Details of Drug

Drug General Information (ID: D1374)
Drug Name	Racepinephrine
Drug Type	Small molecule
Drug Synonymous	DL-Adrenaline; 329-65-7; dl-Epinephrine; Racepinefrine; Racepinephrine; Epinephrine racemic; (+-)-Adrenaline; Racepinefrina; Racepinefrinum; Epirenamine; (+-)-Epinephrine; DL-Adrenalin; 4-(1-hydroxy-2-(methylamino)ethyl)benzene-1,2-diol; Vaponefrin; D-Epinephrine; 4-[1-hydroxy-2-(methylamino)ethyl]benzene-1,2-diol; 2-(Methylamino)-1-(3,4-dihydroxyphenyl)ethanol; L-(-)-EPINEPHRINE; Alipogene tiparvovec; d-Adrenaline; (+/-)-adrenaline; 1,2-Benzenediol, 4-[1-hydroxy-2-(methylamino)ethyl]-; 1-(3,4-Dihydroxy)phenyl-2-methylaminoethanol; CHEMBL1740; Micronefrin; Suprarenin; CHEBI:33568; ( )-Epinephrine; L-(+)-Adrenaline; 6912-68-1; (+/-)-Epinephrine;DL-Adrenaline;(+/-)-Adrenaline; Micronephrine; Epinephrine dl-; MLS001333244; (-)-Epinephrine (+)-bitartrate salt;L-Adrenaline (+)-bitartrate salt; D-(+)-Epinephrine; (+/-)-Epinephrine; BRN 2938799; Racepinefrine, (S)-; Racepinefrinum [INN-Latin]; Racemic Epinephrine; Racepinefrina [INN-Spanish]; 929881-05-0; Racepinephrine [USP]; SMR000058236; EINECS 206-347-6; 1,2-Benzenediol, 4-(1-hydroxy-2-(methylamino)ethyl)-; BRN 2212160; Epinepherine; rac Epinephrine; CCRIS 8140; Epinephrine-d3; Epinephrine-d6; DL-Adrenali; Racemic adrenaline; Adrenaline,(S); Epinephrine, dl-; Adrenaline, racemic; Epinephrine dl form; Epinephrine dl-form; (plusmn)-adrenaline; Epinephrine, Racemic; Racepinefrine [INN]; (+-)-3,4-Dihydroxy-alpha-((methylamino)methyl)benzyl alcohol; (R,S)-3,4-Dihydroxy-alpha-((methylamino)methyl)benzylalkohol; EPINEPHRINE,(+); (.+/-.)-Adrenaline; Racemic mixture adrenaline; (.+/-.)-Epinephrine; Oxidized-adrenal-ferredoxin; Racemic mixture epinephrine; 4-[1-Hydroxy-2-(methylamino)ethyl]-1,2-benzenediol #; Adrenaline, racemic mixture; Mixture adrenaline, racemic; Racepinephrine (USP/INN); AROCLOR1016; cid_5924; SCHEMBL3815; Epinephrine, racemic mixture; Mixture epinephrine, racemic; (r)-4-(1-hydroxy-2-(methylamino)ethyl)benzene-1,2-diol; Hydrochloride, racepinephrine; NCIOpen2_000082; Lopac0_000522; GTPL509; 4-13-00-02927 (Beilstein Handbook Reference); SGCUT00008; BDBM84342; DTXSID80858965; (+/-)-Epinephrine, >=95%; HMS3259B19; HMS3656E12; 1,2-Benzenediol, 4-(1-hydroxy-2-(methylamino)ethyl)-, (+-)-; 104655-05-2; BCP17220; HY-B0447; to_000046; AC-395; BBL028091; Benzyl alcohol, 3,4-dihydroxy-alpha-((methylamino)methyl)-, (+-)-; PDSP1_000587; PDSP2_000584; s2523; STL146338; AKOS005721043; CCG-204612; MCULE-4868062157; NC00671; SDCCGSBI-0050505.P002; BRN-2938799; ( inverted exclamation markA)-Adrenaline; Adrenaline hydrochloride, racemic mixture; NCGC00015417-02; NCGC00015417-03; NCGC00015417-16; NCGC00162177-01; ( inverted exclamation markA)-Epinephrine; AS-12580; Epinephrine hydrochloride, racemic mixture; A0172; FT-0625455; FT-0695432; D05688; D88221; AB00514461_07; 329A657; A821533; L000877; 4-(1-hydroxy-2-methylaminoethyl)benzene-1,2-diol; J-018952; Q7279006; SR-01000075862-8; 4-(1-Hydroxy-2-methylamino-ethyl)-benzene-1,2-diol; 4-[1-hydroxy-2-(methylamino)ethyl]benzene-1,2-diol, 1; 9561B8BB-366F-4A33-B295-1C6E682AC6BB; (.+/-.)-4-[1-Hydroxy-2-(methylamino)ethyl]-1,2-benzenediol; 4-[1-hydroxy-2-(methylamino)ethyl]pyrocatechol;hydrochloride; (.+/-.)-3,4-Dihydroxy-.alpha.-[(methylamino)methyl]benzyl alcohol; 1,2-Benzenediol, 4-[1-hydroxy-2-(methylamino)ethyl]-, (.+/-.)-; 4-[1-hydroxy-2-(methylamino)ethyl]benzene-1,2-diol;DL-Adrenaline; 4-[2-(methylamino)-1-oxidanyl-ethyl]benzene-1,2-diol;hydrochloride; Benzyl alcohol, 3,4-dihydroxy-.alpha.-((methylamino)methyl)-, (.+/-.)-; ( inverted exclamation markA)-Epinephrine;( inverted exclamation markA)-Adrenaline;DL-Adrenaline; (+/-)-Epinephrine-D6 solution, 100 mug/mL in methanol with 5% 1 M HCl, ampule of 1 mL, certified reference material Click to Show/Hide
Therapeutic Class	Adrenergic Bronchodilators
Structure
Structure	3D Structure		2D Structure
Formula	C9H13NO3
InChI	InChI=1S/C9H13NO3/c1-10-5-9(13)6-2-3-7(11)8(12)4-6/h2-4,9-13H,5H2,1H3
InChIKey	UCTWMZQNUQWSLP-UHFFFAOYSA-N
Canonical SMILES	CNCC(C1=CC(=C(C=C1)O)O)O
External Link
External Link	Pubchem ID	838

Drug-Drug Interaction Network
Sunburst Graph		Legend Information AM001 Affected gastrointestinal absorption AM006 Pharmacodynamic additive effects AM007 Pharmacodynamic antagonistic effects BM009 Altered absorption (Unspecific) BM041 Additive hypertensive effects BM065 Increased risk of hypokalemia BM078 Increased risk of rapid heart rate BM081 Increased risk of ventricular arrhythmias BM083 Potentiated the pharmacological effects (Unspecific) BM090 Antagonize the effect of bronchodilators
Relation Graph

Full list of drugs interacting with Racepinephrine
Affected gastrointestinal absorption
	Altered absorption (Unspecific)					Drug Num: 1
Drug ID		Drug Name	Formula	Pubchem ID	Severity Level		Interaction Detail	REF
D0814		Insulin human (inhalation, rapid acting)	C257H383N65O77S6	118984375	Moderate		Inter Info	[26], [27], [28]
Pharmacodynamic additive effects
	Additive hypertensive effects					Drug Num: 81
Drug ID		Drug Name	Formula	Pubchem ID	Severity Level		Interaction Detail	REF
D0377		Cocaine (nasal)	C17H21NO4	446220	Major		Inter Info	[4], [5], [6]
D0378		Cocaine (topical)	C17H21NO4	446220	Major		Inter Info	[4], [5], [6]
D0068		Amitriptyline	C20H23N	2160	Moderate		Inter Info	[7], [8], [9]
D0072		Amoxapine	C17H16ClN3O	2170	Moderate		Inter Info	[7], [8], [9]
D0074		Amphetamine	C9H13N	3007	Moderate		Inter Info	[10], [11], [12]
D0103		Arformoterol	C19H24N2O4	3083544	Moderate		Inter Info	[13], [14], [15]
D0106		Armodafinil	C15H15NO2S	9690109	Moderate		Inter Info	[13], [14], [15]
D0119		Atomoxetine	C17H21NO	54841	Moderate		Inter Info	[10], [11], [12]
D0165		Benzphetamine	C17H21N	5311017	Moderate		Inter Info	[10], [11], [12]
D0361		Clomipramine	C19H23ClN2	2801	Moderate		Inter Info	[7], [8], [9]
D0446		Desipramine	C18H22N2	2995	Moderate		Inter Info	[7], [8], [9]
D0451		Desvenlafaxine	C16H25NO2	125017	Moderate		Inter Info	[16], [17], [18], [19], [20], [21]
D0460		Dexmethylphenidate	C14H19NO2	154101	Moderate		Inter Info	[10], [11], [12]
D0465		Dextroamphetamine	C9H13N	5826	Moderate		Inter Info	[10], [11], [12]
D0486		Diethylpropion	C13H19NO	7029	Moderate		Inter Info	[10], [11], [12]
D0505		Dipivefrin (ophthalmic)	C19H29NO5	3105	Moderate		Inter Info	[13], [14], [15]
D0510		Dobutamine	C18H23NO3	36811	Moderate		Inter Info	[13], [14], [15]
D0517		Dopamine	C8H11NO2	681	Moderate		Inter Info	[13], [14], [15]
D0523		Doxapram	C24H30N2O2	3156	Moderate		Inter Info	[10], [11], [12]
D0525		Doxepin	C19H21NO	667477	Moderate		Inter Info	[7], [8], [9]
D0526		Doxepin (topical)	C19H21NO	667477	Moderate		Inter Info	[7], [8], [9]
D0538		Droxidopa	C9H11NO5	92974	Moderate		Inter Info	[25]
D0539		Duloxetine	C18H19NOS	60835	Moderate		Inter Info	[16], [17], [18], [19], [20], [21]
D0579		Ephedrine	C10H15NO	9294	Moderate		Inter Info	[13], [14], [15]
D0581		Epinephrine	C9H13NO3	5816	Moderate		Inter Info	[13], [14], [15]
D0583		Epinephrine (topical)	C9H13NO3	5816	Moderate		Inter Info	[13], [14], [15]
D0641		Fenfluramine	C12H16F3N	3337	Moderate		Inter Info	[13], [14], [15]
D0691		Formoterol	C19H24N2O4	3410	Moderate		Inter Info	[13], [14], [15]
D0778		Hydroxyamphetamine (ophthalmic)	C9H13NO	3651	Moderate		Inter Info	[13], [14], [15]
D0795		Imipramine	C19H24N2	3696	Moderate		Inter Info	[7], [8], [9]
D0797		Indacaterol	C24H28N2O3	6918554	Moderate		Inter Info	[13], [14], [15]
D0853		Isocarboxazid	C12H13N3O2	3759	Moderate		Inter Info	[29], [30], [31], [32], [33], [7], [14], [34], [15], [8], [35], [9], [36], [37], [38], [39], [40], [41]
D0857		Isometheptene	C9H19N	22297	Moderate		Inter Info	[13], [14], [15]
D0859		Isoprenaline	C11H17NO3	3779	Moderate		Inter Info	[13], [14], [15]
D0920		Levomilnacipran	C15H22N2O	6917779	Moderate		Inter Info	[16], [17], [18], [19], [20], [21]
D0921		Levonordefrin	C9H13NO3	164739	Moderate		Inter Info	[13], [14], [15]
D0933		Linezolid	C16H20FN3O4	441401	Moderate		Inter Info	[29], [30], [31], [32], [33], [7], [14], [34], [15], [8], [35], [9], [36], [37], [38], [39], [40], [41]
D0937		Lisdexamfetamine	C15H25N3O	11597698	Moderate		Inter Info	[10], [11], [12]
D1012		Metamfetamine	C10H15N	10836	Moderate		Inter Info	[10], [11], [12]
D1036		Methylene blue	C16H18ClN3S	6099	Moderate		Inter Info	[29], [30], [31], [32], [33], [7], [14], [34], [15], [8], [35], [9], [36], [37], [38], [39], [40], [41]
D1039		Methylphenidate	C14H19NO2	4158	Moderate		Inter Info	[10], [11], [12]
D1061		Midodrine	C12H18N2O4	4195	Moderate		Inter Info	[13], [14], [15]
D1066		Milnacipran	C15H22N2O	65833	Moderate		Inter Info	[16], [17], [18], [19], [20], [21]
D1081		Modafinil	C15H15NO2S	4236	Moderate		Inter Info	[13], [14], [15]
D1108		Naphazoline (ophthalmic)	C14H14N2	4436	Moderate		Inter Info	[13], [14], [15]
D1153		Norepinephrine	C8H11NO3	439260	Moderate		Inter Info	[13], [14], [15]
D1158		Nortriptyline	C19H21N	4543	Moderate		Inter Info	[7], [8], [9]
D1171		Olodaterol	C21H26N2O5	11504295	Moderate		Inter Info	[13], [14], [15]
D1185		Orciprenaline	C11H17NO3	4086	Moderate		Inter Info	[13], [14], [15]
D1204		Oxymetazoline (nasal)	C16H24N2O	4636	Moderate		Inter Info	[13], [14], [15]
D1205		Oxymetazoline (ophthalmic)	C16H24N2O	4636	Moderate		Inter Info	[13], [14], [15]
D1206		Oxymetazoline (topical)	C16H24N2O	4636	Moderate		Inter Info	[13], [14], [15]
D1262		Phendimetrazine	C12H17NO	30487	Moderate		Inter Info	[10], [11], [12]
D1270		Phentermine	C10H15N	4771	Moderate		Inter Info	[10], [11], [12]
D1276		Phenylephrine	C9H13NO2	6041	Moderate		Inter Info	[13], [14], [15]
D1277		Phenylephrine (nasal)	C9H13NO2	6041	Moderate		Inter Info	[13], [14], [15]
D1278		Phenylephrine (ophthalmic)	C9H13NO2	6041	Moderate		Inter Info	[13], [14], [15]
D1280		Phenylephrine (topical)	C9H13NO2	6041	Moderate		Inter Info	[13], [14], [15]
D1281		Phenylpropanolamine	C9H13NO	26934	Moderate		Inter Info	[10], [11], [12]
D1298		Pirbuterol	C12H20N2O3	4845	Moderate		Inter Info	[13], [14], [15]
D1345		Procarbazine	C12H19N3O	4915	Moderate		Inter Info	[29], [30], [31], [32], [33], [7], [14], [34], [15], [8], [35], [9], [36], [37], [38], [39], [40], [41]
D1358		Propylhexedrine (nasal)	C10H21N	7558	Moderate		Inter Info	[13], [14], [15]
D1361		Protriptyline	C19H21N	4976	Moderate		Inter Info	[7], [8], [9]
D1363		Pseudoephedrine	C10H15NO	7028	Moderate		Inter Info	[13], [14], [15]
D0924		Levosalbutamol	C13H21NO3	123600	Moderate		Inter Info	[13], [14], [15]
D1211		Ozanimod	C23H24N4O3	52938427	Moderate		Inter Info	[29], [30], [31], [32], [33], [7], [14], [34], [15], [8], [35], [9], [36], [37], [38], [39], [40], [41]
D1492		Solriamfetol	C10H14N2O2	10130337	Moderate		Inter Info	[45]
D1385		Rasagiline	C12H13N	3052776	Moderate		Inter Info	[29], [30], [31], [32], [33], [7], [14], [34], [15], [8], [35], [9], [36], [37], [38], [39], [40], [41]
D1437		Safinamide	C17H19FN2O2	131682	Moderate		Inter Info	[29], [30], [31], [32], [33], [7], [14], [34], [15], [8], [35], [9], [36], [37], [38], [39], [40], [41]
D1438		Salbutamol	C13H21NO3	2083	Moderate		Inter Info	[13], [14], [15]
D1440		Salmeterol	C25H37NO4	5152	Moderate		Inter Info	[13], [14], [15]
D1455		Selegiline	C13H17N	26757	Moderate		Inter Info	[29], [30], [31], [32], [33], [7], [14], [34], [15], [8], [35], [9], [36], [37], [38], [39], [40], [41]
D1464		Sibutramine	C17H26ClN	5210	Moderate		Inter Info	[46]
D1535		Tapentadol	C14H23NO	9838022	Moderate		Inter Info	[16], [17], [18], [19], [20], [21]
D1554		Terbutaline	C12H19NO3	5403	Moderate		Inter Info	[13], [14], [15]
D1567		Tetryzoline (nasal)	C13H16N2	5419	Moderate		Inter Info	[13], [14], [15]
D1568		Tetryzoline (ophthalmic)	C13H16N2	5419	Moderate		Inter Info	[13], [14], [15]
D1620		Tranylcypromine	C9H11N	19493	Moderate		Inter Info	[29], [30], [31], [32], [33], [7], [14], [34], [15], [8], [35], [9], [36], [37], [38], [39], [40], [41]
D1647		Trimipramine	C20H26N2	5584	Moderate		Inter Info	[7], [8], [9]
D1689		Venlafaxine	C17H27NO2	5656	Moderate		Inter Info	[16], [17], [18], [19], [20], [21]
D1695		Vilanterol	C24H33Cl2NO5	10184665	Moderate		Inter Info	[13], [14], [15]
	Increased risk of hypokalemia					Drug Num: 15
Drug ID		Drug Name	Formula	Pubchem ID	Severity Level		Interaction Detail	REF
D0148		Beclomethasone dipropionate	C28H37ClO7	21700	Minor		Inter Info	[47], [4], [8]
D0172		Betamethasone	C22H29FO5	9782	Minor		Inter Info	[48], [47], [4], [8]
D0215		Budesonide	C25H34O6	5281004	Minor		Inter Info	[48], [47], [4], [8]
D0333		Ciclesonide	C32H44O7	6918155	Minor		Inter Info	[48], [47], [4], [8]
D0392		Corticotropin	C207H308N56O58S	16132265	Minor		Inter Info	[48], [47], [4], [8]
D0453		Dexamethasone	C22H29FO5	5743	Minor		Inter Info	[48], [47], [4], [8]
D0671		Fludrocortisone	C21H29FO5	31378	Minor		Inter Info	[48], [47], [4], [8]
D0672		Flunisolide	C24H31FO6	82153	Minor		Inter Info	[48], [47], [4], [8]
D0773		Hydrocortisone	C21H30O5	5754	Minor		Inter Info	[48], [47], [4], [8]
D1041		Methylprednisolone	C22H30O5	6741	Minor		Inter Info	[48], [47], [4], [8]
D1332		Prednisolone	C21H28O5	5755	Minor		Inter Info	[48], [47], [4], [8]
D1334		Prednisone	C21H26O5	5865	Minor		Inter Info	[48], [47], [4], [8]
D0683		Fluticasone	C22H27F3O4S	5311101	Minor		Inter Info	[48], [47], [4], [8]
D1563		Tetracosactide	C136H210N40O31S	16133802	Minor		Inter Info	[47], [4], [8]
D1628		Triamcinolone	C21H27FO6	31307	Minor		Inter Info	[48], [47], [4], [8]
	Increased risk of ventricular arrhythmias					Drug Num: 1
Drug ID		Drug Name	Formula	Pubchem ID	Severity Level		Interaction Detail	REF
D0491		Digoxin	C41H64O14	2724385	Moderate		Inter Info	[22], [23], [24]
	Potentiated the pharmacological effects (Unspecific)					Drug Num: 3
Drug ID		Drug Name	Formula	Pubchem ID	Severity Level		Interaction Detail	REF
D0925		Levothyroxine	C15H11I4NO4	5819	Moderate		Inter Info	[42], [43], [44]
D0934		Liothyronine	C15H12I3NO4	5920	Moderate		Inter Info	[42], [43], [44]
D1577		Thyroid, porcine	NA	NA	Moderate		Inter Info	[42], [43], [44]
Pharmacodynamic antagonistic effects
	Antagonize the effect of bronchodilators					Drug Num: 11
Drug ID		Drug Name	Formula	Pubchem ID	Severity Level		Interaction Detail	REF
D0266		Carteolol (ophthalmic)	C16H24N2O3	2583	Major		Inter Info	[1], [2], [3]
D0267		Carvedilol	C24H26N2O4	2585	Major		Inter Info	[1], [2], [3]
D0884		Labetalol	C19H24N2O3	3869	Major		Inter Info	[1], [2], [3]
D0915		Levobunolol (ophthalmic)	C17H25NO3	39468	Major		Inter Info	[1], [2], [3]
D1045		Metipranolol (ophthalmic)	C17H27NO4	31477	Major		Inter Info	[1], [2], [3]
D1098		Nadolol	C17H27NO4	39147	Major		Inter Info	[1], [2], [3]
D1293		Pindolol	C14H20N2O2	4828	Major		Inter Info	[1], [2], [3]
D1357		Propranolol	C16H21NO2	4946	Major		Inter Info	[1], [2], [3]
D1498		Sotalol	C12H20N2O3S	5253	Major		Inter Info	[1], [2], [3]
D1585		Timolol	C13H24N4O3S	33624	Major		Inter Info	[1], [2], [3]
D1586		Timolol (ophthalmic)	C13H24N4O3S	33624	Major		Inter Info	[1], [2], [3]

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33	Product Information. Alupent (metaproterenol). Boehringer-Ingelheim, Ridgefield, CT.
34	Product Information. Brethaire (terbutaline). Novartis Pharmaceuticals, East Hanover, NJ.
35	Product Information. Isuprel (isoproterenol). Sanofi Winthrop Pharmaceuticals, New York, NY.
36	Product Information. Proventil (albuterol). Schering Laboratories, Kenilworth, NJ.
37	Product Information. S2 Inhalant (racepinephrine). Nephron Pharmaceuticals, Orlando, FL.
38	Product Information. Severent (salmeterol). Glaxo Wellcome, Research Triangle Park, NC.
39	Product Information. Striverdi Respimat (olodaterol). Boehringer Ingelheim, Ridgefield, CT.
40	Product Information. Tornalate Metered Dose (bitolterol). Dura Pharmaceuticals, San Diego, CA.
41	Product Information. Xopenex (levalbuterol). Sepracor, Marlborough, MA.
42	Product Information. Armour thyroid (thyroid desiccated). Forest Pharmaceuticals, St. Louis, MO.
43	Product Information. Synthroid (levothyroxine). Abbott Pharmaceutical, Abbott Park, IL.
44	Agencia Espaola de Medicamentos y Productos Sanitarios Healthcare "Centro de informacion online de medicamentos de la AEMPS - CIMA."
45	Product Information. Sunosi (solriamfetol). Jazz Pharmaceuticals, Palo Alto, CA.
46	Product Information. Meridia (sibutramine). Knoll Pharmaceutical Company, Whippany, NJ.
47	Cerner Multum, Inc. "Australian Product Information.".
48	Agencia Espaola de Medicamentos y Productos Sanitarios Healthcare "Centro de informacion online de medicamentos de la AEMPS - CIMA.".

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