Details of Drug

Details of Drug

 Drug General Information (ID: D1489)
  Drug Name
Sodium zirconium cyclosilicate
  Drug Type Small molecule
  Drug Synonymous
UZSi 9; ZS-9 compound; Sodium zirconium silicate (Na2ZrSi3O9); UZSi-9; CBTCHTJSGLCFMY-UHFFFAOYSA-N; 543686-27-7
    Click to Show/Hide
  Disease Class 5C76: Hyperkalaemia
  Therapeutic Class Cation Exchange Resins
  Structure Could Not Find 2D Structure
3D Structure 2D Structure
  Formula H6Na2O9Si3Zr+2
  InChI 1S/2Na.H6O9Si3.Zr/c;;1-10(2)7-11(3,4)9-12(5,6)8-10;/h;;1-6H;/q2*+1;;
  InChIKey CBTCHTJSGLCFMY-UHFFFAOYSA-N
  Canonical SMILES O[Si]1(O[Si](O[Si](O1)(O)O)(O)O)O.[Na+].[Na+].[Zr]
  External Link
Pubchem ID 91799284
CAS Number 17141-74-1
TTD ID D03AZK

Drug-Drug Interaction Network
  Sunburst Graph
AM001  Affected gastrointestinal absorption
BM005  Altered gastric pH
  Relation Graph
 Full list of drugs interacting with Sodium zirconium cyclosilicate
      Affected gastrointestinal absorption
   Altered gastric pH Drug Num:  16
Drug ID
 
Drug Name
 Formula Pubchem ID Severity Level Interaction Detail REF
D0116
 
Atazanavir
 
C38H52N6O7
 
148192 
Moderate    Inter Info   
[1], [2]
D0120
 
Atorvastatin
 
C33H35FN2O5
 
60823 
Moderate    Inter Info   
[1], [2]
D0428
 
Dasatinib
 
C22H26ClN7O2S
 
3062316 
Moderate    Inter Info   
[1], [2]
D0595
 
Erlotinib
 
C22H23N3O4
 
176870 
Moderate    Inter Info   
[1], [2]
D0704
 
Furosemide
 
C12H11ClN2O5S
 
3440 
Moderate    Inter Info   
[1], [2]
D0799
 
Indinavir
 
C36H47N5O4
 
5362440 
Moderate    Inter Info   
[1], [2]
D0867
 
Itraconazole
 
C35H38Cl2N8O4
 
55283 
Moderate    Inter Info   
[1], [2]
D0880
 
Ketoconazole
 
C26H28Cl2N4O4
 
456201 
Moderate    Inter Info   
[1], [2]
D0898
 
Ledipasvir
 
C49H54F2N8O6
 
67505836 
Moderate    Inter Info   
[1], [2]
D1119
 
Nelfinavir
 
C32H45N3O4S
 
64143 
Moderate    Inter Info   
[1], [2]
D1136
 
Nilotinib
 
C28H22F3N7O
 
644241 
Moderate    Inter Info   
[1], [2]
D1315
 
Posaconazole
 
C37H42F2N8O4
 
468595 
Moderate    Inter Info   
[1], [2]
D1377
 
Raltegravir
 
C20H21FN6O5
 
54671008 
Moderate    Inter Info   
[1], [2]
D1404
 
Rilpivirine
 
C22H18N6
 
6451164 
Moderate    Inter Info   
[1], [2]
D1415
 
Ritonavir
 
C37H48N6O5S2
 
392622 
Moderate    Inter Info   
[1], [2]
D1444
 
Saquinavir
 
C38H50N6O5
 
441243 
Moderate    Inter Info   
[1], [2]
References
1 Cerner Multum, Inc. "UK Summary of Product Characteristics.".
2 Product Information. Lokelma (sodium zirconium cyclosilicate). Astra-Zeneca Pharmaceuticals, Wilmington, DE.