Details of Drug

Details of Drug

 Drug General Information (ID: D1500)
  Drug Name
Spectinomycin
  Drug Type Small molecule
  Drug Synonymous
Actinospectacin; Actinospectacina; Adspec; Espectinomicina; Prospec; SCM; SPCM; Spectam; Spectinomicina; Spectinomycine; Spectinomycinum; Spectogard; Stanilo; Togamycin; Trobicin; Actinospectacina [Italian]; Spectam Scour Halt; Spectinomicina [Italian]; Spectinomycin Di HCl; Spectinomycin HCl; Spectinomycin dihydrochloride; Spectinomycin hydrochloride; Spectinomycin hydrochloride anhydrous; Spectinomycin monohydrochloride; Spectinomycin sulfate; Antibiotic 2233wp; M 141; U 18409; U 18409 E; Actinospectacin, hydrochloride; Adspec (TN); Espectinomicina [INN-Spanish]; M-141; Prospec (TN); Spectinomycin (INN); Spectinomycin Dihydrochloride, Anhydrous; Spectinomycin Dihydrochloride, Pentahydrate; SpectinomycinHCl/ Sulphate; Spectinomycin Hydrochloride (anhydrous); Spectinomycin [INN:BAN]; Spectinomycine [INN-French]; Spectinomycinum [INN-Latin]; Trobicin (TN); U-18409AE; XK 43-1; Togamycin sulfate (1:1); ACTINOSPECTACIN, ESPECTINOMICINA, CHX-3101; (2R,4aR,5aR,6S,7S,8R,9S,9aR,10aS)-4a,7,9-trihydroxy-2-methyl-6,8-bis(methylamino)decahydro-4H-pyrano[2,3-b][1,4]benzodioxin-4-one; (2R-(2alpha,4abeta,5abeta,6beta,7beta,8beta,9alpha,9aalpha,10abeta))-Decahydro-4a,7,9-trihydroxy-2-methyl-6,8-bis(methylamino)-4H-pyrano(2,3-b)(1,4)benzodioxin-4-one monohydrochloride; 4H-Pyrano[2,3-b][1,4]benzodioxin-4-one, decahydro-4a,7,9-trihydroxy-2-methyl-6,8-bis(methylamino)-, [2R-(2.alpha.,4a.beta.,5a.beta.,6.beta.,7.beta.,8.beta.,9.alpha.,9a.alpha.,10a.beta.)]-, sulfate (1:1) (salt)
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  Disease Class 1A00-1C4Z: Bacterial infection
  Therapeutic Class Antibiotics
  Structure Could Not Find 2D Structure
3D Structure 2D Structure
  Formula C14H24N2O7
  InChI 1S/C14H24N2O7/c1-5-4-6(17)14(20)13(21-5)22-12-10(19)7(15-2)9(18)8(16-3)11(12)23-14/h5,7-13,15-16,18-20H,4H2,1-3H3/t5-,7-,8+,9+,10+,11-,12-,13+,14+/m1/s1
  InChIKey UNFWWIHTNXNPBV-WXKVUWSESA-N
  Canonical SMILES CC1CC(=O)C2(C(O1)OC3C(C(C(C(C3O2)NC)O)NC)O)O
  External Link
Pubchem ID 15541
CAS Number 1695-77-8
CHEBI ID 9215
TTD ID D02PCR
INTEDE ID DR2379

Drug-Drug Interaction Network
  Sunburst Graph
AM003  Affected organization distribution
AM006  Pharmacodynamic additive effects
AM007  Pharmacodynamic antagonistic effects
BM014  Interference of cell/tissue uptake
BM045  Additive neuromuscular blocking effects
BM100  Antagonize the effect of vaccine/toxoid
BM107  Attenuated pharmacological effects (Unspecific)
  Relation Graph
 Full list of drugs interacting with Spectinomycin
      Affected organization distribution
   Interference of cell/tissue uptake Drug Num:  1
Drug ID
 
Drug Name
 Formula Pubchem ID Severity Level Interaction Detail REF
D1817
 
Indium In-111 oxyquinoline
 
C27H18InN3O3
 
16685037 
Moderate    Inter Info   
[10]
      Pharmacodynamic additive effects
   Additive neuromuscular blocking effects Drug Num:  9
Drug ID
 
Drug Name
 Formula Pubchem ID Severity Level Interaction Detail REF
D0196
 
Botulinum toxin type A
 
NA
 
NA
Major    Inter Info   
[1], [2], [3]
D0197
 
Botulinum Toxin Type B
 
NA
 
NA
Major    Inter Info   
[1], [2], [3]
D0343
 
Cisatracurium
 
C53H72N2O12+2
 
62887 
Moderate    Inter Info   
[8], [9]
D1420
 
Rocuronium
 
C32H53N2O4+
 
441290 
Moderate    Inter Info   
[8], [9]
D0122
 
Atracurium
 
C53H72N2O12+2
 
47319 
Moderate    Inter Info   
[8], [9]
D1080
 
Mivacurium
 
C58H80N2O14+2
 
5281042 
Moderate    Inter Info   
[8], [9]
D1219
 
Pancuronium
 
C35H60N2O4+2
 
441289 
Moderate    Inter Info   
[8], [9]
D1684
 
Vecuronium
 
C34H57N2O4+
 
39765 
Moderate    Inter Info   
[8], [9]
D1510
 
Succinylcholine
 
C14H30N2O4+2
 
5314 
Moderate    Inter Info   
[8], [9]
      Pharmacodynamic antagonistic effects
   Antagonize the effect of vaccine/toxoid Drug Num:  2
Drug ID
 
Drug Name
 Formula Pubchem ID Severity Level Interaction Detail REF
D1914
 
Typhoid vaccine (live)
 
NA
 
NA
Major    Inter Info   
[4], [5], [6]
D1693
 
Vibrio cholerae CVD 103-HgR strain live antigen (live)
 
NA
 
NA
Major    Inter Info   
[7]
   Attenuated pharmacological effects (Unspecific) Drug Num:  1
Drug ID
 
Drug Name
 Formula Pubchem ID Severity Level Interaction Detail REF
D1287
 
Picosulfuric acid
 
C18H15NO8S2
 
5243 
Moderate    Inter Info   
[11], [12], [13]
References
1 Product Information. Myobloc (botulinum toxin type B) Elan Pharmaceuticals, S. San Francisco, CA.
2 Product Information. Dysport (abobotulinumtoxinA). Tercica Inc, Brisbane, CA.
3 Product Information. Jeuveau (prabotulinumtoxinA). Evolus, Inc., Santa Barbara, CA.
4 Cerner Multum, Inc. "UK Summary of Product Characteristics.".
5 UK government "Typhoid.".
6 American Medical Association, Division of Drugs and Toxicology "Drug evaluations annual 1994." Chicago, IL: American Medical Association (1994).
7 Product Information. Vaxchora (cholera vaccine, live). PaxVax, Miami, FL.
8 Multum Information Services, Inc. Expert Review Panel.
9 Product Information. Anectine (succinylcholine). Glaxo Wellcome, Research Triangle Park, NC.
10 Product Information. Indium Oxyquinoline In-111 (indium oxyquinoline In-111). GE Healthcare, Princeton, NJ.
11 Product Information. Prepopik (citric acid/Mg oxide/Na picosulfate). Ferring Pharmaceuticals Inc, Tarrytown, NY.
12 MHRA. Medicines and Healthcare Regulatory Agency (general site Reference).
13 Product Information. Clenpiq (citric acid/Mg oxide/Na picosulfate). Ferring Pharmaceuticals Inc, Tarrytown, NY.