Details of Drug

Details of Drug

 Drug General Information (ID: D1648)
  Drug Name
Trioxsalen
  Drug Type Small molecule
  Drug Synonymous
trioxsalen; 3902-71-4; Trioxysalen; Trisoralen; Trimethylpsoralen; 4,5',8-Trimethylpsoralen; Elder 8011; Trioxysalenum; Trioxisaleno; Trioxysalene; 2',4,8-Trimethylpsoralen; 4,5',8-Trimethylpsoralene; NSC-71047; 2,5,9-Trimethyl-7H-furo[3,2-g]chromen-7-one; UNII-Y6UY8OV51T; Trioxysalene [INN-French]; Trioxysalenum [INN-Latin]; NSC71047; Trioxisaleno [INN-Spanish]; NSC 71047; TRIOXSALIN; 7H-Furo[3,2-g][1]benzopyran-7-one, 2,5,9-trimethyl-; EINECS 223-459-0; 4,8,5'-Trimethylpsoralen; BRN 0221723; Y6UY8OV51T
    Click to Show/Hide
  Disease Class ED63: Acquired hypomelanotic disorder
  Therapeutic Class Pigmenting Photosensitizing Agents
  Structure Could Not Find 2D Structure
3D Structure 2D Structure
  Formula C14H12O3
  InChI 1S/C14H12O3/c1-7-4-12(15)17-14-9(3)13-10(6-11(7)14)5-8(2)16-13/h4-6H,1-3H3
  InChIKey FMHHVULEAZTJMA-UHFFFAOYSA-N
  Canonical SMILES CC1=CC(=O)OC2=C1C=C3C=C(OC3=C2C)C
  External Link
Pubchem ID 5585
CAS Number 3902-71-4
CHEBI ID 28329
TTD ID D0FA2O

Drug-Drug Interaction Network
  Sunburst Graph
AM006  Pharmacodynamic additive effects
BM075  Increased risk of photosensitivity reactions
  Relation Graph
 Full list of drugs interacting with Trioxsalen
      Pharmacodynamic additive effects
   Increased risk of photosensitivity reactions Drug Num:  5
Drug ID
 
Drug Name
 Formula Pubchem ID Severity Level Interaction Detail REF
D0063
 
Aminolevulinic acid (topical)
 
C5H9NO3
 
137 
Moderate    Inter Info   
[1], [2], [3]
D1028
 
Methoxsalen
 
C12H8O4
 
4114 
Moderate    Inter Info   
[1], [4], [5], [6], [7]
D1033
 
Methyl aminolevulinate (topical)
 
C6H11NO3
 
157922 
Moderate    Inter Info   
[1], [2], [3]
D1314
 
Porfimer sodium
 
C68H74N8O11
 
135577896 
Moderate    Inter Info   
[8], [2], [9]
D1691
 
Verteporfin
 
C82H84N8O16
 
11980904 
Moderate    Inter Info   
[2], [4], [5], [10]
References
1 Cerner Multum, Inc. "Australian Product Information.".
2 Cerner Multum, Inc. "UK Summary of Product Characteristics.".
3 Product Information. Metvixia (methyl aminolevulinate topical). Galderma Laboratories Inc, Cranbury, NJ.
4 Multum Information Services, Inc. Expert Review Panel.
5 Product Information. Nulibry (fosdenopterin). Origin Biosciences Inc, Boston, MA.
6 Product Information. Oxsoralen (methoxsalen). ICN Pharmaceuticals Inc, Costa Mesa, CA.
7 Product Information. Uvadex (methoxsalen). Therakos Inc, Exton, PA.
8 Blakely KM, Drucker AM, Rosen CF "Drug-induced photosensitivity-an update: Culprit drugs, prevention and management." Drug Saf 42 (2019): 827-47. [PMID: 30888626]
9 Product Information. Photofrin (porfimer). Sanofi Winthrop Pharmaceuticals, New York, NY.
10 Product Information. Visudyne (verteporfin) Valeant Pharmaceuticals, Costa Mesa, CA.