Details of Drug

Drug General Information (ID: D1728)
Drug Name	Zolmitriptan
Drug Type	Small molecule
Drug Synonymous	AscoTop; Flezol; Zolmitriptane; Zolmitriptanum; Zomig; Zomigon; Zolmitriptan RapidFilm; Zolmitriptan [USAN]; Zomig Nasal Spray; Zomig ZMT; AscoTop (TN); BW-311C90; KS-5072; Zomig (TN); Zomig-ZMT; Zomigon (TN); Zomigoro (TN); Zomig, Zomigon, AscoTopand, Zomigoro, Zolmitriptan; (4S)-4-({3-[2-(dimethylamino)ethyl]-1H-indol-5-yl}methyl)-1,3-oxazolidin-2-one; (4S)-4-[[3-(2-dimethylaminoethyl)-1H-indol-5-yl]methyl]-1,3-oxazolidin-2-one; (S)-4-((3-(2-(Dimethylamino)ethyl)-1H-indol-5-yl)methyl)-2-oxazolidinone; (S)-4-((3-(2-(Dimethylamino)ethyl)indol-5-yl)methyl)-2-oxazolidinone; (S)-4-[3-(2-Dimethylamino-ethyl)-1H-indol-5-ylmethyl]-oxazolidin-2-one; (S)-4-[[3-[2-(dimethylamino)ethyl]-1H-indol-5-yl]methyl]-2-oxazolidinone; 4-((3-(2-(Dimethylamino)ethyl)-1H-indol-5-yl)methyl)-2-oxazolidinone; 4-[[3-(2-dimethylaminoethyl)-1H-indol-5-yl]methyl]oxazolidin-2-one Click to Show/Hide
Disease Class	8A80: Migraine
Therapeutic Class	Antimigraine Agents
Structure
Structure	3D Structure		2D Structure
Formula	C16H21N3O2
InChI	1S/C16H21N3O2/c1-19(2)6-5-12-9-17-15-4-3-11(8-14(12)15)7-13-10-21-16(20)18-13/h3-4,8-9,13,17H,5-7,10H2,1-2H3,(H,18,20)/t13-/m0/s1
InChIKey	ULSDMUVEXKOYBU-ZDUSSCGKSA-N
Canonical SMILES	CN(C)CCC1=CNC2=C1C=C(C=C2)CC3COC(=O)N3
External Link
	Pubchem ID	60857
	CAS Number	139264-17-8
	CHEBI ID	10124
	TTD ID	D0NG7O
	INTEDE ID	DR1733
	VARIDT ID	DR01278

Drug-Drug Interaction Network
Sunburst Graph		Legend Information AM004 Affected intra/extra-hepatic metabolism AM006 Pharmacodynamic additive effects BM017 CYP450 enzyme inhibition BM018 Non-CYP450 enzyme inhibition BM022 CYP450 enzyme induction BM038 Additive CNS depression effects BM041 Additive hypertensive effects BM046 Additive serotonergic effects BM049 Increased risk of atrioventricular block BM076 Increased risk of prolong QT interval BM109 Increased risk of other adverse reactions (Unspecific)
Relation Graph

Full list of drugs interacting with Zolmitriptan
Affected intra/extra-hepatic metabolism
	CYP450 enzyme inhibition					Drug Num: 16
Drug ID		Drug Name	Formula	Pubchem ID	Severity Level		Interaction Detail	REF
D0687		Fluvoxamine	C15H21F3N2O2	5324346	Moderate		Inter Info	[105], [123]
D0002		Abametapir (topical)	C12H12N2	15664	Moderate		Inter Info	[148]
D0251		Capmatinib	C23H17FN6O	25145656	Moderate		Inter Info	[105], [123]
D0337		Cimetidine	C10H16N6S	2756	Moderate		Inter Info	[83]
D0341		Ciprofloxacin	C17H18FN3O3	2764	Moderate		Inter Info	[105], [123]
D0432		Deferasirox	C21H15N3O4	214348	Moderate		Inter Info	[105], [123]
D0545		Echinacea	NA	NA	Moderate		Inter Info	[105], [123]
D0724		Givosiran	C78H139N11O30	119058042	Moderate		Inter Info	[105], [123]
D1054		Mexiletine	C11H17NO	4178	Moderate		Inter Info	[105], [123]
D1155		Norfloxacin	C16H18FN3O3	4539	Moderate		Inter Info	[105], [123]
D1160		Obeticholic acid	C26H44O4	447715	Moderate		Inter Info	[105], [123]
D1189		Osilodrostat	C13H10FN3	44139752	Moderate		Inter Info	[105], [123]
D1353		Propafenone	C21H27NO3	4932	Moderate		Inter Info	[105], [123]
D1432		Rucaparib	C19H18FN3O	9931954	Moderate		Inter Info	[105], [123]
D1571		Thiabendazole	C10H7N3S	5430	Moderate		Inter Info	[105], [123]
D1687		Vemurafenib	C23H18ClF2N3O3S	42611257	Moderate		Inter Info	[105], [123]
	Non-CYP450 enzyme inhibition					Drug Num: 5
Drug ID		Drug Name	Formula	Pubchem ID	Severity Level		Interaction Detail	REF
D0853		Isocarboxazid	C12H13N3O2	3759	Major		Inter Info	[11], [110], [111], [112], [22], [48], [53], [57], [113], [70], [73], [83], [94]
D1036		Methylene blue	C16H18ClN3S	6099	Major		Inter Info	[11], [110], [111], [112], [22], [48], [53], [57], [113], [70], [73], [83], [94]
D1263		Phenelzine	C8H12N2	3675	Major		Inter Info	[11], [110], [111], [112], [22], [48], [53], [57], [113], [70], [73], [83], [94]
D1345		Procarbazine	C12H19N3O	4915	Major		Inter Info	[11], [110], [111], [112], [22], [48], [53], [57], [113], [70], [73], [83], [94]
D1620		Tranylcypromine	C9H11N	19493	Major		Inter Info	[11], [110], [111], [112], [22], [48], [53], [57], [113], [70], [73], [83], [94]
	CYP450 enzyme induction					Drug Num: 2
Drug ID		Drug Name	Formula	Pubchem ID	Severity Level		Interaction Detail	REF
D1167		Olaparib	C24H23FN4O3	23725625	Moderate		Inter Info	[104], [105], [153]
D1556		Teriflunomide	C12H9F3N2O2	54684141	Moderate		Inter Info	[104], [105], [192]
Pharmacodynamic additive effects
	Additive CNS depression effects					Drug Num: 19
Drug ID		Drug Name	Formula	Pubchem ID	Severity Level		Interaction Detail	REF
D1089		Morphine	C17H19NO3	5288826	Moderate		Inter Info	[124], [125], [126], [127], [128], [48], [49], [17], [129], [130], [131], [35], [132], [31], [19], [5], [59], [133], [85], [134], [99], [135], [53], [136], [137], [11], [88], [138], [139], [140], [94], [87], [141], [142], [143], [144], [33], [145], [146], [147]
D1090		Morphine (liposomal)	C17H19NO3	5288826	Moderate		Inter Info	[124], [125], [126]
D0161		Benzhydrocodone	C25H25NO4	49836084	Moderate		Inter Info	[124], [125], [126]
D0219		Buprenorphine	C29H41NO4	644073	Moderate		Inter Info	[124], [125], [126], [127], [128], [48], [49], [17], [129], [130], [131], [35], [132], [31], [19], [5], [59], [133], [85], [134], [99], [135], [53], [136], [137], [11], [88], [138], [139], [140], [94], [87], [141], [142], [143], [144], [33], [145], [146], [147]
D0226		Butorphanol	C21H29NO2	5361092	Moderate		Inter Info	[124], [125], [126], [127], [128], [48], [49], [17], [129], [130], [131], [35], [132], [31], [19], [5], [59], [133], [85], [134], [99], [135], [53], [136], [137], [11], [88], [138], [139], [140], [94], [87], [141], [142], [143], [144], [33], [145], [146], [147]
D0379		Codeine	C18H21NO3	5284371	Moderate		Inter Info	[124], [125], [126], [127], [128], [48], [49], [17], [129], [130], [131], [35], [132], [31], [19], [5], [59], [133], [85], [134], [99], [135], [53], [136], [137], [11], [88], [138], [139], [140], [94], [87], [141], [142], [143], [144], [33], [145], [146], [147]
D0470		Dezocine	C16H23NO	3033053	Moderate		Inter Info	[124], [125], [126], [127], [128], [48], [49], [17], [129], [130], [131], [35], [132], [31], [19], [5], [59], [133], [85], [134], [99], [135], [53], [136], [137], [11], [88], [138], [139], [140], [94], [87], [141], [142], [143], [144], [33], [145], [146], [147]
D0493		Dihydrocodeine	C18H23NO3	5284543	Moderate		Inter Info	[124], [125], [126]
D0617		Ethanol	C2H6O	702	Moderate		Inter Info	[116], [26], [150], [105], [114]
D0772		Hydrocodone	C18H21NO3	5284569	Moderate		Inter Info	[124], [128], [133], [126], [88], [125], [49], [142], [17], [31], [143], [48], [59], [85], [135], [129], [33], [144], [53], [137], [132], [131], [19], [145], [99], [134], [138], [87], [146], [136], [147], [141], [127], [130], [35], [5], [11], [139], [140], [94]
D0776		Hydromorphone	C17H19NO3	5284570	Moderate		Inter Info	[124], [128], [133], [126], [88], [125], [49], [142], [17], [31], [143], [48], [59], [85], [135], [129], [33], [144], [53], [137], [132], [131], [19], [145], [99], [134], [138], [87], [146], [136], [147], [141], [127], [130], [35], [5], [11], [139], [140], [94]
D0909		Levacetylmethadol	C23H31NO2	15130	Moderate		Inter Info	[124], [125], [126]
D0923		Levorphanol	C17H23NO	5359272	Moderate		Inter Info	[124], [125], [126], [127], [128], [48], [49], [17], [129], [130], [131], [35], [132], [31], [19], [5], [59], [133], [85], [134], [99], [135], [53], [136], [137], [11], [88], [138], [139], [140], [94], [87], [141], [142], [143], [144], [33], [145], [146], [147]
D1017		Methadone	C21H27NO	4095	Moderate		Inter Info	[124], [128], [133], [126], [88], [125], [49], [142], [17], [31], [143], [48], [59], [85], [135], [129], [33], [144], [53], [137], [132], [131], [19], [145], [99], [134], [138], [87], [146], [136], [147], [141], [127], [130], [35], [5], [11], [139], [140], [94]
D1100		Nalbuphine	C21H27NO4	5311304	Moderate		Inter Info	[124], [125], [126], [127], [128], [48], [49], [17], [129], [130], [131], [35], [132], [31], [19], [5], [59], [133], [85], [134], [99], [135], [53], [136], [137], [11], [88], [138], [139], [140], [94], [87], [141], [142], [143], [144], [33], [145], [146], [147]
D1169		Oliceridine	C22H30N2O2S	66553195	Moderate		Inter Info	[124], [125], [126], [127], [128], [48], [49], [17], [129], [130], [131], [35], [132], [31], [19], [5], [59], [133], [85], [134], [99], [135], [53], [136], [137], [11], [88], [138], [139], [140], [94], [87], [141], [142], [143], [144], [33], [145], [146], [147]
D1203		Oxycodone	C18H21NO4	5284603	Moderate		Inter Info	[124], [125], [126], [127], [128], [48], [49], [17], [129], [130], [131], [35], [132], [31], [19], [5], [59], [133], [85], [134], [99], [135], [53], [136], [137], [11], [88], [138], [139], [140], [94], [87], [141], [142], [143], [144], [33], [145], [146], [147]
D1208		Oxymorphone	C17H19NO4	5284604	Moderate		Inter Info	[124], [125], [126], [127], [128], [48], [49], [17], [129], [130], [131], [35], [132], [31], [19], [5], [59], [133], [85], [134], [99], [135], [53], [136], [137], [11], [88], [138], [139], [140], [94], [87], [141], [142], [143], [144], [33], [145], [146], [147]
D1596		Tizanidine	C9H8ClN5S	5487	Moderate		Inter Info	[193]
	Additive hypertensive effects					Drug Num: 1
Drug ID		Drug Name	Formula	Pubchem ID	Severity Level		Interaction Detail	REF
D0538		Droxidopa	C9H11NO5	92974	Moderate		Inter Info	[149]
	Additive serotonergic effects					Drug Num: 33
Drug ID		Drug Name	Formula	Pubchem ID	Severity Level		Interaction Detail	REF
D0345		Citalopram	C20H21FN2O	2771	Major		Inter Info	[4], [5], [6], [7], [8], [9], [10], [11], [12], [13], [14], [15], [16], [17], [18], [19], [20], [21], [22], [23], [24], [25], [26], [27], [28], [29], [30], [31], [32], [33], [34], [35], [36], [37], [38], [39], [40], [41], [42], [43], [44], [45], [46], [47], [48], [49], [50], [51], [52], [53], [54], [55], [56], [57], [58], [59], [60], [61], [62], [63], [64], [65], [66], [67], [68], [69], [70], [71], [72], [73], [74], [75], [76], [77], [78], [79], [80], [81], [82], [83], [84], [85], [86], [87], [88], [89], [90], [91], [92], [93], [94], [95], [96], [97], [98], [99], [100], [101], [102]
D1616		Tramadol	C16H25NO2	33741	Major		Inter Info	[4], [5], [6], [7], [8], [9], [10], [11], [12], [13], [14], [15], [16], [17], [18], [19], [20], [21], [22], [23], [24], [25], [26], [27], [28], [29], [30], [31], [32], [33], [34], [35], [36], [37], [38], [39], [40], [41], [42], [43], [44], [45], [46], [47], [48], [49], [50], [51], [52], [53], [54], [55], [56], [57], [58], [59], [60], [61], [62], [63], [64], [65], [66], [67], [68], [69], [70], [71], [72], [73], [74], [75], [76], [77], [78], [79], [80], [81], [82], [83], [84], [85], [86], [87], [88], [89], [90], [91], [92], [93], [94], [95], [96], [97], [98], [99], [100], [101], [102]
D1689		Venlafaxine	C17H27NO2	5656	Major		Inter Info	[4], [5], [6], [7], [8], [9], [10], [11], [12], [13], [14], [15], [16], [17], [18], [19], [20], [21], [22], [23], [24], [25], [26], [27], [28], [29], [30], [31], [32], [33], [34], [35], [36], [37], [38], [39], [40], [41], [42], [43], [44], [45], [46], [47], [48], [49], [50], [51], [52], [53], [54], [55], [56], [57], [58], [59], [60], [61], [62], [63], [64], [65], [66], [67], [68], [69], [70], [71], [72], [73], [74], [75], [76], [77], [78], [79], [80], [81], [82], [83], [84], [85], [86], [87], [88], [89], [90], [91], [92], [93], [94], [95], [96], [97], [98], [99], [100], [101], [102]
D0446		Desipramine	C18H22N2	2995	Major		Inter Info	[4], [5], [6], [7], [8], [9], [10], [11], [12], [13], [14], [15], [16], [17], [18], [19], [20], [21], [22], [23], [24], [25], [26], [27], [28], [29], [30], [31], [32], [33], [34], [35], [36], [37], [38], [39], [40], [41], [42], [43], [44], [45], [46], [47], [48], [49], [50], [51], [52], [53], [54], [55], [56], [57], [58], [59], [60], [61], [62], [63], [64], [65], [66], [67], [68], [69], [70], [71], [72], [73], [74], [75], [76], [77], [78], [79], [80], [81], [82], [83], [84], [85], [86], [87], [88], [89], [90], [91], [92], [93], [94], [95], [96], [97], [98], [99], [100], [101], [102]
D0451		Desvenlafaxine	C16H25NO2	125017	Major		Inter Info	[4], [5], [6], [7], [8], [9], [10], [11], [12], [13], [14], [15], [16], [17], [18], [19], [20], [21], [22], [23], [24], [25], [26], [27], [28], [29], [30], [31], [32], [33], [34], [35], [36], [37], [38], [39], [40], [41], [42], [43], [44], [45], [46], [47], [48], [49], [50], [51], [52], [53], [54], [55], [56], [57], [58], [59], [60], [61], [62], [63], [64], [65], [66], [67], [68], [69], [70], [71], [72], [73], [74], [75], [76], [77], [78], [79], [80], [81], [82], [83], [84], [85], [86], [87], [88], [89], [90], [91], [92], [93], [94], [95], [96], [97], [98], [99], [100], [101], [102]
D0457		Dexfenfluramine	C12H16F3N	66265	Major		Inter Info	[4], [5], [6], [7], [8], [9], [10], [11], [12], [13], [14], [15], [16], [17], [18], [19], [20], [21], [22], [23], [24], [25], [26], [27], [28], [29], [30], [31], [32], [33], [34], [35], [36], [37], [38], [39], [40], [41], [42], [43], [44], [45], [46], [47], [48], [49], [50], [51], [52], [53], [54], [55], [56], [57], [58], [59], [60], [61], [62], [63], [64], [65], [66], [67], [68], [69], [70], [71], [72], [73], [74], [75], [76], [77], [78], [79], [80], [81], [82], [83], [84], [85], [86], [87], [88], [89], [90], [91], [92], [93], [94], [95], [96], [97], [98], [99], [100], [101], [102]
D0514		Dolasetron	C19H20N2O3	3033818	Major		Inter Info	[103], [104], [105], [106], [107], [108], [109]
D0539		Duloxetine	C18H19NOS	60835	Major		Inter Info	[4], [5], [6], [7], [8], [9], [10], [11], [12], [13], [14], [15], [16], [17], [18], [19], [20], [21], [22], [23], [24], [25], [26], [27], [28], [29], [30], [31], [32], [33], [34], [35], [36], [37], [38], [39], [40], [41], [42], [43], [44], [45], [46], [47], [48], [49], [50], [51], [52], [53], [54], [55], [56], [57], [58], [59], [60], [61], [62], [63], [64], [65], [66], [67], [68], [69], [70], [71], [72], [73], [74], [75], [76], [77], [78], [79], [80], [81], [82], [83], [84], [85], [86], [87], [88], [89], [90], [91], [92], [93], [94], [95], [96], [97], [98], [99], [100], [101], [102]
D0599		Escitalopram	C20H21FN2O	146570	Major		Inter Info	[4], [5], [6], [7], [8], [9], [10], [11], [12], [13], [14], [15], [16], [17], [18], [19], [20], [21], [22], [23], [24], [25], [26], [27], [28], [29], [30], [31], [32], [33], [34], [35], [36], [37], [38], [39], [40], [41], [42], [43], [44], [45], [46], [47], [48], [49], [50], [51], [52], [53], [54], [55], [56], [57], [58], [59], [60], [61], [62], [63], [64], [65], [66], [67], [68], [69], [70], [71], [72], [73], [74], [75], [76], [77], [78], [79], [80], [81], [82], [83], [84], [85], [86], [87], [88], [89], [90], [91], [92], [93], [94], [95], [96], [97], [98], [99], [100], [101], [102]
D0641		Fenfluramine	C12H16F3N	3337	Major		Inter Info	[4], [5], [6], [7], [8], [9], [10], [11], [12], [13], [14], [15], [16], [17], [18], [19], [20], [21], [22], [23], [24], [25], [26], [27], [28], [29], [30], [31], [32], [33], [34], [35], [36], [37], [38], [39], [40], [41], [42], [43], [44], [45], [46], [47], [48], [49], [50], [51], [52], [53], [54], [55], [56], [57], [58], [59], [60], [61], [62], [63], [64], [65], [66], [67], [68], [69], [70], [71], [72], [73], [74], [75], [76], [77], [78], [79], [80], [81], [82], [83], [84], [85], [86], [87], [88], [89], [90], [91], [92], [93], [94], [95], [96], [97], [98], [99], [100], [101], [102]
D0646		Fentanyl	C22H28N2O	3345	Major		Inter Info	[4], [5], [6], [7], [8], [9], [10], [11], [12], [13], [14], [15], [16], [17], [18], [19], [20], [21], [22], [23], [24], [25], [26], [27], [28], [29], [30], [31], [32], [33], [34], [35], [36], [37], [38], [39], [40], [41], [42], [43], [44], [45], [46], [47], [48], [49], [50], [51], [52], [53], [54], [55], [56], [57], [58], [59], [60], [61], [62], [63], [64], [65], [66], [67], [68], [69], [70], [71], [72], [73], [74], [75], [76], [77], [78], [79], [80], [81], [82], [83], [84], [85], [86], [87], [88], [89], [90], [91], [92], [93], [94], [95], [96], [97], [98], [99], [100], [101], [102]
D0676		Fluoxetine	C17H18F3NO	3386	Major		Inter Info	[4], [5], [6], [7], [8], [9], [10], [11], [12], [13], [14], [15], [16], [17], [18], [19], [20], [21], [22], [23], [24], [25], [26], [27], [28], [29], [30], [31], [32], [33], [34], [35], [36], [37], [38], [39], [40], [41], [42], [43], [44], [45], [46], [47], [48], [49], [50], [51], [52], [53], [54], [55], [56], [57], [58], [59], [60], [61], [62], [63], [64], [65], [66], [67], [68], [69], [70], [71], [72], [73], [74], [75], [76], [77], [78], [79], [80], [81], [82], [83], [84], [85], [86], [87], [88], [89], [90], [91], [92], [93], [94], [95], [96], [97], [98], [99], [100], [101], [102]
D0738		Granisetron	C18H24N4O	5284566	Major		Inter Info	[103], [104], [105], [106], [107], [108], [109]
D0897		Lasmiditan	C19H18F3N3O2	11610526	Major		Inter Info	[114], [115], [116]
D0920		Levomilnacipran	C15H22N2O	6917779	Major		Inter Info	[4], [5], [6], [7], [8], [9], [10], [11], [12], [13], [14], [15], [16], [17], [18], [19], [20], [21], [22], [23], [24], [25], [26], [27], [28], [29], [30], [31], [32], [33], [34], [35], [36], [37], [38], [39], [40], [41], [42], [43], [44], [45], [46], [47], [48], [49], [50], [51], [52], [53], [54], [55], [56], [57], [58], [59], [60], [61], [62], [63], [64], [65], [66], [67], [68], [69], [70], [71], [72], [73], [74], [75], [76], [77], [78], [79], [80], [81], [82], [83], [84], [85], [86], [87], [88], [89], [90], [91], [92], [93], [94], [95], [96], [97], [98], [99], [100], [101], [102]
D0933		Linezolid	C16H20FN3O4	441401	Major		Inter Info	[7], [8], [10], [105], [117], [16], [25], [118], [29], [30], [38], [43], [119], [48], [53], [54], [55], [120], [57], [60], [84], [90], [93], [94], [95], [96], [98], [102], [121]
D0952		Lorcaserin	C11H14ClN	11658860	Major		Inter Info	[122]
D1066		Milnacipran	C15H22N2O	65833	Major		Inter Info	[4], [5], [6], [7], [8], [9], [10], [104], [11], [12], [13], [14], [15], [16], [17], [18], [19], [20], [21], [22], [23], [24], [25], [26], [27], [28], [29], [30], [31], [32], [34], [35], [36], [37], [38], [39], [40], [41], [42], [43], [45], [46], [47], [48], [49], [50], [51], [52], [53], [54], [55], [57], [58], [59], [60], [61], [62], [63], [64], [65], [66], [67], [68], [69], [70], [71], [72], [73], [74], [75], [76], [77], [78], [79], [80], [81], [82], [83], [84], [85], [86], [87], [88], [89], [90], [91], [92], [93], [94], [95], [96], [97], [98], [99], [100], [101], [102]
D1075		Mirtazapine	C17H19N3	4205	Major		Inter Info	[4], [5], [6], [7], [8], [9], [10], [11], [12], [13], [14], [15], [16], [17], [18], [19], [20], [21], [22], [23], [24], [25], [26], [27], [28], [29], [30], [31], [32], [33], [34], [35], [36], [37], [38], [39], [40], [41], [42], [43], [44], [45], [46], [47], [48], [49], [50], [51], [52], [53], [54], [55], [56], [57], [58], [59], [60], [61], [62], [63], [64], [65], [66], [67], [68], [69], [70], [71], [72], [73], [74], [75], [76], [77], [78], [79], [80], [81], [82], [83], [84], [85], [86], [87], [88], [89], [90], [91], [92], [93], [94], [95], [96], [97], [98], [99], [100], [101], [102]
D1117		Nefazodone	C25H32ClN5O2	4449	Major		Inter Info	[4], [5], [6], [7], [8], [9], [10], [11], [12], [13], [14], [15], [16], [17], [18], [19], [20], [21], [22], [23], [24], [25], [26], [27], [28], [29], [30], [31], [32], [33], [34], [35], [36], [37], [38], [39], [40], [41], [42], [43], [44], [45], [46], [47], [48], [49], [50], [51], [52], [53], [54], [55], [56], [57], [58], [59], [60], [61], [62], [63], [64], [65], [66], [67], [68], [69], [70], [71], [72], [73], [74], [75], [76], [77], [78], [79], [80], [81], [82], [83], [84], [85], [86], [87], [88], [89], [90], [91], [92], [93], [94], [95], [96], [97], [98], [99], [100], [101], [102]
D1181		Ondansetron	C18H19N3O	4595	Major		Inter Info	[103], [104], [105], [106], [107], [108], [109]
D1200		Oxitriptan	C11H12N2O3	439280	Major		Inter Info	[13], [61], [63]
D1216		Palonosetron	C19H24N2O	6337614	Major		Inter Info	[103], [104], [105], [106], [107], [108], [109]
D1229		Paroxetine	C19H20FNO3	43815	Major		Inter Info	[4], [5], [6], [7], [8], [9], [10], [11], [12], [13], [14], [15], [16], [17], [18], [19], [20], [21], [22], [23], [24], [25], [26], [27], [28], [29], [30], [31], [32], [33], [34], [35], [36], [37], [38], [39], [40], [41], [42], [43], [44], [45], [46], [47], [48], [49], [50], [51], [52], [53], [54], [55], [56], [57], [58], [59], [60], [61], [62], [63], [64], [65], [66], [67], [68], [69], [70], [71], [72], [73], [74], [75], [76], [77], [78], [79], [80], [81], [82], [83], [84], [85], [86], [87], [88], [89], [90], [91], [92], [93], [94], [95], [96], [97], [98], [99], [100], [101], [102]
D1461		Sertraline	C17H17Cl2N	68617	Major		Inter Info	[4], [5], [6], [7], [8], [9], [10], [11], [12], [13], [14], [15], [16], [17], [18], [19], [20], [21], [22], [23], [24], [25], [26], [27], [28], [29], [30], [31], [32], [33], [34], [35], [36], [37], [38], [39], [40], [41], [42], [43], [44], [45], [46], [47], [48], [49], [50], [51], [52], [53], [54], [55], [56], [57], [58], [59], [60], [61], [62], [63], [64], [65], [66], [67], [68], [69], [70], [71], [72], [73], [74], [75], [76], [77], [78], [79], [80], [81], [82], [83], [84], [85], [86], [87], [88], [89], [90], [91], [92], [93], [94], [95], [96], [97], [98], [99], [100], [101], [102]
D1464		Sibutramine	C17H26ClN	5210	Major		Inter Info	[11], [24], [26], [34], [48], [53], [57], [74], [94]
D1535		Tapentadol	C14H23NO	9838022	Major		Inter Info	[4], [5], [6], [7], [8], [9], [10], [11], [12], [13], [14], [15], [16], [17], [18], [19], [20], [21], [22], [23], [24], [25], [26], [27], [28], [29], [30], [31], [32], [33], [34], [35], [36], [37], [38], [39], [40], [41], [42], [43], [44], [45], [46], [47], [48], [49], [50], [51], [52], [53], [54], [55], [56], [57], [58], [59], [60], [61], [62], [63], [64], [65], [66], [67], [68], [69], [70], [71], [72], [73], [74], [75], [76], [77], [78], [79], [80], [81], [82], [83], [84], [85], [86], [87], [88], [89], [90], [91], [92], [93], [94], [95], [96], [97], [98], [99], [100], [101], [102]
D1624		Trazodone	C19H22ClN5O	5533	Major		Inter Info	[4], [5], [6], [7], [8], [9], [10], [11], [12], [13], [14], [15], [16], [17], [18], [19], [20], [21], [22], [23], [24], [25], [26], [27], [28], [29], [30], [31], [32], [33], [34], [35], [36], [37], [38], [39], [40], [41], [42], [43], [44], [45], [46], [47], [48], [49], [50], [51], [52], [53], [54], [55], [56], [57], [58], [59], [60], [61], [62], [63], [64], [65], [66], [67], [68], [69], [70], [71], [72], [73], [74], [75], [76], [77], [78], [79], [80], [81], [82], [83], [84], [85], [86], [87], [88], [89], [90], [91], [92], [93], [94], [95], [96], [97], [98], [99], [100], [101], [102]
D1696		Vilazodone	C26H27N5O2	6918314	Major		Inter Info	[4], [5], [6], [7], [8], [9], [10], [11], [12], [13], [14], [15], [16], [17], [18], [19], [20], [21], [22], [23], [24], [25], [26], [27], [28], [29], [30], [31], [32], [33], [34], [35], [36], [37], [38], [39], [40], [41], [42], [43], [44], [45], [46], [47], [48], [49], [50], [51], [52], [53], [54], [55], [56], [57], [58], [59], [60], [61], [62], [63], [64], [65], [66], [67], [68], [69], [70], [71], [72], [73], [74], [75], [76], [77], [78], [79], [80], [81], [82], [83], [84], [85], [86], [87], [88], [89], [90], [91], [92], [93], [94], [95], [96], [97], [98], [99], [100], [101], [102]
D1708		Vortioxetine	C18H22N2S	9966051	Major		Inter Info	[4], [5], [6], [7], [8], [9], [10], [11], [12], [13], [14], [15], [16], [17], [18], [19], [20], [21], [22], [23], [24], [25], [26], [27], [28], [29], [30], [31], [32], [33], [34], [35], [36], [37], [38], [39], [40], [41], [42], [43], [44], [45], [46], [47], [48], [49], [50], [51], [52], [53], [54], [55], [56], [57], [58], [59], [60], [61], [62], [63], [64], [65], [66], [67], [68], [69], [70], [71], [72], [73], [74], [75], [76], [77], [78], [79], [80], [81], [82], [83], [84], [85], [86], [87], [88], [89], [90], [91], [92], [93], [94], [95], [96], [97], [98], [99], [100], [101], [102]
D1211		Ozanimod	C23H24N4O3	52938427	Moderate		Inter Info	[154], [155], [156], [157], [158], [159], [160], [161], [11], [12], [13], [14], [162], [110], [111], [163], [164], [20], [112], [22], [137], [165], [166], [167], [168], [169], [170], [171], [172], [173], [48], [50], [52], [53], [57], [61], [113], [174], [175], [63], [64], [65], [66], [67], [68], [70], [71], [72], [176], [73], [77], [78], [79], [80], [81], [177], [82], [83], [178], [89], [179], [180], [181], [182], [183], [94], [184], [185], [186], [187], [188], [189]
D1455		Selegiline	C13H17N	26757	Moderate		Inter Info	[53], [83], [94]
D1502		St. John's Wort	NA	NA	Moderate		Inter Info	[190], [191]
	Increased risk of atrioventricular block					Drug Num: 1
Drug ID		Drug Name	Formula	Pubchem ID	Severity Level		Interaction Detail	REF
D0992		Mefloquine	C17H16F6N2O	4046	Moderate		Inter Info	[105], [151], [152]
	Increased risk of prolong QT interval					Drug Num: 1
Drug ID		Drug Name	Formula	Pubchem ID	Severity Level		Interaction Detail	REF
D0937		Lisdexamfetamine	C15H25N3O	11597698	Moderate		Inter Info	[105]
	Increased risk of other adverse reactions (Unspecific)					Drug Num: 13
Drug ID		Drug Name	Formula	Pubchem ID	Severity Level		Interaction Detail	REF
D0228		Cabergoline	C26H37N5O2	54746	Major		Inter Info	[1], [2], [3]
D0557		Eletriptan	C22H26N2O2S	77993	Major		Inter Info	[1], [2], [3]
D1043		Methysergide	C21H27N3O2	9681	Major		Inter Info	[1], [2], [3]
D0041		Almotriptan	C17H25N3O2S	123606	Major		Inter Info	[1], [2], [3]
D0212		Bromocriptine	C32H40BrN5O5	31101	Major		Inter Info	[1], [2], [3]
D0494		Dihydroergotamine	C33H37N5O5	10531	Major		Inter Info	[1], [2], [3]
D0592		Ergometrine	C19H23N3O2	443884	Major		Inter Info	[1], [2], [3]
D0593		Ergotamine	C33H35N5O5	8223	Major		Inter Info	[1], [2], [3]
D0702		Frovatriptan	C14H17N3O	77992	Major		Inter Info	[1], [2], [3]
D1037		Methylergometrine	C20H25N3O2	8226	Major		Inter Info	[1], [2], [3]
D1110		Naratriptan	C17H25N3O2S	4440	Major		Inter Info	[1], [2], [3]
D1419		Rizatriptan	C15H19N5	5078	Major		Inter Info	[1], [2], [3]
D1521		Sumatriptan	C14H21N3O2S	5358	Major		Inter Info	[1], [2], [3]

References
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2	Product Information. Parlodel (bromocriptine). Sandoz Pharmaceuticals Corporation, East Hanover, NJ.
3	Product Information. Maxalt (rizatriptan). Merck &amp Co, Inc, West Point, PA.
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63	Product Information. Brintellix (vortioxetine). Takeda Pharmaceuticals America, Lincolnshire, IL.
64	Product Information. Celexa (citalopram). Forest Pharmaceuticals, St. Louis, MO.
65	Product Information. Cymbalta (duloxetine). Lilly, Eli and Company, Indianapolis, IN.
66	Product Information. D.H.E. 45 (dihydroergotamine). Sandoz Pharmaceuticals Corporation, East Hanover, NJ.
67	Product Information. Effexor (venlafaxine). Wyeth-Ayerst Laboratories, Philadelphia, PA.
68	Product Information. Fetzima (levomilnacipran). Forest Pharmaceuticals, St. Louis, MO.
69	Product Information. Flexeril (cyclobenzaprine). Merck & Co, Inc, West Point, PA.
70	Product Information. Imitrex (sumatriptan). Glaxo Wellcome, Research Triangle Park, NC.
71	Product Information. Lexapro (escitalopram). Forest Pharmaceuticals, St. Louis, MO.
72	Product Information. Luvox (fluvoxamine). Solvay Pharmaceuticals Inc, Marietta, GA.
73	Product Information. Maxalt (rizatriptan). Merck & Co, Inc, West Point, PA.
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