Details of Drug

Drug General Information (ID: D1766)
Drug Name	Coenzyme M
Drug Type	Small molecule
Drug Synonymous	2-Mercaptoethanesulfonic acid\|3375-50-6\|2-sulfanylethanesulfonic acid\|coenzyme M\|2-Mercaptoethanesulphonic acid\|HS-CoM\|reduced coenzyme M\|beta-Mercaptoethanesulfonic acid\|UNII-VHD28S0H7F\|2-mercaptoethanesulfonate\|Ethanesulfonic acid, 2-mercapto-\|2-sulfanylethylsulfonate\|2-Mercaptoethanesulfonic acid solution\|1-THIOETHANESULFONIC ACID\|VHD28S0H7F\|2-mercaptoethylsulfonate\|CoM\|CHEBI:17905\|Mistabronco\|NSC113891\|coenzima M\|reduced CoM\|2-sulfanylethane-1-sulfonic acid\|EINECS 222-167-0\|Spectrum_000153\|2-MERCAPTOETHANE\|2-mercaptoethylsulfonic acid\|SCHEMBL80705\|KBioSS_000633\|BIDD:GT0428\|DivK1c_000755\|2-mercapto-ethanesulfonic acid\|CHEMBL1098319\|DTXSID8023264\|KBio1_000755\|KBio2_000633\|KBio2_003201\|KBio2_005769\|2-mercapto-1-ethanesulfonic acid\|NINDS_000755\|ZINC3831040\|AKOS006227755\|DB09110\|IDI1_000755\|NCI60_000306\|DB-048487\|FT-0603636\|C03576\|375M506\|Q27102715\|3190F3F8-4A38-4A3A-85D6-6442B8D6C991\|2-Mercaptoethanesulfonic acid solution, for protein sequence analysis, ampule, 3.0 M+/-0.1 M in H2O (T) Click to Show/Hide
Therapeutic Class	Antidotes
Structure
Structure	3D Structure		2D Structure
Formula	C2H6O3S2
InChI	InChI=1S/C2H6O3S2/c3-7(4,5)2-1-6/h6H,1-2H2,(H,3,4,5)
InChIKey	ZNEWHQLOPFWXOF-UHFFFAOYSA-N
Canonical SMILES	C(CS(=O)(=O)O)S
External Link
External Link	Pubchem ID	598

Drug-Drug Interaction Network
Sunburst Graph		Legend Information AM006 Pharmacodynamic additive effects BM050 Increased risk of bleeding
Relation Graph

Full list of drugs interacting with Coenzyme M
Pharmacodynamic additive effects
	Increased risk of bleeding					Drug Num: 3
Drug ID		Drug Name	Formula	Pubchem ID	Severity Level		Interaction Detail	REF
D0087		Anisindione	C16H12O3	2197	Moderate		Inter Info	[1], [2], [3]
D0481		Dicoumarol	C19H12O6	54676038	Moderate		Inter Info	[1], [2], [3]
D1711		Warfarin	C19H16O4	54678486	Moderate		Inter Info	[1], [2], [3]

References
1	Bodiford AB, Kessler FO, Fermo JD, Ragucci KR "Elevated international normalized ratio with the consumption of grapefruit and use of warfarin." SAGE Open Med Case Rep 0 (2013): 1-3. [PMID: 27489634]
2	Guo LQ, Yamazoe Y "Inhibition of cytochrome P450 by furanocoumarins in grapefruit juice and herbal medicines." Acta Pharmacol Sin 25 (2004): 129-36. [PMID: 14769198]
3	Hall G, Lind MJ, Huang M, Moore A, Gane A, Roberts JT, Cantwell BM "Intravenous infusions of ifosfamide/mesna and perturbation of warfarin anticoagulant control." Postgrad Med J 66 (1990): 860-1. [PMID: 2129174]