 
Moderate    Inter Info   
[2], [1]
References
1 Product Information. Voraxaze (glucarpidase). BTG International Inc, West Conshohocken, PA.
2 Cerner Multum, Inc. "UK Summary of Product Characteristics.".