Details of Drug

Drug General Information (ID: D1652)
Drug Name	Troglitazone
Drug Type	Small molecule
Drug Synonymous	Noscal; Prelay; Resulin; Rezulin; Romglizone; Romozin; Troglitazona; Troglitazonum; Parke Davis brand of troglitazone; CS 045; GR 92132X; CS-045; GR-92132X; Resulin (TN); Rezulin (TN); Romozin (TN); Warner-Lambert brand of troglitazone; Troglitazone [USAN:BAN:INN]; Troglitazone (JAN/USAN/INN); (+-)-all-rac-5-(p-((6-Hydroxy-2,5,7,8-tetramethyl-2-chromanyl)methoxy)benzyl)-2,4-thiazolidinedione; (+/-)-5-[4-[(6-hydroxy-2,5,7,8-tetramethylchroman-2-yl)methoxy]benzyl]-2,4-thiazolidinedione; 2,4-Thiazolidinedione, 5-[[4-[(3,4-dihydro-6-hydroxy-2,5,7,8-tetramethyl-2H-1-benzopyran-2-yl)methoxy]phenyl]methyl]-(9CI); 5-(4-((6-hydroxy-2,5,7,8-tetramethylchroman-2-yl-methoxy)benzyl)-2,4-thiazolidinedione); 5-(4-(6-Hydroxy-2,5,7,8-tetramethylchroman-2-ylmethoxy)benzyl)thiazolidine-2,4-dione; 5-[(4-{[(6-hydroxy-2,5,7,8-tetramethyl-3,4-dihydro-2H-chromen-2-yl)methyl]oxy}phenyl)methyl]-1,3-thiazolidine-2,4-dione; 5-[[4-[(3,4-Dihydro-6-hydroxy-2,5,7,8-tetramethyl-2H-1-benzopyran-2-yl)methoxy]phenyl]methyl]-2,4-thiazolidinedione; 5-[[4-[(6-hydroxy-2,5,7,8-tetramethyl-3,4-dihydrochromen-2-yl)methoxy]phenyl]methyl]-1,3-thiazolidine-2,4-dione; 5-{4-[(6-hydroxy-2,5,7,8-tetramethyl-3,4-dihydro-2H-chromen-2-yl)methoxy]benzyl}-1,3-thiazolidine-2,4-dione Click to Show/Hide
Disease Class	5A2Y: Acute diabete complication
Therapeutic Class	Antiinflammatory Agents
Structure
Structure	3D Structure		2D Structure
Formula	C24H27NO5S
InChI	1S/C24H27NO5S/c1-13-14(2)21-18(15(3)20(13)26)9-10-24(4,30-21)12-29-17-7-5-16(6-8-17)11-19-22(27)25-23(28)31-19/h5-8,19,26H,9-12H2,1-4H3,(H,25,27,28)
InChIKey	GXPHKUHSUJUWKP-UHFFFAOYSA-N
Canonical SMILES	CC1=C(C2=C(CCC(O2)(C)COC3=CC=C(C=C3)CC4C(=O)NC(=O)S4)C(=C1O)C)C
External Link
	Pubchem ID	5591
	CAS Number	97322-87-7
	CHEBI ID	9753
	TTD ID	D06XZW
	INTEDE ID	DR1651
	VARIDT ID	DR00549

Drug-Drug Interaction Network
Sunburst Graph		Legend Information AM003 Affected organization distribution AM004 Affected intra/extra-hepatic metabolism AM006 Pharmacodynamic additive effects AM007 Pharmacodynamic antagonistic effects BM013 Competitive binding of plasma proteins BM017 CYP450 enzyme inhibition BM022 CYP450 enzyme induction BM023 UGT induction BM024 Competitive inhibition of metabolic enzyme BM055 Increased risk of hepatotoxicity BM064 Increased risk of hypoglycemia BM086 Antagonize the effect of antidiabetic agents BM089 Antagonize the effect of antihypertensive agents
Relation Graph

Full list of drugs interacting with Troglitazone
Affected organization distribution
	Competitive binding of plasma proteins					Drug Num: 1
Drug ID		Drug Name	Formula	Pubchem ID	Severity Level		Interaction Detail	REF
D1711		Warfarin	C19H16O4	54678486	Moderate		Inter Info	[381]
Affected intra/extra-hepatic metabolism
	CYP450 enzyme inhibition					Drug Num: 7
Drug ID		Drug Name	Formula	Pubchem ID	Severity Level		Interaction Detail	REF
D0002		Abametapir (topical)	C12H12N2	15664	Moderate		Inter Info	[35]
D0386		Conivaptan	C32H26N4O2	151171	Moderate		Inter Info	[119]
D0432		Deferasirox	C21H15N3O4	214348	Moderate		Inter Info	[173], [174]
D0906		Letermovir	C29H28F4N4O4	45138674	Moderate		Inter Info	[256]
D1063		Mifepristone	C29H35NO2	55245	Moderate		Inter Info	[271], [272]
D1398		Ribociclib	C23H30N8O	44631912	Moderate		Inter Info	[318], [319], [320], [321], [322], [323], [324], [325], [326]
D1432		Rucaparib	C19H18FN3O	9931954	Moderate		Inter Info	[189]
	CYP450 enzyme induction					Drug Num: 237
Drug ID		Drug Name	Formula	Pubchem ID	Severity Level		Interaction Detail	REF
D0959		Lumateperone	C24H28FN3O	21302490	Major		Inter Info	[8]
D1383		Ranolazine	C24H33N3O4	56959	Major		Inter Info	[11]
D0402		Cyclosporine	C62H111N11O12	5284373	Moderate		Inter Info	[15], [16], [17], [18], [19], [20], [21]
D0006		Abemaciclib	C27H32F2N8	46220502	Moderate		Inter Info	[36]
D0008		Acalabrutinib	C26H23N7O2	71226662	Moderate		Inter Info	[37]
D0035		Alfentanil	C21H32N6O3	51263	Moderate		Inter Info	[38], [39], [40], [41]
D0044		Alpelisib	C19H22F3N5O2S	56649450	Moderate		Inter Info	[42]
D0045		Alprazolam	C17H13ClN4	2118	Moderate		Inter Info	[15], [16], [17], [18], [19], [20], [21]
D0066		Amiodarone	C25H29I2NO3	2157	Moderate		Inter Info	[15], [16], [17], [18], [19], [20], [21]
D0069		Amlodipine	C20H25ClN2O5	2162	Moderate		Inter Info	[15], [16], [17], [18], [19], [20], [21]
D0080		Amprenavir	C25H35N3O6S	65016	Moderate		Inter Info	[43], [44], [45]
D0096		Apixaban	C25H25N5O4	10182969	Moderate		Inter Info	[46]
D0099		Apremilast	C22H24N2O7S	11561674	Moderate		Inter Info	[47]
D0100		Aprepitant	C23H21F7N4O3	135413536	Moderate		Inter Info	[48], [49]
D0105		Aripiprazole	C23H27Cl2N3O2	60795	Moderate		Inter Info	[50]
D0106		Armodafinil	C15H15NO2S	9690109	Moderate		Inter Info	[51], [52]
D0108		Artemether	C16H26O5	68911	Moderate		Inter Info	[53], [54], [55]
D0116		Atazanavir	C38H52N6O7	148192	Moderate		Inter Info	[56], [57], [58], [4], [59], [60], [61], [62], [63], [64], [65], [66], [67], [43], [68], [44], [45]
D0120		Atorvastatin	C33H35FN2O5	60823	Moderate		Inter Info	[69], [70], [71], [72], [73]
D0128		Avanafil	C23H26ClN7O3	9869929	Moderate		Inter Info	[74]
D0129		Avapritinib	C26H27FN10	118023034	Moderate		Inter Info	[54], [75]
D0133		Axitinib	C22H18N4OS	6450551	Moderate		Inter Info	[76], [77]
D0161		Benzhydrocodone	C25H25NO4	49836084	Moderate		Inter Info	[79], [80], [81]
D0194		Bosentan	C27H29N5O6S	104865	Moderate		Inter Info	[82]
D0195		Bosutinib	C26H29Cl2N5O3	5328940	Moderate		Inter Info	[83]
D0204		Brigatinib	C29H39ClN7O2P	68165256	Moderate		Inter Info	[53], [54], [85]
D0212		Bromocriptine	C32H40BrN5O5	31101	Moderate		Inter Info	[15], [16], [17], [18], [19], [20], [21]
D0219		Buprenorphine	C29H41NO4	644073	Moderate		Inter Info	[86]
D0222		Buspirone	C21H31N5O2	2477	Moderate		Inter Info	[87], [88], [89]
D0226		Butorphanol	C21H29NO2	5361092	Moderate		Inter Info	[90], [79], [91], [53], [54], [92], [93], [94], [80], [95], [96], [97], [98], [99], [100], [101], [102], [103], [81]
D0227		Cabazitaxel	C45H57NO14	9854073	Moderate		Inter Info	[104]
D0230		Cabozantinib	C28H24FN3O5	25102847	Moderate		Inter Info	[105], [106]
D0251		Capmatinib	C23H17FN6O	25145656	Moderate		Inter Info	[108]
D0255		Carbamazepine	C15H12N2O	2554	Moderate		Inter Info	[15], [16], [17], [18], [19], [20], [21]
D0262		Cariprazine	C21H32Cl2N4O	11154555	Moderate		Inter Info	[54], [109]
D0300		Cenobamate	C10H10ClN5O2	11962412	Moderate		Inter Info	[110]
D0324		Chlorpromazine	C17H19ClN2S	2726	Moderate		Inter Info	[15], [16], [17], [18], [19], [20], [21]
D0356		Clobazam	C16H13ClN2O2	2789	Moderate		Inter Info	[15], [16], [17], [18], [19], [20], [21]
D0376		Cobimetinib	C21H21F3IN3O2	16222096	Moderate		Inter Info	[118]
D0379		Codeine	C18H21NO3	5284371	Moderate		Inter Info	[15], [16], [17], [18], [19], [20], [21]
D0387		Conjugated estrogens	C18H21NaO5S	45357473	Moderate		Inter Info	[120], [121], [122], [123], [124], [125], [126], [127], [128], [129], [130], [131], [132], [133], [134], [135], [136], [137], [138], [139], [140], [141], [142], [143], [144], [145], [146], [147], [148], [149], [150], [151], [152], [153], [154], [155], [156], [157], [158], [159], [160], [161], [162], [163], [164], [165], [166]
D0393		Crizotinib	C21H22Cl2FN5O	11626560	Moderate		Inter Info	[167], [54], [168]
D0400		Cyclophosphamide	C7H15Cl2N2O2P	2907	Moderate		Inter Info	[15], [16], [17], [18], [19], [20], [21]
D0406		Dabrafenib	C23H20F3N5O2S2	44462760	Moderate		Inter Info	[53], [54], [169]
D0419		Dapsone	C12H12N2O2S	2955	Moderate		Inter Info	[15], [16], [17], [18], [19], [20], [21]
D0424		Darifenacin	C28H30N2O2	444031	Moderate		Inter Info	[170]
D0425		Darolutamide	C19H19ClN6O2	67171867	Moderate		Inter Info	[171]
D0426		Darunavir	C27H37N3O7S	213039	Moderate		Inter Info	[56], [57], [58], [4], [59], [60], [61], [62], [63], [64], [65], [66], [67], [43], [68], [44], [45]
D0428		Dasatinib	C22H26ClN7O2S	3062316	Moderate		Inter Info	[53], [54], [172]
D0439		Delavirdine	C22H28N6O3S	5625	Moderate		Inter Info	[175], [176], [30]
D0450		Desogestrel	C22H30O	40973	Moderate		Inter Info	[177], [20], [178]
D0453		Dexamethasone	C22H29FO5	5743	Moderate		Inter Info	[15], [16], [17], [18], [19], [20], [21]
D0466		Dextromethorphan	C18H25NO	5360696	Moderate		Inter Info	[15], [16], [17], [18], [19], [20], [21]
D0473		Diazepam	C16H13ClN2O	3016	Moderate		Inter Info	[15], [16], [17], [18], [19], [20], [21]
D0494		Dihydroergotamine	C33H37N5O5	10531	Moderate		Inter Info	[53], [54], [179]
D0497		Diltiazem	C22H26N2O4S	39186	Moderate		Inter Info	[128], [180], [181], [182], [156]
D0511		Docetaxel	C43H53NO14	148124	Moderate		Inter Info	[183], [184], [185], [186], [187]
D0516		Donepezil	C24H29NO3	3152	Moderate		Inter Info	[15], [16], [17], [18], [19], [20], [21]
D0518		Doravirine	C17H11ClF3N5O3	58460047	Moderate		Inter Info	[188], [189]
D0528		Doxorubicin	C27H29NO11	31703	Moderate		Inter Info	[54], [190], [191], [192]
D0534		Dronedarone	C31H44N2O5S	208898	Moderate		Inter Info	[193]
D0536		Drospirenone	C24H30O3	68873	Moderate		Inter Info	[194], [177], [20], [178]
D0543		Duvelisib	C22H17ClN6O	50905713	Moderate		Inter Info	[195]
D0545		Echinacea	NA	NA	Moderate		Inter Info	[53], [196]
D0554		Efavirenz	C14H9ClF3NO2	64139	Moderate		Inter Info	[182]
D0555		Elagolix	C32H30F5N3O5	11250647	Moderate		Inter Info	[197]
D0559		Eliglustat	C23H36N2O4	23652731	Moderate		Inter Info	[198]
D0569		Encorafenib	C22H27ClFN7O4S	50922675	Moderate		Inter Info	[199]
D0577		Entrectinib	C31H34F2N6O2	25141092	Moderate		Inter Info	[54], [200]
D0578		Enzalutamide	C21H16F4N4O2S	15951529	Moderate		Inter Info	[201]
D0593		Ergotamine	C33H35N5O5	8223	Moderate		Inter Info	[53], [54], [179]
D0595		Erlotinib	C22H23N3O4	176870	Moderate		Inter Info	[202], [203]
D0597		Erythromycin	C37H67NO13	12560	Moderate		Inter Info	[15], [16], [17], [18], [19], [20], [21]
D0605		Esterified estrogens	NA	NA	Moderate		Inter Info	[120], [121], [122], [123], [124], [125], [126], [127], [128], [129], [130], [131], [132], [133], [134], [135], [136], [137], [138], [139], [140], [141], [142], [143], [144], [145], [146], [147], [148], [149], [150], [151], [152], [153], [154], [155], [156], [157], [158], [159], [160], [161], [162], [163], [164], [165], [166]
D0606		Estradiol	C18H24O2	5757	Moderate		Inter Info	[120], [121], [122], [123], [124], [125], [126], [127], [128], [129], [130], [131], [132], [133], [134], [135], [136], [137], [138], [139], [140], [141], [142], [143], [144], [145], [146], [147], [148], [149], [150], [151], [152], [153], [154], [155], [156], [157], [158], [159], [160], [161], [162], [163], [164], [165], [166]
D0607		Estradiol (topical)	C18H24O2	5757	Moderate		Inter Info	[124], [134], [159]
D0610		Estrone sulfate	C18H22O5S	3001028	Moderate		Inter Info	[124], [134], [159]
D0612		Eszopiclone	C17H17ClN6O3	969472	Moderate		Inter Info	[204]
D0619		Ethinylestradiol	C20H24O2	5991	Moderate		Inter Info	[177], [20], [178]
D0626		Etonogestrel	C22H28O2	6917715	Moderate		Inter Info	[194], [177], [20], [178]
D0628		Etravirine	C20H15BrN6O	193962	Moderate		Inter Info	[205]
D0629		Everolimus	C53H83NO14	6442177	Moderate		Inter Info	[53], [54], [206]
D0630		Exemestane	C20H24O2	60198	Moderate		Inter Info	[207]
D0638		Fedratinib	C27H36N6O3S	16722836	Moderate		Inter Info	[15], [16], [17], [18], [19], [20], [21]
D0640		Felodipine	C18H19Cl2NO4	3333	Moderate		Inter Info	[15], [16], [17], [18], [19], [20], [21]
D0646		Fentanyl	C22H28N2O	3345	Moderate		Inter Info	[90], [79], [91], [53], [54], [92], [93], [94], [80], [95], [96], [97], [98], [99], [100], [101], [102], [103], [81]
D0655		Fesoterodine	C26H37NO3	6918558	Moderate		Inter Info	[208]
D0665		Flibanserin	C20H21F3N4O	6918248	Moderate		Inter Info	[209]
D0692		Fosamprenavir	C25H36N3O9PS	131536	Moderate		Inter Info	[56], [57], [58], [4], [59], [60], [61], [62], [63], [64], [65], [66], [67], [43], [68], [44], [45]
D0693		Fosaprepitant	C23H22F7N4O6P	135413538	Moderate		Inter Info	[48], [49]
D0699		Fostamatinib	C23H26FN6O9P	11671467	Moderate		Inter Info	[212], [213], [30]
D0713		Gefitinib	C22H24ClFN4O3	123631	Moderate		Inter Info	[202], [214]
D0720		Gilteritinib	C29H44N8O3	49803313	Moderate		Inter Info	[215]
D0725		Glasdegib	C21H22N6O	25166913	Moderate		Inter Info	[219]
D0726		Glecaprevir	C38H46F4N6O9S	66828839	Moderate		Inter Info	[220]
D0738		Granisetron	C18H24N4O	5284566	Moderate		Inter Info	[15], [16], [17], [18], [19], [20], [21]
D0739		Grazoprevir	C38H50N6O9S	44603531	Moderate		Inter Info	[221]
D0745		Guanfacine	C9H9Cl2N3O	3519	Moderate		Inter Info	[54], [222], [223]
D0772		Hydrocodone	C18H21NO3	5284569	Moderate		Inter Info	[90], [79], [91], [53], [54], [92], [93], [94], [80], [95], [96], [97], [98], [99], [100], [101], [102], [103], [81]
D0773		Hydrocortisone	C21H30O5	5754	Moderate		Inter Info	[15], [16], [17], [18], [19], [20], [21]
D0785		Ibrutinib	C25H24N6O2	24821094	Moderate		Inter Info	[224]
D0790		Ifosfamide	C7H15Cl2N2O2P	3690	Moderate		Inter Info	[15], [16], [17], [18], [19], [20], [21]
D0793		Imatinib	C29H31N7O	5291	Moderate		Inter Info	[226], [4], [53], [54], [227], [228]
D0795		Imipramine	C19H24N2	3696	Moderate		Inter Info	[15], [16], [17], [18], [19], [20], [21]
D0799		Indinavir	C36H47N5O4	5362440	Moderate		Inter Info	[56], [57], [58], [4], [59], [60], [61], [62], [63], [64], [65], [66], [67], [43], [68], [44], [45]
D0845		Irinotecan	C33H38N4O6	60838	Moderate		Inter Info	[229], [230], [231], [232], [233], [234], [235], [236], [237], [238], [239], [240], [241], [242], [243]
D0846		Irinotecan (liposomal)	C33H38N4O6	60838	Moderate		Inter Info	[230], [231], [236]
D0852		Isavuconazonium	C35H35F2N8O5S+	6918606	Moderate		Inter Info	[244]
D0868		Ivabradine	C27H36N2O5	132999	Moderate		Inter Info	[54], [245]
D0869		Ivacaftor	C24H28N2O3	16220172	Moderate		Inter Info	[246], [247], [248], [249]
D0873		Ixabepilone	C27H42N2O5S	6445540	Moderate		Inter Info	[250]
D0874		Ixazomib	C14H19BCl2N2O4	25183872	Moderate		Inter Info	[251]
D0892		Lansoprazole	C16H14F3N3O2S	3883	Moderate		Inter Info	[15], [16], [17], [18], [19], [20], [21]
D0894		Lapatinib	C29H26ClFN4O4S	208908	Moderate		Inter Info	[53], [54], [252]
D0896		Larotrectinib	C21H22F2N6O2	46188928	Moderate		Inter Info	[53], [54], [253]
D0899		Lefamulin	C28H45NO5S	25185057	Moderate		Inter Info	[254]
D0901		Lemborexant	C22H20F2N4O2	56944144	Moderate		Inter Info	[53], [255]
D0911		Levamlodipine	C20H25ClN2O5	9822750	Moderate		Inter Info	[15], [16], [17], [18], [19], [20], [21]
D0922		Levonorgestrel	C21H28O2	13109	Moderate		Inter Info	[194], [177], [20], [178]
D0930		Linagliptin	C25H28N8O2	10096344	Moderate		Inter Info	[257]
D0946		Lonafarnib	C27H31Br2ClN4O2	148195	Moderate		Inter Info	[258]
D0950		Loratadine	C22H23ClN2O2	3957	Moderate		Inter Info	[15], [16], [17], [18], [19], [20], [21]
D0953		Lorlatinib	C21H19FN6O2	71731823	Moderate		Inter Info	[259]
D0954		Losartan	C22H23ClN6O	3961	Moderate		Inter Info	[15], [16], [17], [18], [19], [20], [21]
D0956		Lovastatin	C24H36O5	53232	Moderate		Inter Info	[15], [16], [17], [18], [19], [20], [21]
D0962		Lurbinectedin	C41H44N4O10S	57327016	Moderate		Inter Info	[260]
D0965		Macimorelin	C26H30N6O3	9804938	Moderate		Inter Info	[261]
D0966		Macitentan	C19H20Br2N6O4S	16004692	Moderate		Inter Info	[262], [263]
D0980		Maraviroc	C29H41F2N5O	3002977	Moderate		Inter Info	[53], [264]
D0990		Medroxyprogesterone acetate	C24H34O4	6279	Moderate		Inter Info	[265], [266], [166]
D0992		Mefloquine	C17H16F6N2O	4046	Moderate		Inter Info	[267]
D0993		Megestrol acetate	C24H32O4	11683	Moderate		Inter Info	[124], [134], [159]
D1011		Mestranol	C21H26O2	6291	Moderate		Inter Info	[177], [20], [178]
D1017		Methadone	C21H27NO	4095	Moderate		Inter Info	[90], [79], [91], [53], [54], [92], [93], [94], [80], [95], [96], [97], [98], [99], [100], [101], [102], [103], [81]
D1037		Methylergometrine	C20H25N3O2	8226	Moderate		Inter Info	[53], [54], [179]
D1043		Methysergide	C21H27N3O2	9681	Moderate		Inter Info	[53], [54], [179]
D1060		Midazolam	C18H13ClFN3	4192	Moderate		Inter Info	[15], [16], [17], [18], [19], [20], [21]
D1062		Midostaurin	C35H30N4O4	9829523	Moderate		Inter Info	[269], [270]
D1075		Mirtazapine	C17H19N3	4205	Moderate		Inter Info	[273], [274], [275], [276]
D1081		Modafinil	C15H15NO2S	4236	Moderate		Inter Info	[51], [52]
D1087		Montelukast	C35H36ClNO3S	5281040	Moderate		Inter Info	[277]
D1101		Naldemedine	C32H34N4O6	54732242	Moderate		Inter Info	[15], [16], [17], [18], [19], [20], [21]
D1104		Naloxegol	C34H53NO11	56959087	Moderate		Inter Info	[278]
D1117		Nefazodone	C25H32ClN5O2	4449	Moderate		Inter Info	[15], [16], [17], [18], [19], [20], [21]
D1119		Nelfinavir	C32H45N3O4S	64143	Moderate		Inter Info	[56], [57], [58], [4], [59], [60], [61], [62], [63], [64], [65], [66], [67], [43], [68], [44], [45]
D1128		Nevirapine	C15H14N4O	4463	Moderate		Inter Info	[15], [16], [17], [18], [19], [20], [21]
D1130		Nicardipine	C26H29N3O6	4474	Moderate		Inter Info	[15], [16], [17], [18], [19], [20], [21]
D1134		Nifedipine	C17H18N2O6	4485	Moderate		Inter Info	[15], [16], [17], [18], [19], [20], [21]
D1136		Nilotinib	C28H22F3N7O	644241	Moderate		Inter Info	[280]
D1143		Nitisinone	C14H10F3NO5	115355	Moderate		Inter Info	[15], [16], [17], [18], [19], [20], [21]
D1154		Norethisterone	C20H26O2	6230	Moderate		Inter Info	[177], [20], [178]
D1157		Norgestrel	C21H28O2	13109	Moderate		Inter Info	[177], [20], [178]
D1167		Olaparib	C24H23FN4O3	23725625	Moderate		Inter Info	[53], [54], [281]
D1169		Oliceridine	C22H30N2O2S	66553195	Moderate		Inter Info	[79], [80], [81]
D1189		Osilodrostat	C13H10FN3	44139752	Moderate		Inter Info	[212], [282], [30]
D1190		Osimertinib	C28H33N7O2	71496458	Moderate		Inter Info	[283]
D1198		Oxcarbazepine	C15H12N2O2	34312	Moderate		Inter Info	[284], [285], [286]
D1203		Oxycodone	C18H21NO4	5284603	Moderate		Inter Info	[90], [79], [91], [53], [54], [92], [93], [94], [80], [95], [96], [97], [98], [99], [100], [101], [102], [103], [81]
D1212		Paclitaxel	C47H51NO14	36314	Moderate		Inter Info	[287], [288], [289], [290]
D1214		Palbociclib	C24H29N7O2	5330286	Moderate		Inter Info	[53], [54], [291]
D1221		Panobinostat	C21H23N3O2	6918837	Moderate		Inter Info	[292]
D1232		Pazopanib	C21H23N7O2S	10113978	Moderate		Inter Info	[293]
D1242		Pemigatinib	C24H27F2N5O4	86705695	Moderate		Inter Info	[294]
D1290		Pimavanserin	C25H34FN3O2	10071196	Moderate		Inter Info	[298]
D1292		Pimozide	C28H29F2N3O	16362	Moderate		Inter Info	[15], [16], [17], [18], [19], [20], [21]
D1294		Pioglitazone	C19H20N2O3S	4829	Moderate		Inter Info	[299]
D1313		Ponatinib	C29H27F3N6O	24826799	Moderate		Inter Info	[53], [54], [300]
D1330		Praziquantel	C19H24N2O2	4891	Moderate		Inter Info	[301], [53], [302], [303]
D1348		Progesterone	C21H30O2	5994	Moderate		Inter Info	[120], [121], [122], [123], [124], [125], [126], [127], [128], [129], [130], [131], [132], [133], [134], [135], [136], [137], [138], [139], [140], [141], [142], [143], [144], [145], [146], [147], [148], [149], [150], [151], [152], [153], [154], [155], [156], [157], [158], [159], [160], [161], [162], [163], [164], [165], [166]
D1349		Progesterone (topical)	C21H30O2	5994	Moderate		Inter Info	[124], [134], [159]
D1368		Quetiapine	C21H25N3O2S	5002	Moderate		Inter Info	[53], [304], [305], [306], [307]
D1371		Quinidine	C20H24N2O2	441074	Moderate		Inter Info	[15], [16], [17], [18], [19], [20], [21]
D1372		Quinine	C20H24N2O2	3034034	Moderate		Inter Info	[308], [309], [310], [311], [312], [313]
D1378		Ramelteon	C16H21NO2	208902	Moderate		Inter Info	[314]
D1401		Rifapentine	C47H64N4O12	135403821	Moderate		Inter Info	[327], [328]
D1404		Rilpivirine	C22H18N6	6451164	Moderate		Inter Info	[53], [167], [54], [329]
D1408		Riociguat	C20H19FN8O2	11304743	Moderate		Inter Info	[330]
D1409		Ripretinib	C24H21BrFN5O2	71584930	Moderate		Inter Info	[53], [331]
D1415		Ritonavir	C37H48N6O5S2	392622	Moderate		Inter Info	[56], [57], [58], [4], [59], [60], [61], [62], [63], [64], [65], [66], [67], [43], [68], [44], [45]
D1417		Rivaroxaban	C19H18ClN3O5S	9875401	Moderate		Inter Info	[332]
D1423		Rolapitant	C25H26F6N2O2	10311306	Moderate		Inter Info	[333]
D1434		Ruxolitinib	C17H18N6	25126798	Moderate		Inter Info	[334]
D1444		Saquinavir	C38H50N6O5	441243	Moderate		Inter Info	[56], [57], [58], [4], [59], [60], [61], [62], [63], [64], [65], [66], [67], [43], [68], [44], [45]
D1449		Saxagliptin	C18H25N3O2	11243969	Moderate		Inter Info	[335]
D1459		Selpercatinib	C29H31N7O3	134436906	Moderate		Inter Info	[212], [336]
D1460		Selumetinib	C17H15BrClFN4O3	10127622	Moderate		Inter Info	[337]
D1461		Sertraline	C17H17Cl2N	68617	Moderate		Inter Info	[15], [16], [17], [18], [19], [20], [21]
D1465		Sildenafil	C22H30N6O4S	135398744	Moderate		Inter Info	[338], [339], [340], [341]
D1466		Silodosin	C25H32F3N3O4	5312125	Moderate		Inter Info	[53], [54], [342]
D1473		Simvastatin	C25H38O5	54454	Moderate		Inter Info	[15], [16], [17], [18], [19], [20], [21]
D1476		Sirolimus	C51H79NO13	5284616	Moderate		Inter Info	[53], [54], [343], [344]
D1491		Solifenacin	C23H26N2O2	154059	Moderate		Inter Info	[345]
D1496		Sonidegib	C26H26F3N3O3	24775005	Moderate		Inter Info	[346]
D1497		Sorafenib	C21H16ClF3N4O3	216239	Moderate		Inter Info	[347]
D1505		Stiripentol	C14H18O3	5311454	Moderate		Inter Info	[54], [227], [348]
D1522		Sunitinib	C22H27FN4O2	5329102	Moderate		Inter Info	[53], [54], [349]
D1526		Tacrolimus	C44H69NO12	445643	Moderate		Inter Info	[53], [54], [343], [344]
D1533		Tamoxifen	C26H29NO	2733526	Moderate		Inter Info	[350], [351], [352], [353]
D1536		Tasimelteon	C15H19NO2	10220503	Moderate		Inter Info	[354]
D1538		Tazemetostat	C34H44N4O4	66558664	Moderate		Inter Info	[355]
D1544		Telithromycin	C43H65N5O10	3002190	Moderate		Inter Info	[212], [356], [357]
D1546		Telotristat ethyl	C27H26ClF3N6O3	25181577	Moderate		Inter Info	[54], [358]
D1549		Temsirolimus	C56H87NO16	6918289	Moderate		Inter Info	[53], [54], [359]
D1558		Testosterone	C19H28O2	6013	Moderate		Inter Info	[15], [16], [17], [18], [19], [20], [21]
D1579		Ticagrelor	C23H28F2N6O4S	9871419	Moderate		Inter Info	[4], [54], [360], [361], [362]
D1600		Tofacitinib	C16H20N6O	9926791	Moderate		Inter Info	[53], [365]
D1608		Tolvaptan	C26H25ClN2O3	216237	Moderate		Inter Info	[54], [366]
D1612		Toremifene	C26H28ClNO	3005573	Moderate		Inter Info	[367], [53], [54], [351], [368]
D1632		Triazolam	C17H12Cl2N4	5556	Moderate		Inter Info	[15], [16], [17], [18], [19], [20], [21]
D1660		Tucatinib	C26H24N8O2	51039094	Moderate		Inter Info	[212], [370], [30]
D1663		Ubrogepant	C29H26F3N5O3	68748835	Moderate		Inter Info	[374]
D1664		Ulipristal	C28H35NO3	13559281	Moderate		Inter Info	[54], [375]
D1687		Vemurafenib	C23H18ClF2N3O3S	42611257	Moderate		Inter Info	[376]
D1688		Venetoclax	C45H50ClN7O7S	49846579	Moderate		Inter Info	[377]
D1689		Venlafaxine	C17H27NO2	5656	Moderate		Inter Info	[15], [16], [17], [18], [19], [20], [21]
D1690		Verapamil	C27H38N2O4	2520	Moderate		Inter Info	[15], [16], [17], [18], [19], [20], [21]
D1696		Vilazodone	C26H27N5O2	6918314	Moderate		Inter Info	[378]
D1697		Vinblastine	C46H58N4O9	13342	Moderate		Inter Info	[15], [16], [17], [18], [19], [20], [21]
D1698		Vincristine	C46H56N4O10	5978	Moderate		Inter Info	[15], [16], [17], [18], [19], [20], [21]
D1699		Vincristine (liposome)	C46H56N4O10	5978	Moderate		Inter Info	[17], [19], [20]
D1706		Voriconazole	C16H14F3N5O	71616	Moderate		Inter Info	[379]
D1708		Vortioxetine	C18H22N2S	9966051	Moderate		Inter Info	[380]
D1713		Yohimbine	C21H26N2O3	8969	Moderate		Inter Info	[17], [19], [20]
D1718		Zanubrutinib	C27H29N5O3	135565884	Moderate		Inter Info	[382]
D1721		Zileuton	C11H12N2O2S	60490	Moderate		Inter Info	[15], [16], [17], [18], [19], [20], [21]
D1729		Zolpidem	C19H21N3O	5732	Moderate		Inter Info	[54], [383], [384], [385]
D1730		Zonisamide	C8H8N2O3S	5734	Moderate		Inter Info	[386], [387]
D0308		Cevimeline	C10H17NOS	83898	Minor		Inter Info	[388]
D0178		Bexarotene	C24H28O2	82146	Minor		Inter Info	[353]
D0420		Dapsone (topical)	C12H12N2O2S	2955	Minor		Inter Info	[394], [246], [249]
D0513		Dofetilide	C19H27N3O5S2	71329	Minor		Inter Info	[395]
D0515		Dolutegravir	C20H19F2N3O5	54726191	Minor		Inter Info	[396]
D0700		Fostemsavir	C25H26N7O8P	11319217	Minor		Inter Info	[212], [397], [30]
D0927		Lidocaine	C14H22N2O	3676	Minor		Inter Info	[401], [402], [403], [404]
D1074		Mirabegron	C21H24N4O2S	9865528	Minor		Inter Info	[405]
D1716		Zaleplon	C17H15N5O	5719	Minor		Inter Info	[407]
D1726		Ziprasidone	C21H21ClN4OS	60854	Minor		Inter Info	[408], [409]
	UGT induction					Drug Num: 1
Drug ID		Drug Name	Formula	Pubchem ID	Severity Level		Interaction Detail	REF
D1377		Raltegravir	C20H21FN6O5	54671008	Minor		Inter Info	[4], [53], [54], [406]
	Competitive inhibition of metabolic enzyme					Drug Num: 2
Drug ID		Drug Name	Formula	Pubchem ID	Severity Level		Interaction Detail	REF
D0696		Fosnetupitant	C31H35F6N4O5P	71544786	Moderate		Inter Info	[53], [210], [211]
D1127		Netupitant	C30H32F6N4O	6451149	Moderate		Inter Info	[53], [210], [211]
Pharmacodynamic additive effects
	Increased risk of hepatotoxicity					Drug Num: 18
Drug ID		Drug Name	Formula	Pubchem ID	Severity Level		Interaction Detail	REF
D0900		Leflunomide	C12H9F3N2O2	3899	Major		Inter Info	[4], [5], [6]
D0944		Lomitapide	C39H37F6N3O2	9853053	Major		Inter Info	[7]
D1073		Mipomersen	C230H324N67O122P19S19	118984467	Major		Inter Info	[9]
D1258		Pexidartinib	C20H15ClF3N5	25151352	Major		Inter Info	[10]
D1556		Teriflunomide	C12H9F3N2O2	54684141	Major		Inter Info	[4], [5], [6]
D0826		Interferon beta-1a	NA	NA	Moderate		Inter Info	[22], [23], [24], [25]
D0827		Interferon beta-1b	NA	NA	Moderate		Inter Info	[22], [23], [24], [25]
D0149		Bedaquiline	C32H31BrN2O2	5388906	Moderate		Inter Info	[78]
D0199		Brentuximab vedotin	NA	NA	Moderate		Inter Info	[84]
D0248		Cannabidiol	C21H30O2	644019	Moderate		Inter Info	[54], [107]
D0357		Clofarabine	C10H11ClFN5O3	119182	Moderate		Inter Info	[117]
D0789		Idelalisib	C22H18FN7O	11625818	Moderate		Inter Info	[225]
D1025		Methotrexate	C20H22N8O5	126941	Moderate		Inter Info	[54], [268]
D1106		Naltrexone	C20H23NO4	5360515	Moderate		Inter Info	[279]
D1239		Peginterferon beta-1a	NA	NA	Moderate		Inter Info	[22], [23], [24], [25]
D1389		Remdesivir	C27H35N6O8P	121304016	Moderate		Inter Info	[53], [54], [315], [316], [317]
D1589		Tioguanine	C5H5N5S	2723601	Moderate		Inter Info	[363], [364]
D1615		Trabectedin	C39H43N3O11S	108150	Moderate		Inter Info	[54], [369]
	Increased risk of hypoglycemia					Drug Num: 22
Drug ID		Drug Name	Formula	Pubchem ID	Severity Level		Interaction Detail	REF
D1862		Pegvisomant	NA	NA	Moderate		Inter Info	[29], [30], [31]
D1270		Phentermine	C10H15N	4771	Moderate		Inter Info	[32], [33], [34]
D0165		Benzphetamine	C17H21N	5311017	Moderate		Inter Info	[32], [33], [34]
D1759		Chromic chloride	NA	NA	Moderate		Inter Info	[111], [112], [113]
D0341		Ciprofloxacin	C17H18FN3O3	2764	Moderate		Inter Info	[114], [115], [116]
D0438		Delafloxacin	C18H12ClF3N4O4	487101	Moderate		Inter Info	[114], [115], [116]
D0486		Diethylpropion	C13H19NO	7029	Moderate		Inter Info	[32], [33], [34]
D0641		Fenfluramine	C12H16F3N	3337	Moderate		Inter Info	[32], [33], [34]
D0716		Gemifloxacin	C18H20FN5O4	9571107	Moderate		Inter Info	[114], [115], [116]
D0723		Ginseng	C42H66O17	420552	Moderate		Inter Info	[216], [217], [218]
D0919		Levofloxacin	C18H20FN3O4	149096	Moderate		Inter Info	[114], [115], [116]
D0952		Lorcaserin	C11H14ClN	11658860	Moderate		Inter Info	[32], [33], [34]
D1012		Metamfetamine	C10H15N	10836	Moderate		Inter Info	[32], [33], [34]
D1092		Moxifloxacin	C21H24FN3O4	152946	Moderate		Inter Info	[114], [115], [116]
D1155		Norfloxacin	C16H18FN3O3	4539	Moderate		Inter Info	[114], [115], [116]
D1187		Orlistat	C29H53NO5	3034010	Moderate		Inter Info	[32], [33], [34]
D1262		Phendimetrazine	C12H17NO	30487	Moderate		Inter Info	[32], [33], [34]
D1464		Sibutramine	C17H26ClN	5210	Moderate		Inter Info	[32], [33], [34]
D1657		Trovafloxacin	C20H15F3N4O3	62959	Moderate		Inter Info	[114], [115], [116]
D1661		Turmeric	C21H20O6	969516	Moderate		Inter Info	[371], [372], [373]
D1836		Lipoic acid	C8H14O2S2	6112	Minor		Inter Info	[30], [389], [390]
D0711		Garlic	NA	NA	Minor		Inter Info	[398], [399], [400]
Pharmacodynamic antagonistic effects
	Antagonize the effect of antidiabetic agents					Drug Num: 106
Drug ID		Drug Name	Formula	Pubchem ID	Severity Level		Interaction Detail	REF
D0712		Gatifloxacin	C19H22FN3O4	5379	Major		Inter Info	[1], [2], [3]
D0114		Asparaginase Escherichia coli	NA	NA	Moderate		Inter Info	[12], [13], [14]
D0737		Goserelin	C59H84N18O14	5311128	Moderate		Inter Info	[12], [13], [14]
D0908		Leuprolide	C59H84N16O12	657181	Moderate		Inter Info	[12], [13], [14]
D1163		Octreotide	C49H66N10O10S2	448601	Moderate		Inter Info	[26], [27], [28]
D1234		Pegaspargase	C14H19NO	436058	Moderate		Inter Info	[12], [13], [14]
D1494		Somatotropin	NA	NA	Moderate		Inter Info	[12], [13], [14]
D0012		Acetazolamide	C4H6N4O3S2	1986	Moderate		Inter Info	[12], [13], [14]
D0112		Asenapine	C17H16ClNO	3036780	Moderate		Inter Info	[12], [13], [14]
D0113		Asparaginase Erwinia chrysanthemi	NA	NA	Moderate		Inter Info	[12], [13], [14]
D0172		Betamethasone	C22H29FO5	9782	Moderate		Inter Info	[12], [13], [14]
D0217		Bumetanide	C17H20N2O5S	2471	Moderate		Inter Info	[12], [13], [14]
D0232		Calaspargase pegol	NA	NA	Moderate		Inter Info	[12], [13], [14]
D0302		Ceritinib	C28H36ClN5O3S	57379345	Moderate		Inter Info	[12], [13], [14]
D0321		Chlorothiazide	C7H6ClN3O4S2	2720	Moderate		Inter Info	[12], [13], [14]
D0326		Chlorthalidone	C14H11ClN2O4S	2732	Moderate		Inter Info	[12], [13], [14]
D0370		Clozapine	C18H19ClN4	135398737	Moderate		Inter Info	[12], [13], [14]
D0388		Conjugated estrogens (topical)	C18H21NaO5S	45357473	Moderate		Inter Info	[12], [13], [14]
D0389		Copanlisib	C23H28N8O4	135565596	Moderate		Inter Info	[12], [13], [14]
D0392		Corticotropin	C207H308N56O58S	16132265	Moderate		Inter Info	[12], [13], [14]
D0416		Danazol	C22H27NO2	28417	Moderate		Inter Info	[12], [13], [14]
D0436		Deflazacort	C25H31NO6	189821	Moderate		Inter Info	[12], [13], [14]
D0474		Diazoxide	C8H7ClN2O2S	3019	Moderate		Inter Info	[12], [13], [14]
D0479		Diclofenamide	C6H6Cl2N2O4S2	3038	Moderate		Inter Info	[12], [13], [14]
D0510		Dobutamine	C18H23NO3	36811	Moderate		Inter Info	[12], [13], [14]
D0517		Dopamine	C8H11NO2	681	Moderate		Inter Info	[12], [13], [14]
D0571		Enfortumab vedotin	NA	NA	Moderate		Inter Info	[12], [13], [14]
D0579		Ephedrine	C10H15NO	9294	Moderate		Inter Info	[12], [13], [14]
D0581		Epinephrine	C9H13NO3	5816	Moderate		Inter Info	[12], [13], [14]
D0608		Estramustine	C23H31Cl2NO3	259331	Moderate		Inter Info	[12], [13], [14]
D0611		Estrone sulfate (topical)	C18H22O5S	3001028	Moderate		Inter Info	[12], [13], [14]
D0613		Etacrynic acid	C13H12Cl2O4	3278	Moderate		Inter Info	[12], [13], [14]
D0671		Fludrocortisone	C21H29FO5	31378	Moderate		Inter Info	[12], [13], [14]
D0678		Fluphenazine	C22H26F3N3OS	3372	Moderate		Inter Info	[12], [13], [14]
D0691		Formoterol	C19H24N2O4	3410	Moderate		Inter Info	[12], [13], [14]
D0697		Fosphenytoin	C16H15N2O6P	56339	Moderate		Inter Info	[12], [13], [14]
D0704		Furosemide	C12H11ClN2O5S	3440	Moderate		Inter Info	[12], [13], [14]
D0758		Histrelin	C66H86N18O12	25077993	Moderate		Inter Info	[12], [13], [14]
D0771		Hydrochlorothiazide	C7H8ClN3O4S2	3639	Moderate		Inter Info	[12], [13], [14]
D0775		Hydroflumethiazide	C8H8F3N3O4S2	3647	Moderate		Inter Info	[12], [13], [14]
D0797		Indacaterol	C24H28N2O3	6918554	Moderate		Inter Info	[12], [13], [14]
D0798		Indapamide	C16H16ClN3O3S	3702	Moderate		Inter Info	[12], [13], [14]
D0858		Isoniazid	C6H7N3O	3767	Moderate		Inter Info	[12], [13], [14]
D0859		Isoprenaline	C11H17NO3	3779	Moderate		Inter Info	[12], [13], [14]
D0891		Lanreotide	C54H69N11O10S2	71349	Moderate		Inter Info	[26], [27], [28]
D0925		Levothyroxine	C15H11I4NO4	5819	Moderate		Inter Info	[12], [13], [14]
D0934		Liothyronine	C15H12I3NO4	5920	Moderate		Inter Info	[12], [13], [14]
D0935		Liotrix	C30H21I7N2Na2O8	71371	Moderate		Inter Info	[12], [13], [14]
D0961		Lurasidone	C28H36N4O2S	213046	Moderate		Inter Info	[12], [13], [14]
D1010		Mesoridazine	C21H26N2OS2	4078	Moderate		Inter Info	[12], [13], [14]
D1018		Methazolamide	C5H8N4O3S2	4100	Moderate		Inter Info	[12], [13], [14]
D1041		Methylprednisolone	C22H30O5	6741	Moderate		Inter Info	[12], [13], [14]
D1048		Metolazone	C16H16ClN3O3S	4170	Moderate		Inter Info	[12], [13], [14]
D1129		Niacin	C6H5NO2	938	Moderate		Inter Info	[12], [13], [14]
D1153		Norepinephrine	C8H11NO3	439260	Moderate		Inter Info	[12], [13], [14]
D1166		Olanzapine	C17H20N4S	135398745	Moderate		Inter Info	[12], [13], [14]
D1171		Olodaterol	C21H26N2O5	11504295	Moderate		Inter Info	[12], [13], [14]
D1174		Omacetaxine mepesuccinate	C29H39NO9	285033	Moderate		Inter Info	[12], [13], [14]
D1185		Orciprenaline	C11H17NO3	4086	Moderate		Inter Info	[12], [13], [14]
D1215		Paliperidone	C23H27FN4O3	115237	Moderate		Inter Info	[12], [13], [14]
D1246		Pentamidine	C19H24N4O2	4735	Moderate		Inter Info	[295], [296], [297]
D1257		Perphenazine	C21H26ClN3OS	4748	Moderate		Inter Info	[12], [13], [14]
D1281		Phenylpropanolamine	C9H13NO	26934	Moderate		Inter Info	[12], [13], [14]
D1283		Phenytoin	C15H12N2O2	1775	Moderate		Inter Info	[12], [13], [14]
D1311		Polythiazide	C11H13ClF3N3O4S3	4870	Moderate		Inter Info	[12], [13], [14]
D1332		Prednisolone	C21H28O5	5755	Moderate		Inter Info	[12], [13], [14]
D1334		Prednisone	C21H26O5	5865	Moderate		Inter Info	[12], [13], [14]
D1346		Prochlorperazine	C20H24ClN3S	4917	Moderate		Inter Info	[12], [13], [14]
D1352		Promethazine	C17H20N2S	4927	Moderate		Inter Info	[12], [13], [14]
D1363		Pseudoephedrine	C10H15NO	7028	Moderate		Inter Info	[12], [13], [14]
D1413		Risperidone	C23H27FN4O2	5073	Moderate		Inter Info	[12], [13], [14]
D1438		Salbutamol	C13H21NO3	2083	Moderate		Inter Info	[12], [13], [14]
D1440		Salmeterol	C25H37NO4	5152	Moderate		Inter Info	[12], [13], [14]
D1493		Somapacitan	C54H95N13O20S2	129894493	Moderate		Inter Info	[12], [13], [14]
D1531		Tagraxofusp	NA	NA	Moderate		Inter Info	[12], [13], [14]
D1900		Teprotumumab	NA	NA	Moderate		Inter Info	[12], [13], [14]
D1554		Terbutaline	C12H19NO3	5403	Moderate		Inter Info	[12], [13], [14]
D1902		Tesamorelin	C221H366N72O67S	16137828	Moderate		Inter Info	[12], [13], [14]
D1563		Tetracosactide	C136H210N40O31S	16133802	Moderate		Inter Info	[12], [13], [14]
D1574		Thioridazine	C21H26N2S2	5452	Moderate		Inter Info	[12], [13], [14]
D1577		Thyroid, porcine	NA	NA	Moderate		Inter Info	[12], [13], [14]
D1611		Torasemide	C16H20N4O3S	41781	Moderate		Inter Info	[12], [13], [14]
D1628		Triamcinolone	C21H27FO6	31307	Moderate		Inter Info	[12], [13], [14]
D1630		Triamcinolone (ophthalmic)	C21H27FO6	31307	Moderate		Inter Info	[12], [13], [14]
D1637		Trifluoperazine	C21H24F3N3S	5566	Moderate		Inter Info	[12], [13], [14]
D1651		Triptorelin	C64H82N18O13	25074470	Moderate		Inter Info	[12], [13], [14]
D1695		Vilanterol	C24H33Cl2NO5	10184665	Moderate		Inter Info	[12], [13], [14]
D1707		Vorinostat	C14H20N2O3	5311	Moderate		Inter Info	[12], [13], [14]
D1735		Alclometasone (topical)	C22H29ClO5	5311000	Minor		Inter Info	[391], [392], [393]
D1737		Amcinonide	C28H35FO7	443958	Minor		Inter Info	[391], [392], [393]
D1748		Betamethasone (topical)	C22H29FO5	9782	Minor		Inter Info	[391], [392], [393]
D1762		Clobetasol (topical)	C22H28ClFO4	5311051	Minor		Inter Info	[391], [392], [393]
D1763		Clocortolone (topical)	C22H28ClFO4	5311052	Minor		Inter Info	[391], [392], [393]
D1770		Desonide (topical)	C24H32O6	5311066	Minor		Inter Info	[391], [392], [393]
D1771		Desoximetasone (topical)	C22H29FO4	5311067	Minor		Inter Info	[391], [392], [393]
D0455		Dexamethasone (ophthalmic)	C22H29FO5	5743	Minor		Inter Info	[54], [29], [30]
D1773		Diflorasone (topical)	C22H28F2O5	71415	Minor		Inter Info	[391], [392], [393]
D1786		Fluocinonide (topical)	C26H32F2O7	9642	Minor		Inter Info	[391], [392], [393]
D1788		Flurandrenolide (topical)	C24H33FO6	15209	Minor		Inter Info	[391], [392], [393]
D0685		Fluticasone (topical)	C22H27F3O4S	5311101	Minor		Inter Info	[391], [392], [393]
D1804		Halcinonide (topical)	C24H32ClFO5	443943	Minor		Inter Info	[391], [392], [393]
D1813		Hydrocortisone (topical)	C21H30O5	5754	Minor		Inter Info	[391], [392], [393]
D1844		Methylprednisolone (topical)	C22H30O5	6741	Minor		Inter Info	[391], [392], [393]
D1869		Prednicarbate (topical)	C27H36O8	6714002	Minor		Inter Info	[391], [392], [393]
D1911		Triamcinolone (topical)	C21H27FO6	31307	Minor		Inter Info	[391], [392], [393]
D1916		Ulobetasol (topical)	C22H27ClF2O4	5311167	Minor		Inter Info	[391], [392], [393]
	Antagonize the effect of antihypertensive agents					Drug Num: 1
Drug ID		Drug Name	Formula	Pubchem ID	Severity Level		Interaction Detail	REF
D1908		Thyrotropin alfa	C16H22N6O4	32281	Moderate		Inter Info	[12], [13], [14]

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294	Product Information. Pemazyre (pemigatinib). Incyte Corporation, Wilmington, DE.
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406	Product Information. Isentress (raltegravir). Merck & Company Inc, West Point, PA.
407	Product Information. Sonata (zaleplon) Wyeth-Ayerst Laboratories, Philadelphia, PA.
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