Details of Drug

Drug General Information (ID: D1774)
Drug Name	Difluprednate (ophthalmic)
Drug Type	Small molecule
Drug Synonymous	Durezol (TN) Click to Show/Hide
Disease Class	MC18: Ocular pain
Therapeutic Class	Topical Glucocorticoids
Structure
Structure	3D Structure		2D Structure
Formula	C27H34F2O7
InChI	1S/C27H34F2O7/c1-5-6-23(34)36-26(22(33)14-35-15(2)30)10-8-17-18-12-20(28)19-11-16(31)7-9-24(19,3)27(18,29)21(32)13-25(17,26)4/h7,9,11,17-18,20-21,32H,5-6,8,10,12-14H2,1-4H3/t17-,18-,20-,21-,24-,25-,26-,27-/m0/s1
InChIKey	WYQPLTPSGFELIB-JTQPXKBDSA-N
Canonical SMILES	CCCC(=O)OC1(CCC2C1(CC(C3(C2CC(C4=CC(=O)C=CC43C)F)F)O)C)C(=O)COC(=O)C
External Link
	Pubchem ID	443936
	CAS Number	CAS 23674-86-4
	CHEBI ID	CHEBI:31485
	TTD ID	D01ZOG
	INTEDE ID	DR0496

Drug-Drug Interaction Network
Sunburst Graph		Legend Information AM007 Pharmacodynamic antagonistic effects BM100 Antagonize the effect of vaccine/toxoid
Relation Graph

Full list of drugs interacting with Difluprednate (ophthalmic)
Pharmacodynamic antagonistic effects
	Antagonize the effect of vaccine/toxoid					Drug Num: 1
Drug ID		Drug Name	Formula	Pubchem ID	Severity Level		Interaction Detail	REF
D1890		Smallpox (Vaccinia) Vaccine, Live	NA	NA	Major		Inter Info	[1], [2], [3]

References
1	CDC. Centers for Disease Control and Prevention/ "Recommendations of the advisory committtee on immunization practices (ACIP): use of vaccines and immune globulins in persons with altered immunocompetence." MMWR Morb Mortal Wkly Rep 42(RR-04) (1993): 1-18. [PMID: 20300058]
2	Product Information. Dryvax (smallpox vaccine). Wyeth-Ayerst Laboratories, Philadelphia, PA.
3	CDC. Centers for Disease Control and Prevention "Clinical guidance for smallpox vaccine use in a postevent vaccination program.".