Details of Drug

Details of Drug

 Drug General Information (ID: D1565)
  Drug Name
Tetracycline (topical)
  Drug Type Small molecule
  Drug Synonymous
Amycin; Biocycline; Bristaciclin; Bristaciclina; Bristacycline; Ciclibion; Copharlan; Cyclomycin; Cytome; Dumocyclin; Enterocycline; Medocycline; Resteclin; Robitet; Sanclomycine; Tetrachel; Veracin; Bristaciclin alpha; Cefracycline suspension; Component of Tetrastatin; Sumycin syrup; Tetracycline Free Base; Tetracycline I; Tetracycline II; Tetracycline Monohydrochloride; Achromycin (naphthacene derivative); Achromycin, naphthacene derivative; Centet (base); Lemtrex (base); Liquamycin (Veterinary); Liquamycin, veterinary; Panmycin (TN); Piracaps (base); Polycycline (VAN); Polycycline (antibiotic); Polycycline, antibiotic; SK-Tetracycline; Sumycin (TN); T-125; Tetra-Co; Tetraciclina [INN-Spanish]; Tetracycline & VRC3375; Tetracycline (internal use); Tetracyclinum [INN-Latin]; Tetracyn (TN); Vetquamycin-324 (free base); Tetracycline (JAN/USP/INN); Tetracycline [USAN:INN:BAN:JAN]; Methyl-1,11-dioxo-2-naphthacenecarboxamide; 6-Methyl-1,11-dioxy-2-naphthacenecarboxamide
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  Disease Class 1A00-1C4Z: Bacterial infection
  Therapeutic Class Antibiotics
  Structure Could Not Find 2D Structure
3D Structure 2D Structure
  Formula C22H24N2O8
  InChI 1S/C22H24N2O8/c1-21(31)8-5-4-6-11(25)12(8)16(26)13-9(21)7-10-15(24(2)3)17(27)14(20(23)30)19(29)22(10,32)18(13)28/h4-6,9-10,15,25-26,29,31-32H,7H2,1-3H3,(H2,23,30)/t9-,10-,15-,21+,22-/m0/s1
  InChIKey NWXMGUDVXFXRIG-WESIUVDSSA-N
  Canonical SMILES CC1(C2CC3C(C(=O)C(=C(C3(C(=O)C2=C(C4=C1C=CC=C4O)O)O)O)C(=O)N)N(C)C)O
  External Link
Pubchem ID 54675776
CAS Number 60-54-8
CHEBI ID 27902
TTD ID D08NQZ
INTEDE ID DR1568
VARIDT ID DR00127

Drug-Drug Interaction Network
  Sunburst Graph
AM006  Pharmacodynamic additive effects
BM075  Increased risk of photosensitivity reactions
  Relation Graph
 Full list of drugs interacting with Tetracycline (topical)
      Pharmacodynamic additive effects
   Increased risk of photosensitivity reactions Drug Num:  5
Drug ID
 
Drug Name
 Formula Pubchem ID Severity Level Interaction Detail REF
D1028
 
Methoxsalen
 
C12H8O4
 
4114 
Moderate    Inter Info   
[1], [2], [3]
D1314
 
Porfimer sodium
 
C68H74N8O11
 
135577896 
Moderate    Inter Info   
[4], [5], [6]
D0063
 
Aminolevulinic acid (topical)
 
C5H9NO3
 
137 
Moderate    Inter Info   
[1], [5], [7]
D1033
 
Methyl aminolevulinate (topical)
 
C6H11NO3
 
157922 
Moderate    Inter Info   
[1], [5], [7]
D1691
 
Verteporfin
 
C82H84N8O16
 
11980904 
Moderate    Inter Info   
[5], [2], [8]
References
1 Cerner Multum, Inc. "Australian Product Information.".
2 Multum Information Services, Inc. Expert Review Panel.
3 Product Information. Uvadex (methoxsalen). Therakos Inc, Exton, PA.
4 Blakely KM, Drucker AM, Rosen CF "Drug-induced photosensitivity-an update: Culprit drugs, prevention and management." Drug Saf 42 (2019): 827-47. [PMID: 30888626]
5 Cerner Multum, Inc. "UK Summary of Product Characteristics.".
6 Product Information. Photofrin (porfimer). Sanofi Winthrop Pharmaceuticals, New York, NY.
7 Product Information. Metvixia (methyl aminolevulinate topical). Galderma Laboratories Inc, Cranbury, NJ.
8 Product Information. Visudyne (verteporfin) Valeant Pharmaceuticals, Costa Mesa, CA.